2011
Transcriptional programs in transient embryonic zones of the cerebral cortex defined by high-resolution mRNA sequencing
Ayoub AE, Oh S, Xie Y, Leng J, Cotney J, Dominguez MH, Noonan JP, Rakic P. Transcriptional programs in transient embryonic zones of the cerebral cortex defined by high-resolution mRNA sequencing. Proceedings Of The National Academy Of Sciences Of The United States Of America 2011, 108: 14950-14955. PMID: 21873192, PMCID: PMC3169109, DOI: 10.1073/pnas.1112213108.Peer-Reviewed Original ResearchConceptsTranscriptional programsHigh-resolution transcriptome mapDifferential transcriptome analysisStem cell maintenanceUnderlying transcriptional programsTransient embryonic zonesUncharacterized genesTranscriptome mapTranscriptome analysisEmbryonic mouse forebrainCell maintenanceGenetic programEmbryonic zonesMRNA sequencingCerebral cortexMolecular pathwaysStem cellsCell populationsMouse forebrainTranscriptsCortical plateSubventricular zoneGenesSequencingCortex
2006
Accelerated Evolution of Conserved Noncoding Sequences in Humans
Prabhakar S, Noonan JP, Pääbo S, Rubin EM. Accelerated Evolution of Conserved Noncoding Sequences in Humans. Science 2006, 314: 786-786. PMID: 17082449, DOI: 10.1126/science.1130738.Peer-Reviewed Original ResearchConceptsNoncoding sequencesNeuronal cell adhesionConserved Noncoding SequencesCis-regulatory changesHuman-specific substitutionsCell adhesionHuman regulatory sequencesPhenotypic divergenceAdaptive substitutionsGene regulationAccelerated evolutionIndependent evolutionRegulatory sequencesAdhesion genesHuman evolutionNeuronal phenotypeDifferent neuronal phenotypesGenesSequenceSimilar enrichmentBrain developmentChimpanzeesEvolutionMammalsAdhesion