2024
The relationship between gamma-band neural oscillations and language skills in youth with Autism Spectrum Disorder and their first-degree relatives
Arutiunian V, Santhosh M, Neuhaus E, Borland H, Tompkins C, Bernier R, Bookheimer S, Dapretto M, Gupta A, Jack A, Jeste S, McPartland J, Naples A, Van Horn J, Pelphrey K, Webb S. The relationship between gamma-band neural oscillations and language skills in youth with Autism Spectrum Disorder and their first-degree relatives. Molecular Autism 2024, 15: 19. PMID: 38711098, PMCID: PMC11075235, DOI: 10.1186/s13229-024-00598-1.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAutism Spectrum DisorderChildElectroencephalographyFamilyFemaleGamma RhythmHumansLanguageMaleSiblingsConceptsAutism spectrum disorderElevated gamma powerLow language skillsGamma powerResponses to speech stimuliLanguage skillsLanguage functionFirst-degree relativesSpectrum disorderClinical Evaluation of Language FundamentalsCo-occurring language impairmentSpeech stimuliCortical gamma-band oscillationsHigh gamma powerSex-balanced sampleGamma-band oscillationsSample of participantsNonverbal IQLanguage impairmentASD participantsTD controlsNeural profilesAutism phenotypeTD groupLanguage Fundamentals
2023
Frontal EEG alpha asymmetry in youth with autism: Sex differences and social–emotional correlates
Neuhaus E, Santhosh M, Kresse A, Aylward E, Bernier R, Bookheimer S, Jeste S, Jack A, McPartland J, Naples A, Van Horn J, Pelphrey K, Webb S, Network A. Frontal EEG alpha asymmetry in youth with autism: Sex differences and social–emotional correlates. Autism Research 2023, 16: 2364-2377. PMID: 37776030, PMCID: PMC10840952, DOI: 10.1002/aur.3032.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAutism Spectrum DisorderAutistic DisorderElectroencephalographyEmotionsFemaleHumansInfant, NewbornMaleSex CharacteristicsConceptsAutistic youthFrontal alpha powerMaternal depression historyIndividual differencesExternalizing behaviorsAlpha powerFrontal EEG alpha asymmetrySocial-emotional correlatesDepression historyEEG alpha asymmetryMental health behaviorsModel of riskAffective styleAutism featuresInternalizing symptomsASD diagnosisAlpha asymmetryAutistic femalesBehavioral indicesLevels of analysisAutistic malesEEG markersGroup differencesParticipant groupsASDDevelopment of peak alpha frequency reflects a distinct trajectory of neural maturation in autistic children
Finn C, Han G, Naples A, Wolf J, McPartland J. Development of peak alpha frequency reflects a distinct trajectory of neural maturation in autistic children. Autism Research 2023, 16: 2077-2089. PMID: 37638733, DOI: 10.1002/aur.3017.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAutism Spectrum DisorderAutistic DisorderChildCognitionElectroencephalographyHumansConceptsPeak alpha frequencyAutism spectrum disorderCognitive abilitiesAutistic childrenNonverbal IQNeural maturationSpectrum disorderTypical age-related increaseAlpha frequencyDifferent developmental trajectoriesDistinct trajectoriesSample of childrenCurrent study clarifiesDiagnostic groupsNeurotypical childrenNeurotypical controlsBehavioral measuresDevelopmental trajectoriesDiagnostic statusAge-related increaseFunction of ageIQEffect of ageBivariate relationsPrevious findings
2020
Neurologic Characterization of Craniosynostosis: Can Direct Brain Recordings Predict Language Development?
Wu R, Nie J, Abraham P, Halligan T, Gabrick K, Peck CJ, Sawh-Martinez R, Steinbacher DM, Alperovich M, McPartland J, Persing JA. Neurologic Characterization of Craniosynostosis: Can Direct Brain Recordings Predict Language Development? Journal Of Craniofacial Surgery 2020, 32: 78-82. PMID: 32941205, DOI: 10.1097/scs.0000000000007004.Peer-Reviewed Original ResearchMeSH KeywordsBrainChildCraniosynostosesElectroencephalographyFemaleHumansInfantLanguage DevelopmentMaleSpeechConceptsNeural responsesLanguage deficitsLanguage developmentERP assessmentMetopic patientsMismatch negativity waveLarger negative amplitudesLong-term cognitionLanguage achievementCognitive outcomesMMNBrain recordingsInfant developmentBayley ScalesNegative amplitudeBSID scoresEEG testingBSIDDeficitsElectroencephalogramNeurocognitionCognitionSpeechStimuliYears of ageN400 amplitude, latency, and variability reflect temporal integration of beat gesture and pitch accent during language processing
Morett LM, Landi N, Irwin J, McPartland JC. N400 amplitude, latency, and variability reflect temporal integration of beat gesture and pitch accent during language processing. Brain Research 2020, 1747: 147059. PMID: 32818527, PMCID: PMC7493208, DOI: 10.1016/j.brainres.2020.147059.Peer-Reviewed Original Research
2019
Autistic and alexithymic traits modulate distinct aspects of face perception
Desai A, Foss-Feig JH, Naples AJ, Coffman M, Trevisan DA, McPartland JC. Autistic and alexithymic traits modulate distinct aspects of face perception. Brain And Cognition 2019, 137: 103616. PMID: 31734588, PMCID: PMC6880874, DOI: 10.1016/j.bandc.2019.103616.Peer-Reviewed Original ResearchMeSH KeywordsAdultAffective SymptomsAutism Spectrum DisorderAutistic DisorderBrainElectroencephalographyEmotionsEvoked PotentialsFacial RecognitionFemaleHumansMaleYoung AdultConceptsAutism spectrum disorderEvent-related potentialsAlexithymic traitsAutistic traitsAtypical face processingEmotion recognition impairmentsEmotion decodingEmotion perceptionEmotional facesFace perceptionFace processingPerceptual processingNeural indicesNeutral facesStructural encodingRecognition impairmentEmotion recognitionERP componentsSpectrum disorderTemporal sensitivityGrouping factorsDistinct aspectsIndividual variabilityAlexithymiaDistinct contributions
2018
Reply to: Can the N170 Be Used as an Electrophysiological Biomarker Indexing Face Processing Difficulties in Autism Spectrum Disorder?
Kang E, McPartland JC, Keifer CM, Foss-Feig JH, Levy EJ, Lerner MD. Reply to: Can the N170 Be Used as an Electrophysiological Biomarker Indexing Face Processing Difficulties in Autism Spectrum Disorder? Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2018, 4: 324-325. PMID: 30391290, PMCID: PMC10026259, DOI: 10.1016/j.bpsc.2018.09.004.Commentaries, Editorials and LettersResting-state alpha power is selectively associated with autistic traits reflecting behavioral rigidity
Carter Leno V, Tomlinson SB, Chang SA, Naples AJ, McPartland JC. Resting-state alpha power is selectively associated with autistic traits reflecting behavioral rigidity. Scientific Reports 2018, 8: 11982. PMID: 30097597, PMCID: PMC6086866, DOI: 10.1038/s41598-018-30445-2.Peer-Reviewed Original ResearchNormalization of Speech Processing After Whole-Vault Cranioplasty in Sagittal Synostosis
Chuang C, Rolison M, Yang JF, Brooks ED, Hashim PW, Travieso R, Terner J, Steinbacher DM, Landi N, Stavropoulos KKM, Mayes LC, Persing JA, McPartland JC. Normalization of Speech Processing After Whole-Vault Cranioplasty in Sagittal Synostosis. Journal Of Craniofacial Surgery 2018, 29: 1132-1136. PMID: 29621073, DOI: 10.1097/scs.0000000000004474.Peer-Reviewed Original ResearchConceptsEvent-related potentialsMMN amplitudeWhole-vault cranioplastyNeural responsesLanguage processingAtypical neural responsesEarly language processingLanguage-related abilitiesSpeech soundsNeurocognitive studiesDifference waveSpeech processingFrontal electrodesMMNNegative deflectionLarge negative deflectionNeurocognitive outcomesGroup interactionNonsyndromic sagittal craniosynostosisMeasures analysisInteraction trendsProcessingPhonemesPoststimulus
2017
Modulation of reward in a live social context as revealed through interactive social neuroscience
Rolison MJ, Naples A, Rutherford HJV, McPartland J. Modulation of reward in a live social context as revealed through interactive social neuroscience. Social Neuroscience 2017, 13: 416-428. PMID: 28586261, PMCID: PMC6072262, DOI: 10.1080/17470919.2017.1339635.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderSocial neuroscience researchAutistic traitsLive interactionSocial neuroscienceReward processingNeuroscience researchReward processing deficitsReward processing mechanismsPathology of ASDModulation of rewardProcessing deficitsHuman partnerNeural sensitivityNeuroscience techniquesSpectrum disorderProcessing mechanismsMixed findingsSocial interactionDevelopmental disordersHuman competitorsEEG resultsSocial contextInconsistent findingsTreasure hunt gameSearching for Cross-Diagnostic Convergence: Neural Mechanisms Governing Excitation and Inhibition Balance in Schizophrenia and Autism Spectrum Disorders
Foss-Feig JH, Adkinson BD, Ji JL, Yang G, Srihari VH, McPartland JC, Krystal JH, Murray JD, Anticevic A. Searching for Cross-Diagnostic Convergence: Neural Mechanisms Governing Excitation and Inhibition Balance in Schizophrenia and Autism Spectrum Disorders. Biological Psychiatry 2017, 81: 848-861. PMID: 28434615, PMCID: PMC5436134, DOI: 10.1016/j.biopsych.2017.03.005.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAutism Spectrum DisorderBrainElectroencephalographyHumansMagnetic Resonance ImagingMagnetoencephalographyNeural InhibitionSchizophreniaConceptsAutism spectrum disorderSpectrum disorderFunctional magnetic resonance imagingRecent theoretical accountsEarly course schizophreniaNeurodevelopmental disordersPharmacological challenge studiesNeural correlatesNeuroscience literatureTheoretical accountsNeural circuitryTheoretical neuroscienceNoninvasive neuroimagingBehavioral dysfunctionFuture researchNeuropsychiatric conditionsComputational modelSchizophreniaProton magnetic resonance spectroscopyDisordersInhibition imbalanceMagnetic resonance imagingDistinct modalitiesPoint of convergenceInhibition balance
2016
Autistic traits modulate conscious and nonconscious face perception
Stavropoulos KK, Viktorinova M, Naples A, Foss-Feig J, McPartland JC. Autistic traits modulate conscious and nonconscious face perception. Social Neuroscience 2016, 13: 40-51. PMID: 27750521, PMCID: PMC6194504, DOI: 10.1080/17470919.2016.1248788.Peer-Reviewed Original ResearchConceptsEvent-related potentialsAutism spectrum disorderAutistic traitsEmotional facesFace perceptionAutism QuotientAQ scoresShorter N170 latenciesBroader autism phenotypeHigher AQ scoresAutistic-like traitsEmotion perceptionN170 latencyNonconscious perceptionNeural underpinningsERP componentsAutism phenotypeConscious awarenessSocial perceptionSocial impairmentNeural responsesSpectrum disorderP300 amplitudeCore featuresSubclinical levels
2015
Common and distinct modulation of electrophysiological indices of feedback processing by autistic and psychopathic traits
Leno V, Naples A, Cox A, Rutherford H, McPartland JC. Common and distinct modulation of electrophysiological indices of feedback processing by autistic and psychopathic traits. Social Neuroscience 2015, 11: 455-466. PMID: 26471250, PMCID: PMC4939614, DOI: 10.1080/17470919.2015.1108223.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderPsychopathic traitsFeedback processingEvent-related potentialsCommon brain mechanismsNonsocial feedbackNeural correlatesAutistic traitsAntisocial domainsBrain mechanismsElectrophysiological indicesSocial feedbackTask performanceBehavioral tasksNeural responsesSpectrum disorderSocial dysfunctionSocial behaviorManipulation domainSimilar difficultiesCurrent studyProcessingDistinct modulationTraitsSpecific formDiminished social reward anticipation in the broad autism phenotype as revealed by event-related brain potentials
Cox A, Kohls G, Naples AJ, Mukerji CE, Coffman MC, Rutherford HJ, Mayes LC, McPartland JC. Diminished social reward anticipation in the broad autism phenotype as revealed by event-related brain potentials. Social Cognitive And Affective Neuroscience 2015, 10: 1357-1364. PMID: 25752905, PMCID: PMC4590535, DOI: 10.1093/scan/nsv024.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderAutistic traitsReward anticipationReward responsivenessEvent-related brain potentialsSocial reward responsivenessSocial reward anticipationSocial motivation theoryBroader autism phenotypeSocial communication problemsIncentive delay taskMotivated attentionReward sensitivityBrain potentialsAutism phenotypeReward processingTypical functioningP3 responseP3 componentNeural responsesMotivation theorySpectrum disorderSocial informationSocial interactionPrior findings
2014
Brain Electrophysiology Reveals Intact Processing of Speech Sounds in Deformational Plagiocephaly
Hashim PW, Travieso R, Persing JA, Coffman M, Mukerji C, Naples A, Tillman RM, Terner J, Landi N, Patel A, Steinbacher D, Mayes L, McPartland J. Brain Electrophysiology Reveals Intact Processing of Speech Sounds in Deformational Plagiocephaly. Plastic & Reconstructive Surgery 2014, 133: 835e-841e. PMID: 24867743, DOI: 10.1097/prs.0000000000000219.Peer-Reviewed Original ResearchMeSH KeywordsAuditory PerceptionCerebral CortexElectroencephalographyEvoked Potentials, AuditoryFemaleHumansInfantPhoneticsPlagiocephaly, NonsynostoticSleepSupine PositionConceptsEvent-related potentialsEvent-related potential componentSpeech soundsAuditory event-related potential (ERP) componentsLong-term cognitive functioningPotential componentsPrior researchIntact processingNeural correlatesCognitive functioningAuditory perceptionTypical childrenAuditory processingNeural responsesBrain recordingsLong-term impairmentSubsequent functioningBrain electrophysiologyNormative expectationsDevelopmental scaleCortical activityCortical responsesBrain functionDeformational plagiocephalyCranial disorders
2013
Guidelines and Best Practices for Electrophysiological Data Collection, Analysis and Reporting in Autism
Webb SJ, Bernier R, Henderson HA, Johnson MH, Jones EJ, Lerner MD, McPartland JC, Nelson CA, Rojas DC, Townsend J, Westerfield M. Guidelines and Best Practices for Electrophysiological Data Collection, Analysis and Reporting in Autism. Journal Of Autism And Developmental Disorders 2013, 45: 425-443. PMID: 23975145, PMCID: PMC4141903, DOI: 10.1007/s10803-013-1916-6.Peer-Reviewed Original ResearchThe role of imitation in the observed heterogeneity in EEG mu rhythm in autism and typical development
Bernier R, Aaronson B, McPartland J. The role of imitation in the observed heterogeneity in EEG mu rhythm in autism and typical development. Brain And Cognition 2013, 82: 69-75. PMID: 23511847, DOI: 10.1016/j.bandc.2013.02.008.Peer-Reviewed Original ResearchConceptsMirror neuron system functionAutism spectrum disorderEEG mu rhythmImitation abilityMNS activityMu rhythmExecution/observation matching systemGoal-directed hand actionsMirror neuron systemObservation of actionsRole of imitationImitative skillsMNS functionCore deficitAction observationTypical developmentUniversal impairmentASD symptomsASD sampleHand actionsSocial deficitsSpectrum disorderSubset of childrenNeuron systemNormative patterns
2012
Multimodal emotion processing in autism spectrum disorders: An event-related potential study
Lerner MD, McPartland JC, Morris JP. Multimodal emotion processing in autism spectrum disorders: An event-related potential study. Developmental Cognitive Neuroscience 2012, 3: 11-21. PMID: 23245216, PMCID: PMC6987640, DOI: 10.1016/j.dcn.2012.08.005.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderInformation processing speedEmotion recognition performanceEvent-related potentialsEmotion processingEmotion recognitionProcessing speedSpectrum disorderEvent-related potential studyRecognition performanceMultimodal emotion processingEmotion identification taskVocal emotion recognitionCognitive processesIntact recognitionPerceptual modalitiesAdult facesNeural indicatorsERP componentsEmotion evaluationElectrophysiological markersBehavioral performanceIdentification taskPotential studiesIntervention targets
2011
Atypical neural specialization for social percepts in autism spectrum disorder
McPartland JC, Wu J, Bailey CA, Mayes LC, Schultz RT, Klin A. Atypical neural specialization for social percepts in autism spectrum disorder. Social Neuroscience 2011, 6: 436-451. PMID: 21777159, PMCID: PMC3204335, DOI: 10.1080/17470919.2011.586880.Peer-Reviewed Original ResearchMeSH KeywordsChildChild Development Disorders, PervasiveElectroencephalographyEvoked Potentials, VisualFaceFemaleHumansMaleVisual PerceptionConceptsNeural specializationNonsocial informationBehavioral performanceSocial informationSocial brain systemsSocial motivation hypothesisAtypical social developmentSpecificity of deficitsAberrant neural responsesEvent-related potentialsAutism spectrum disorderSocial perceptsFace processingCognitive abilitiesMotivation hypothesisBrain systemsElectrophysiological markersBrain responsesNeural responsesProcessing difficultiesSpectrum disorderStandardized measuresHuman faceAutismSpecific dysfunction
2010
Face-related ERPs are modulated by point of gaze
McPartland J, Cheung CH, Perszyk D, Mayes LC. Face-related ERPs are modulated by point of gaze. Neuropsychologia 2010, 48: 3657-3660. PMID: 20654637, PMCID: PMC2949471, DOI: 10.1016/j.neuropsychologia.2010.07.020.Peer-Reviewed Original ResearchConceptsFace processingFace-sensitive ERPsFace-sensitive componentLonger N170 latenciesEarly sensory componentsLower face regionPoint of gazeFace onsetN170 amplitudesN170 latencyFixation crosshairVisual attentionGaze fixationClinical populationsERPSensory componentFacial featuresFace regionAttentionProcessingEarly effectsElectrophysiological studiesGazeHemodynamic researchIsolated features