2024
Biomarkers vs Machines: The Race to Predict Acute Kidney Injury
Ghazi L, Farhat K, Hoenig M, Durant T, El-Khoury J. Biomarkers vs Machines: The Race to Predict Acute Kidney Injury. Clinical Chemistry 2024, 70: 805-819. PMID: 38299927, DOI: 10.1093/clinchem/hvad217.Peer-Reviewed Original ResearchAcute kidney injuryEarly diagnosisInsulin-like growth factor-binding protein 7Prediction of acute kidney injuryGrowth factor-binding protein 7Detect acute kidney injuryNeutrophil gelatinase-associated lipocalinAcute kidney injury detectionClinical practiceIrreversible kidney damageClinical outcome studiesImminent AKISerum creatinineKidney injuryInjury markersPediatric populationCystatin CTissue inhibitorHospitalized patientsClinical useKidney damageRegulatory approvalProtein 7BiomarkersOutcome studies
2014
Recent advances in MS methods for nicotine and metabolite analysis in human matrices: clinical perspectives
El-Khoury JM, Wang S. Recent advances in MS methods for nicotine and metabolite analysis in human matrices: clinical perspectives. Bioanalysis 2014, 6: 2171-2183. PMID: 25331861, DOI: 10.4155/bio.14.176.Peer-Reviewed Original ResearchConceptsHuman matricesMajor global health issueSecond-hand exposureGlobal health issueTobacco smokingPreventable deathsTobacco consumptionAppropriate biomarkersHand exposureClinical MSNicotine metabolismClinical perspectiveTobacco productsHealth issuesNicotineMeasurement of nicotineMetabolitesStandard reference methodDetection of nicotineSmokingMetabolite analysisBiomarkersSuperior sensitivity