Melanoma × Macrophage Fusion Hybrids Acquire Increased Melanogenesis and Metastatic Potential: Altered N‐Glycosylation as an Underlying Mechanism
SODI S, CHAKRABORTY A, PLATT J, KOLESNIKOVA N, ROSEMBLAT S, KEH‐YEN A, BOLOGNIA J, RACHKOVSKY M, ORLOW S, PAWELEK J. Melanoma × Macrophage Fusion Hybrids Acquire Increased Melanogenesis and Metastatic Potential: Altered N‐Glycosylation as an Underlying Mechanism. Pigment Cell & Melanoma Research 1998, 11: 299-309. PMID: 9877101, DOI: 10.1111/j.1600-0749.1998.tb00739.x.Peer-Reviewed Original ResearchConceptsN-glycosylationLAMP-1Parental cellsN-glycosylation inhibitorMelanoma cellsCloudman S91 cellsMetastatic potentialImportant regulatory pathwayAltered N-glycosylationMajority of hybridsParental melanoma cellsCloudman S91 melanoma cellsRegulatory pathwaysMelanosomal proteinsCloudman melanoma cellsMelanotic phenotypeSame proteinS91 melanoma cellsIncreased glycosylationPigmentary systemCell lysatesS91 cellsUnderlying mechanismCloudman cellsGel electrophoresisWhat's new in the treatment of cutaneous melanoma?
Olhoffer I, Bolognia J. What's new in the treatment of cutaneous melanoma? Seminars In Cutaneous Medicine And Surgery 1998, 17: 96-107. PMID: 9669603, DOI: 10.1016/s1085-5629(98)80003-5.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAntineoplastic Combined Chemotherapy ProtocolsBiopsyCancer VaccinesChemotherapy, AdjuvantClinical Trials as TopicHumansImmunotherapyInterferonsInterleukinsLymph Node ExcisionLymph NodesLymphatic MetastasisMelanomaMohs SurgeryNeoplasm MetastasisNeoplasm StagingRadionuclide ImagingRemission InductionSkin NeoplasmsSurvival RateConceptsExcision of melanomaManagement of melanomaSentinel node biopsyRecent clinical trialsMohs micrographic surgeryForm of vaccinesAdjuvant immunotherapyAdvanced diseaseNode biopsySurgical marginsCutaneous melanomaAlpha interferonMicrographic surgeryClinical trialsLentigo malignaMelanomaBiochemotherapyImmunotherapyBiopsySurgeryMalignaVaccineExcisionDermatologistsDisease