2024
Puzzling undetectable haptoglobin in a transfused pregnant patient
Chaves Rivera M, Choucair I, Vera M, El-Khoury J, Figueroa Villalba C. Puzzling undetectable haptoglobin in a transfused pregnant patient. Clinica Chimica Acta 2024, 561: 119829. PMID: 38917868, DOI: 10.1016/j.cca.2024.119829.Peer-Reviewed Original ResearchAcute hemolytic transfusion reactionUndetectable haptoglobin levelUndetectable haptoglobinPregnant patientsHaptoglobin levelsB-cell acute lymphocytic leukemiaPregnancy-related physiological changesTrimester-specific reference intervalsReference intervalsCenters for Disease Control (CDC) criteriaDiagnosis of hemolysisNon-pregnant counterpartsTrimester of pregnancyAcute lymphocytic leukemiaHemolytic transfusion reactionsMultidisciplinary approach to patient careFollow-up visitRed cell unitsLactate dehydrogenasePhysiological changesRBC transfusionThird trimesterLymphocytic leukemiaLaboratory findingsImmunological markers
2022
Low haptoglobin in pregnancy: physiological or intravascular hemolysis?
Villalba C, Choucair I, Vera M, Lee E, El-Khoury J. Low haptoglobin in pregnancy: physiological or intravascular hemolysis? American Journal Of Clinical Pathology 2022, 158: s6-s6. DOI: 10.1093/ajcp/aqac126.009.Peer-Reviewed Original ResearchAcute hemolytic transfusion reactionTrimester-specific reference intervalsNormal lactate dehydrogenaseSecond trimesterThird trimesterFirst trimesterReference intervalsIntravascular hemolysisLactate dehydrogenaseLow haptoglobinB-cell acute lymphoblastic leukemiaRemnant serum samplesDisease Control criteriaElevated total bilirubinRed cell transfusionNon-pregnant populationHemolytic transfusion reactionsHigh estrogen statesAcute lymphoblastic leukemiaLow haptoglobin levelsCombination of pregnancyQuality improvement projectOverall reference intervalRed cell unitsInduction chemotherapy
2020
First- and Second-Trimester Reference Intervals for Thyroid Function Testing in a US Population
Bunch DR, Firmender K, Harb R, El-Khoury JM. First- and Second-Trimester Reference Intervals for Thyroid Function Testing in a US Population. American Journal Of Clinical Pathology 2020, 155: 776-780. PMID: 33210132, DOI: 10.1093/ajcp/aqaa165.Peer-Reviewed Original ResearchConceptsThyroid-stimulating hormoneTrimester-specific reference intervalsThyroid function testsMIU/LPmol/LReference intervalsFunction testsUS populationSecond trimester prenatal screeningRoche analyzersThyroid function testingNegative screening resultsSpecific reference intervalsRoche Modular E170Singleton pregnanciesThyroglobulin antibodiesThyroid dysfunctionFirst trimesterSecond trimesterAdverse outcomesFunction testingFree thyroxineTotal triiodothyronineTotal thyroxineModular E170