2009
Association Between COMT, PTSD, and Increased Smoking Following Hurricane Exposure in an Epidemiologic Sample
Amstadter AB, Nugent NR, Koenen KC, Ruggiero KJ, Acierno R, Galea S, Kilpatrick DG, Gelernter J. Association Between COMT, PTSD, and Increased Smoking Following Hurricane Exposure in an Epidemiologic Sample. Psychiatry 2009, 72: 360-369. PMID: 20070134, PMCID: PMC2808117, DOI: 10.1521/psyc.2009.72.4.360.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderCigarette smokingCOMT Val158MetFrequency of smokingSaliva DNA samplesFirst genetic association studyFlorida Hurricane StudyAge of initiationCOMT Val158Met polymorphismTobacco smokingSmokingEpidemiologic samplePossible associationAcute stressorStress disorderVal158Met polymorphismHurricane exposureTraumatic eventsGenetic association studiesVal158MetAssociationEuropean American malesDNA samplesAssociation studiesInitiationVariation in RGS2 is Associated with Suicidal Ideation in an Epidemiological Study of Adults Exposed to the 2004 Florida Hurricanes
Amstadter AB, Koenen KC, Ruggiero KJ, Acierno R, Galea S, Kilpatrick DG, Gelernter J. Variation in RGS2 is Associated with Suicidal Ideation in an Epidemiological Study of Adults Exposed to the 2004 Florida Hurricanes. Archives Of Suicide Research 2009, 13: 349-357. PMID: 19813112, PMCID: PMC2760049, DOI: 10.1080/13811110903266541.Peer-Reviewed Original ResearchConceptsSuicidal ideationCurrent suicidal ideationEpidemiologic sampleRandom digit dial proceduresSingle nucleotide polymorphismsEpidemiological studiesBuccal DNA samplesFlorida hurricanesCurrent ideationIdeationAdultsHurricane exposureRs4606RGS2Social supportNucleotide polymorphismsRiskDNA samplesParticipantsSymptoms
1993
Mutational analysis of candidate genes in psychiatric disorders
Gejman P, Gelernter J. Mutational analysis of candidate genes in psychiatric disorders. American Journal Of Medical Genetics 1993, 48: 184-191. PMID: 8135301, DOI: 10.1002/ajmg.1320480404.Peer-Reviewed Original ResearchConceptsMutational analysisDNA samplesGradient gel electrophoresis (DGGE) techniqueDNA sequencesNucleotide sequenceSequence variationCandidate genesSequence variantsNew sequence variationsChemical cleavageGel electrophoresis techniqueExistence of variationGenetic hypothesisGenesMolecular screeningMutation screeningAffected individualsSequenceElectrophoresis techniqueMutationsCleavageVariationVariants