Featured Publications
Preoccupation in bulimia nervosa, binge‐eating disorder, anorexia nervosa, and higher weight
Lydecker JA, Simpson L, Smith SR, White MA, Grilo CM. Preoccupation in bulimia nervosa, binge‐eating disorder, anorexia nervosa, and higher weight. International Journal Of Eating Disorders 2021, 55: 76-84. PMID: 34713460, PMCID: PMC8963447, DOI: 10.1002/eat.23630.Peer-Reviewed Original ResearchConceptsEating-disorder psychopathologyBinge-eating disorderShape/weightStudy groupBulimia nervosaAnorexia nervosaFood/eatingDisorder treatment outcomesEating-disorder featuresCognitive behavioral therapyHigher body weightFood/Treatment outcomesBody weightHW groupWeb-based surveyFormal diagnosisOvert behavioral featuresNervosaDepressionDisordersSignificant differencesWeight preoccupationPsychopathologyEatingExamining sex as a predictor and moderator of treatment outcomes for binge‐eating disorder: Analysis of aggregated randomized controlled trials
Lydecker JA, Gueorguieva R, Masheb R, White MA, Grilo CM. Examining sex as a predictor and moderator of treatment outcomes for binge‐eating disorder: Analysis of aggregated randomized controlled trials. International Journal Of Eating Disorders 2019, 53: 20-30. PMID: 31497876, PMCID: PMC6983351, DOI: 10.1002/eat.23167.Peer-Reviewed Original ResearchMeSH KeywordsBinge-Eating DisorderFemaleHumansMaleMiddle AgedRandomized Controlled Trials as TopicSex FactorsTreatment OutcomeConceptsBinge-eating disorderEating-disorder psychopathologyCognitive behavioral therapySelf-report measuresModerators of outcomeTreatment outcomesBehavioral weight lossStatistical Manual-Fourth EditionSignificant moderatorWeight lossControl conditionModeratorCourse of treatmentBetter treatment outcomesGreater weight lossMain effectStructured interviewsTreatment settingsPsychopathologyMultimodal treatmentPatient groupRCT studiesMedical CenterBed treatmentParticipantsExamining Race as a Predictor and Moderator of Treatment Outcomes for Binge-Eating Disorder: Analysis of Aggregated Randomized Controlled Trials
Lydecker JA, Gueorguieva R, Masheb R, White MA, Grilo CM. Examining Race as a Predictor and Moderator of Treatment Outcomes for Binge-Eating Disorder: Analysis of Aggregated Randomized Controlled Trials. Journal Of Consulting And Clinical Psychology 2019, 87: 530-540. PMID: 31008634, PMCID: PMC6589831, DOI: 10.1037/ccp0000404.Peer-Reviewed Original ResearchConceptsBinge-eating disorderWhite participantsCognitive behavioral therapySelf-report measuresTreatment outcomesBinge-eating remissionModerate treatment outcomeBinge Eating DisorderBinge-eating episodesMain effectBlack participantsWeight lossBehavioral weight lossEvidence-based treatmentsLower depressionTreatment researchRandomized Controlled TrialsBetter treatment outcomesControl conditionParticipantsControlled TrialsMultimodal treatmentPercent weight lossPatient groupModeratorI didn't want them to see: Secretive eating among adults with binge‐eating disorder
Lydecker JA, Grilo CM. I didn't want them to see: Secretive eating among adults with binge‐eating disorder. International Journal Of Eating Disorders 2019, 52: 153-158. PMID: 30623972, PMCID: PMC6368878, DOI: 10.1002/eat.23002.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedBinge-Eating DisorderBody ImageBody WeightFemaleHumansMaleMiddle AgedYoung AdultConceptsBody mass indexBinge-eating disorderEating-disorder psychopathologyObjective binge-eating episodesSecretive eatingBinge-eating episodesGreater eating-disorder psychopathologyGreater body mass indexHigher depression scoresClinical characteristicsMass indexTreatment-seeking adultsDepression scoresPatientsShape/weightWeight concernsAdultsEatingSelf-report measuresDisordersShape concernsEpisodesGreater proportionPsychopathologyTreatment formulationDriven exercise in the absence of binge eating: Implications for purging disorder
Lydecker JA, Shea M, Grilo CM. Driven exercise in the absence of binge eating: Implications for purging disorder. International Journal Of Eating Disorders 2017, 51: 139-145. PMID: 29215743, PMCID: PMC5796839, DOI: 10.1002/eat.22811.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBinge-Eating DisorderExerciseFeeding BehaviorFemaleHumansSurveys and QuestionnairesYoung AdultConceptsEating-disorder psychopathologyClinical significancePhysical activityCompensatory behaviorsBinge-eating episodesAbsence of bingeEating Disorder PsychopathologyLower depression levelsLow-frequency thresholdsWeb-based surveyDepression levelsSmall sample sizeHigher depressionOverall frequencyLaxativesTreatment researchMost domainsExerciseBingePsychopathologyDisordersDepressionParticipantsSimilar levelsFurther supportForm and Formulation: Examining the Distinctiveness of Body Image Constructs in Treatment-Seeking Patients With Binge-Eating Disorder
Lydecker JA, White MA, Grilo CM. Form and Formulation: Examining the Distinctiveness of Body Image Constructs in Treatment-Seeking Patients With Binge-Eating Disorder. Journal Of Consulting And Clinical Psychology 2017, 85: 1095-1103. PMID: 29083224, PMCID: PMC5679782, DOI: 10.1037/ccp0000258.Peer-Reviewed Original ResearchMeSH KeywordsAdultBinge-Eating DisorderBody ImageBody Mass IndexBody WeightEmotionsFemaleHumansMaleMiddle AgedPersonal SatisfactionSelf ConceptConceptsBody image variablesBody image disturbanceBody image constructsBinge-eating disorderImage constructImage variablesWeight/shape overvaluationBinge-eating frequencyInvestigator-based interviewBiopsychosocial featuresEating-disorder psychopathologyTreatment-seeking patientsShape preoccupationShape dissatisfactionShape overvaluationShape concernsCore aspectsCurrent studyTreatment formulationConstructsImportant distinctionDifferent aspectsOvervaluationPreoccupationDisordersDoes your child's weight influence how you judge yourself as a parent? A cross-sectional study to define and examine parental overvaluation of weight/shape
Lydecker JA, Grilo CM. Does your child's weight influence how you judge yourself as a parent? A cross-sectional study to define and examine parental overvaluation of weight/shape. Preventive Medicine 2017, 105: 265-270. PMID: 28987340, PMCID: PMC5659758, DOI: 10.1016/j.ypmed.2017.10.009.Peer-Reviewed Original ResearchConceptsWeight/shapeParental overvaluationPersonal weightEating-disorder psychopathologyBinge-eating disorderEating PsychopathologyParent psychopathologyPediatric obesityDearth of researchChild weightCross-sectional designParental attitudesPsychopathologyImportant psychopathologyDisorder treatmentCross-sectional studyParentsCurrent studyIntegral stakeholdersWeight influenceOvervaluationClinical attentionChild BMIChild healthRelated conceptsChildren of parents with BED have more eating behavior disturbance than children of parents with obesity or healthy weight
Lydecker JA, Grilo CM. Children of parents with BED have more eating behavior disturbance than children of parents with obesity or healthy weight. International Journal Of Eating Disorders 2016, 50: 648-656. PMID: 27859458, PMCID: PMC5429220, DOI: 10.1002/eat.22648.Peer-Reviewed Original ResearchConceptsBinge-eating disorderChild weightChildren's bingeEating-disorder psychopathologyHigher child weightCross-sectional findingsChild overweightProspective confirmationChildren's eatingChild feedingChild overeatingDietary restrictionObesityClinical interventionsPrevention effortsEating Disorder BehaviorsDisordersBingePreliminary evidencePotential factorsEatingCurrent studyLimited literatureCore featuresOBCognitive‐behavioral therapy for binge‐eating disorder for non‐responders to initial acute treatments: Randomized controlled trial
Grilo C, Lydecker J, Gueorguieva R. Cognitive‐behavioral therapy for binge‐eating disorder for non‐responders to initial acute treatments: Randomized controlled trial. International Journal Of Eating Disorders 2023, 56: 1544-1553. PMID: 37144325, PMCID: PMC10524840, DOI: 10.1002/eat.23975.Peer-Reviewed Original ResearchMeSH KeywordsAdultBinge-Eating DisorderBulimiaCognitive Behavioral TherapyFemaleHumansMaleMiddle AgedObesityProspective StudiesTreatment OutcomeConceptsInitial acute treatmentBinge-eating disorderCognitive behavioral therapyAcute treatmentBinge-eating frequencyInitial interventionTherapist-led cognitive behavioural therapyInitial pharmacological treatmentTreat remission ratesEvidence-based treatmentsSingle-site trialAcute efficacyRemission rateAdult patientsInitial treatmentPharmacological treatmentPatientsPosttreatment assessmentBehavioral treatmentSufficient benefitTherapyDisordersInterventionTreatmentPharmacotherapy
2023
The Relationship of Self-identified Weight Status With Perceived Mental and Physical Health
Hamilton A, Smith S, Lydecker J. The Relationship of Self-identified Weight Status With Perceived Mental and Physical Health. Journal Of Psychiatric Practice 2023, 29: 430-438. PMID: 37948168, PMCID: PMC10653675, DOI: 10.1097/pra.0000000000000744.Peer-Reviewed Original ResearchMeSH KeywordsBinge-Eating DisorderFeeding and Eating DisordersHumansObesityOverweightPsychopathologyConceptsOW/OBBinge-eating disorderDisorder psychopathologyPhysical healthMental healthStudy groupBulimia nervosaOW/OB groupBN groupOverweight/obesityFuture clinical researchOB groupWeight statusObesityClinical researchBED groupOverweightDepressionHealthPsychopathologyDisordersGroupOBLow levelsAnalysis of varianceNaltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trial
Grilo C, Lydecker J, Jastreboff A, Pittman B, McKee S. Naltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trial. Obesity 2023, 31: 2762-2773. PMID: 37751990, PMCID: PMC10600891, DOI: 10.1002/oby.23898.Peer-Reviewed Original ResearchMeSH KeywordsBinge-Eating DisorderBulimiaBupropionDouble-Blind MethodFemaleHumansMaleMiddle AgedNaltrexoneObesityTreatment OutcomeWeight LossConceptsNaltrexone/bupropionBinge-eating disorderObesity statusLogistic regressionWeight lossPlacebo-controlled trialWeight loss outcomesPrevalent psychiatric disordersEvidence-based treatmentsPost-treatment assessmentBinge-eating frequencyGreater percentage weight lossMedication outcomesRemission ratePharmacological optionsPlaceboBupropionPsychiatric disordersPercentage weight lossMixed modelsDisordersObesityPatientsSignificant reductionWeight reductionNaltrexone plus bupropion combination medication maintenance treatment for binge-eating disorder following successful acute treatments: randomized double-blind placebo-controlled trial
Grilo C, Lydecker J, Gueorguieva R. Naltrexone plus bupropion combination medication maintenance treatment for binge-eating disorder following successful acute treatments: randomized double-blind placebo-controlled trial. Psychological Medicine 2023, 53: 7775-7784. PMID: 37366017, PMCID: PMC10751383, DOI: 10.1017/s0033291723001800.Peer-Reviewed Original ResearchMeSH KeywordsAdultBinge-Eating DisorderBulimiaBupropionDouble-Blind MethodFemaleHumansMaleMiddle AgedNaltrexoneObesityProspective StudiesTreatment OutcomeWeight LossConceptsNaltrexone/bupropionBinge-eating disorderBinge-eating remissionAcute treatmentMaintenance treatmentBinge-eating frequencyDouble-blind placebo-controlled trialBehavioral weight loss therapyWeight lossCo-occurring obesitySuccessful acute treatmentPlacebo-controlled trialWeight loss therapySignificant additional weight lossSingle-site trialAdditional weight lossAcute efficacyRemission rateAdult patientsComorbid obesityBupropionInitial interventionPosttreatment assessmentRespondersPlaceboLoss of control in binge‐eating disorder: Fear and resignation
Perelman H, Gilbert K, Grilo C, Lydecker J. Loss of control in binge‐eating disorder: Fear and resignation. International Journal Of Eating Disorders 2023, 56: 1199-1206. PMID: 36920120, PMCID: PMC10247475, DOI: 10.1002/eat.23929.Peer-Reviewed Original ResearchMeSH KeywordsAdultBariatric SurgeryBinge-Eating DisorderBulimia NervosaDepressionHumansHyperphagiaMaleConceptsBinge-eating disorderCognitive-affective experiencesLoss of controlModerate treatment outcomeBinge-eating episodesEating-disorder psychopathologyTreatment-seeking patientsFuture researchAbsence of fearGreater distressPsychopathologyFearSevere psychopathologyResearch cliniciansSemistructured interviewsTreatment formulationPast monthDisordersResignationTreatment outcomesExperienceBlack individualsEmotionsTreatment planningIndividuals
2022
Naltrexone-Bupropion and Behavior Therapy, Alone and Combined, for Binge-Eating Disorder: Randomized Double-Blind Placebo-Controlled Trial
Grilo CM, Lydecker JA, Fineberg SK, Moreno JO, Ivezaj V, Gueorguieva R. Naltrexone-Bupropion and Behavior Therapy, Alone and Combined, for Binge-Eating Disorder: Randomized Double-Blind Placebo-Controlled Trial. American Journal Of Psychiatry 2022, 179: 927-937. PMID: 36285406, PMCID: PMC9722598, DOI: 10.1176/appi.ajp.20220267.Peer-Reviewed Original ResearchMeSH KeywordsBehavior TherapyBinge-Eating DisorderBupropionDouble-Blind MethodFemaleHumansMaleMiddle AgedNaltrexoneObesityTreatment OutcomeWeight LossConceptsBehavioral weight loss therapyBinge-eating disorderPlacebo groupBupropion groupWeight lossRandomized double-blind placebo-controlled trialDouble-blind placebo-controlled trialLogistic regressionBinge-eating remissionPlacebo-controlled trialWeight loss therapyDouble-blind placeboSerious public health problemPublic health problemEvidence-based treatmentsRate of participantsBinge-eating frequencyBinge Eating DisorderMedical comorbiditiesRemission rateLoss therapyPercent weight lossMixed modelsFunctional impairmentSecondary measures
2021
Physical activity changes during behavioral weight loss treatment by Latinx patients with obesity with and without binge eating disorder
Grilo CM, Kerrigan SG, Lydecker JA, White MA. Physical activity changes during behavioral weight loss treatment by Latinx patients with obesity with and without binge eating disorder. Obesity 2021, 29: 2026-2034. PMID: 34582624, PMCID: PMC8612949, DOI: 10.1002/oby.23278.Peer-Reviewed Original ResearchMeSH KeywordsBinge-Eating DisorderCognitive Behavioral TherapyExerciseHumansObesityTreatment OutcomeWeight LossConceptsBehavioral weight loss treatmentWeight loss treatmentLatinx patientsPhysical activity changesBWL treatmentReduced depressionCommunity mental health centerWeight lossPA changePlacebo-controlled trialAddition of orlistatMental health centersActivity changesPrognostic significanceMedication conditionHealth centersLoss treatmentPatientsObesitySecondary analysisClinical settingBed statusBaselineTreatmentDepression
2020
Distinctiveness and significance of body dissatisfaction and overvaluation among Latinx/Hispanic and White men and women
Lydecker JA, Cotter EW, Grilo CM. Distinctiveness and significance of body dissatisfaction and overvaluation among Latinx/Hispanic and White men and women. International Journal Of Eating Disorders 2020, 54: 354-364. PMID: 33247450, PMCID: PMC7956228, DOI: 10.1002/eat.23413.Peer-Reviewed Original ResearchMeSH KeywordsAdultBinge-Eating DisorderBody DissatisfactionBody ImageBody WeightFemaleHispanic or LatinoHumansMaleConceptsOvervaluation of weightBody image constructsDisorder psychopathologyWeight-related variablesBody imageImage constructBinge-eating frequencyAssociation of dissatisfactionBody dissatisfactionOnline batteryPsychopathologyWhite individualsCultural variablesDissatisfactionMain effectOvervaluationDepressionImportant distinctionDistinctivenessConstructsIndividualsFurther researchHispanic individualsHispanic adultsParticipantsNaltrexone + Bupropion Combination for the Treatment of Binge-eating Disorder with Obesity: A Randomized, Controlled Pilot Study
Grilo CM, Lydecker JA, Morgan PT, Gueorguieva R. Naltrexone + Bupropion Combination for the Treatment of Binge-eating Disorder with Obesity: A Randomized, Controlled Pilot Study. Clinical Therapeutics 2020, 43: 112-122.e1. PMID: 33218742, PMCID: PMC7902424, DOI: 10.1016/j.clinthera.2020.10.010.Peer-Reviewed Original ResearchConceptsBinge-eating disorderEating-disorder psychopathologyPilot RCTTreatment of BEDOutcome time pointDouble-blind treatmentPercentage of patientsControlled Pilot StudyDiscontinuation of medicationTreatment of bingeEvidence-based treatmentsBinge-eating frequencyBupropion combinationAdult patientsAdverse eventsComorbid obesitySecondary outcomesPrimary outcomeAcute effectsFunctional impairmentPlaceboLong-term effectsPatientsMost outcomesObesityInterrater reliability of the Eating Disorder Examination among postbariatric patients
Wiedemann AA, Ivezaj V, Lawson JL, Lydecker JA, Cooper Z, Grilo CM. Interrater reliability of the Eating Disorder Examination among postbariatric patients. Surgery For Obesity And Related Diseases 2020, 16: 1988-1993. PMID: 32933867, PMCID: PMC7704555, DOI: 10.1016/j.soard.2020.07.032.Peer-Reviewed Original ResearchMeSH KeywordsAdultBariatric SurgeryBinge-Eating DisorderBulimiaFeeding and Eating DisordersHumansReproducibility of ResultsSurveys and QuestionnairesConceptsEating Disorder ExaminationIntraclass correlation coefficientEating-disorder psychopathologyBariatric surgerySurgery patientsInterrater reliabilityPostoperative bariatric surgery patientsDisorder ExaminationPostbariatric surgery patientsBariatric surgery patientsBariatric surgery sampleBinge-eating episodesSemistructured clinical interviewPostbariatric patientsBariatric patientsConsecutive seriesClinical assessmentSurgery samplesClinical InterviewPatientsSymptom presentationKappa agreementInitial evaluationEDE subscalesExpert ratersDoes Bariatric Binge‐Eating Size Matter? Conceptual Model and Empirical Support
Ivezaj V, Lydecker JA, Wiedemann AA, Duffy AJ, Grilo CM. Does Bariatric Binge‐Eating Size Matter? Conceptual Model and Empirical Support. Obesity 2020, 28: 1645-1651. PMID: 32729221, PMCID: PMC7484317, DOI: 10.1002/oby.22876.Peer-Reviewed Original ResearchConceptsEating Disorder Examination-Bariatric Surgery Version interviewBariatric surgeryEpisode groupBinge sizeFunctional impairmentDepressive symptomsNew classification systemMental health-related qualityLoss of controlPostsurgical bariatric patientsSurgery 6 monthsHealth-related qualityCross-sectional studyBinge-eating episodesQuality of lifeObjective binge-eating episodesBariatric patientsClinical outcomesEating Disorder PsychopathologyBinge-eating groupBinge eatingSurgeryClassification systemDistinct psychopathologySymptomsTesting the Validity and Clinical Utility of the Severity Specifiers for Binge-Eating Disorder for Predicting Treatment Outcomes
Lydecker JA, Ivezaj V, Grilo CM. Testing the Validity and Clinical Utility of the Severity Specifiers for Binge-Eating Disorder for Predicting Treatment Outcomes. Journal Of Consulting And Clinical Psychology 2020, 88: 172-178. PMID: 31894997, PMCID: PMC7286612, DOI: 10.1037/ccp0000464.Peer-Reviewed Original ResearchConceptsBinge-eating disorderCognitive behavioral therapyBehavioral weight lossSeverity specifiersSelf-report measuresTreatment-seeking individualsBinge-eating frequencyBinge Eating DisorderEating-disorder psychopathologyClinical utilityTreatment outcomesSeverity categoriesPredicting Treatment OutcomeWeight lossFuture researchMain effectDepression scoresStatistical ManualParticipantsTesting treatmentsMultimodal treatmentPharmacological treatmentTreatment responseMedical CenterLarge series