2014
EGFR activation suppresses respiratory virus-induced IRF1-dependent CXCL10 production
Kalinowski A, Ueki I, Min-Oo G, Ballon-Landa E, Knoff D, Galen B, Lanier LL, Nadel JA, Koff JL. EGFR activation suppresses respiratory virus-induced IRF1-dependent CXCL10 production. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2014, 307: l186-l196. PMID: 24838750, PMCID: PMC4101792, DOI: 10.1152/ajplung.00368.2013.Peer-Reviewed Original ResearchConceptsRespiratory viral infectionsRespiratory syncytial virusCXCL10 productionRespiratory virusesViral infectionIFN regulatory factorAirway epitheliumEGFR activationChronic obstructive pulmonary diseaseEpithelial cellsExacerbation of asthmaObstructive pulmonary diseaseRecruitment of lymphocytesAdaptive immune responsesAirway epithelial cellsNADPH oxidase activationInhibition of EGFRVirus-infected cellsHuman viral pathogensPulmonary diseaseSyncytial virusEpithelial productionIL-8Viral pneumoniaEpidermal growth factor receptor (EGFR) activation
2006
Case Report: A Case of Wood-Smoke–Related Pulmonary Disease
Diaz J, Koff J, Gotway M, Nishimura S, Balmes J. Case Report: A Case of Wood-Smoke–Related Pulmonary Disease. Environmental Health Perspectives 2006, 114: 759-762. PMID: 16675433, PMCID: PMC1459932, DOI: 10.1289/ehp.8489.Peer-Reviewed Original ResearchConceptsPulmonary diseaseThickened bronchovascular bundlesThoracic computed tomographyChronic productive coughChronic obstructive pulmonary diseaseObstructive pulmonary diseaseHealth care providersBiomass smokeExposure to biomass smokeLung biopsyProductive coughBronchovascular bundlesPulmonary nodulesLung cancerPulmonary clinicClinical progressionCarbon-laden macrophagesRespiratory manifestationsBlack plaqueHistopathological abnormalitiesFibrotic scarLung parenchymaMild symptomsAmount of smokingCare providers