2023
Naltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trial
Grilo C, Lydecker J, Jastreboff A, Pittman B, McKee S. Naltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trial. Obesity 2023, 31: 2762-2773. PMID: 37751990, PMCID: PMC10600891, DOI: 10.1002/oby.23898.Peer-Reviewed Original ResearchConceptsNaltrexone/bupropionBinge-eating disorderObesity statusLogistic regressionWeight lossPlacebo-controlled trialWeight loss outcomesPrevalent psychiatric disordersEvidence-based treatmentsPost-treatment assessmentBinge-eating frequencyGreater percentage weight lossMedication outcomesRemission ratePharmacological optionsPlaceboBupropionPsychiatric disordersPercentage weight lossMixed modelsDisordersObesityPatientsSignificant reductionWeight reduction
2019
Patients' reasons for weight loss and their relations to clinical weight loss outcomes in a comprehensive lifestyle intervention
Boepple L, Cero I, Marek RJ, Coulon S, Lydecker JA, Brown JD, Malcolm R, O'Neil PM. Patients' reasons for weight loss and their relations to clinical weight loss outcomes in a comprehensive lifestyle intervention. Obesity Science & Practice 2019, 5: 548-554. PMID: 31890245, PMCID: PMC6934423, DOI: 10.1002/osp4.372.Peer-Reviewed Original ResearchWeight loss outcomesBody mass indexWeight change outcomesLoss outcomesWeight lossWhite patientsBlack patientsHigher body mass indexComprehensive lifestyle interventionWeight loss trajectoriesCertain patient groupsWeight loss treatmentWeight loss programLifestyle interventionPatient characteristicsMale patientsPatients' reasonsFemale patientsMass indexPercent weight lossLoss programPatient groupWorse outcomesDoctor's recommendationLoss treatment
2016
Loss-of-control eating following sleeve gastrectomy surgery
Ivezaj V, Kessler EE, Lydecker JA, Barnes RD, White MA, Grilo CM. Loss-of-control eating following sleeve gastrectomy surgery. Surgery For Obesity And Related Diseases 2016, 13: 392-398. PMID: 27913121, PMCID: PMC5357454, DOI: 10.1016/j.soard.2016.09.028.Peer-Reviewed Original ResearchConceptsSleeve gastrectomy surgeryGastrectomy surgeryWeight lossEating Disorder Examination-Bariatric Surgery VersionPoorer weight loss outcomesBED criteriaLower percent weight lossPoor weight lossWeight loss outcomesBody mass indexEating-disorder psychopathologyBinge-eating disorderRegular compensatory behaviorsCurrent mean ageUnited States METHODSBariatric surgeryPostoperative lossMass indexPercent weight lossMean ageMonths postsurgeryPoor outcomeLoss outcomesGreater severitySurgery