1999
UV Light and MSH Receptors
CHAKRABORTY A, FUNASAKA Y, SLOMINSKI A, BOLOGNIA J, SODI S, ICHIHASHI M, PAWELEK J. UV Light and MSH Receptors. Annals Of The New York Academy Of Sciences 1999, 885: 100-116. PMID: 10816644, DOI: 10.1111/j.1749-6632.1999.tb08668.x.Peer-Reviewed Original ResearchConceptsMSH receptorsSun-exposed areasAlpha-MSH receptorsSkin of miceMSH receptor activityPOMC-derived peptidesAction of UVBEffects of UVBGuinea pigsReceptor activityUVB irradiationUltraviolet B radiationReceptor productionCellular responsivenessReceptorsUVB damageB radiationSkin pigmentationUVBHuman melanocytesCutaneous melanogenesisMSHMelanin contentResultant increaseSkin
1998
Melanoma × Macrophage Fusion Hybrids Acquire Increased Melanogenesis and Metastatic Potential: Altered N‐Glycosylation as an Underlying Mechanism
SODI S, CHAKRABORTY A, PLATT J, KOLESNIKOVA N, ROSEMBLAT S, KEH‐YEN A, BOLOGNIA J, RACHKOVSKY M, ORLOW S, PAWELEK J. Melanoma × Macrophage Fusion Hybrids Acquire Increased Melanogenesis and Metastatic Potential: Altered N‐Glycosylation as an Underlying Mechanism. Pigment Cell & Melanoma Research 1998, 11: 299-309. PMID: 9877101, DOI: 10.1111/j.1600-0749.1998.tb00739.x.Peer-Reviewed Original ResearchConceptsN-glycosylationLAMP-1Parental cellsN-glycosylation inhibitorMelanoma cellsCloudman S91 cellsMetastatic potentialImportant regulatory pathwayAltered N-glycosylationMajority of hybridsParental melanoma cellsCloudman S91 melanoma cellsRegulatory pathwaysMelanosomal proteinsCloudman melanoma cellsMelanotic phenotypeSame proteinS91 melanoma cellsIncreased glycosylationPigmentary systemCell lysatesS91 cellsUnderlying mechanismCloudman cellsGel electrophoresisMelanoma × macrophage hybrids with enhanced metastatic potential
Rachkovsky M, Sodi S, Chakraborty A, Avissar Y, Bolognia J, Madison McNiff J, Platt J, Bermudes D, Pawelek J. Melanoma × macrophage hybrids with enhanced metastatic potential. Clinical & Experimental Metastasis 1998, 16: 299-312. PMID: 9626809, DOI: 10.1023/a:1006557228604.Peer-Reviewed Original ResearchConceptsHigh metastatic potentialMetastatic potentialMelanoma cellsTumor-infiltrating leukocytesParental melanoma cellsLow metastatic potentialB16F10 melanoma cellsFibroblast-conditioned mediumCloudman S91 mouse melanoma cellsMetastatic melanoma cellsS91 mouse melanoma cellsVascular invasionMetastatic melanomaPrimary tumorNormal miceMelanoma metastasesEnhanced metastasisMetastasisDistant organsUseful new modelMouse melanoma cellsHigher chemotaxisMetastatic linesHuman macrophagesTumor cells
1995
Pentachrome vitiligo
Fargnoli M, Bolognia J. Pentachrome vitiligo. Journal Of The American Academy Of Dermatology 1995, 33: 853-856. PMID: 7593796, DOI: 10.1016/0190-9622(95)90422-0.Peer-Reviewed Case Reports and Technical NotesNeurotropic melanoma with prominent melanization
Barnhill R, Bolognia J. Neurotropic melanoma with prominent melanization. Journal Of Cutaneous Pathology 1995, 22: 450-459. PMID: 8594079, DOI: 10.1111/j.1600-0560.1995.tb00762.x.Peer-Reviewed Case Reports and Technical Notes
1994
The significance of eccentric foci of hyperpigmentation ('small dark dots') within melanocytic nevi. Analysis of 59 cases.
Bolognia J, Lin A, Shapiro P. The significance of eccentric foci of hyperpigmentation ('small dark dots') within melanocytic nevi. Analysis of 59 cases. JAMA Dermatology 1994, 130: 1013-7. PMID: 8053697, DOI: 10.1001/archderm.130.8.1013.Peer-Reviewed Original Research
1992
Molecular Cascades in UV Induced Melanogenesis: A Central Role for Melanotropins?
PAWELEK J, CHAKRABORTY A, OSBER M, ORLOW S, MIN K, ROSENZWEIG K, BOLOGNIA J. Molecular Cascades in UV Induced Melanogenesis: A Central Role for Melanotropins? Pigment Cell & Melanoma Research 1992, 5: 348-356. PMID: 1292019, DOI: 10.1111/j.1600-0749.1992.tb00561.x.Peer-Reviewed Original Research
1991
Structural/functional relationships between internal and external MSH receptors: Modulation of expression in Cloudman melanoma cells by UVB radiation
Chakraborty A, Orlow S, Bolognia J, Pawelek J. Structural/functional relationships between internal and external MSH receptors: Modulation of expression in Cloudman melanoma cells by UVB radiation. Journal Of Cellular Physiology 1991, 147: 1-6. PMID: 1903794, DOI: 10.1002/jcp.1041470102.Peer-Reviewed Original Research
1989
UVB-Induced Melanogenesis May Be Mediated Through the MSH-Receptor System
Bolognia J, Murray M, Pawelek J. UVB-Induced Melanogenesis May Be Mediated Through the MSH-Receptor System. Journal Of Investigative Dermatology 1989, 92: 651-656. PMID: 2497190, DOI: 10.1111/1523-1747.ep12696836.Peer-Reviewed Original ResearchConceptsMSH receptor activityUltraviolet B radiationReceptor activityMSH binding capacityMSH receptor systemMelanin-producing melanocytesUVB-induced melanogenesisHigh-affinity receptorGuinea pig skinEffects of UVBCloudman S91 mouse melanoma cellsS91 mouse melanoma cellsFamily of peptidesCutaneous melanocytesGuinea pigsMouse melanoma cellsAffinity receptorMelanoma cellsCellular responsivenessB radiationPig skinUVB lightCutaneous melanogenesisMelanocytesMSH
1988
A possible role for melanin precursors in regulating both pigmentation and proliferation of melanocytes.
Pawelek J, Bolognia J, McLane J, Murray M, Osber M, Słominski A. A possible role for melanin precursors in regulating both pigmentation and proliferation of melanocytes. Progress In Clinical And Biological Research 1988, 256: 143-54. PMID: 3130637.Peer-Reviewed Original Research