2020
Sex Differences in Functional Connectivity of the Salience, Default Mode, and Central Executive Networks in Youth with ASD
Lawrence KE, Hernandez LM, Bowman HC, Padgaonkar NT, Fuster E, Jack A, Aylward E, Gaab N, Van Horn JD, Bernier RA, Geschwind DH, McPartland JC, Nelson CA, Webb SJ, Pelphrey KA, Green SA, Bookheimer SY, Dapretto M, Consortium G. Sex Differences in Functional Connectivity of the Salience, Default Mode, and Central Executive Networks in Youth with ASD. Cerebral Cortex 2020, 30: 5107-5120. PMID: 32350530, PMCID: PMC7391269, DOI: 10.1093/cercor/bhaa105.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderCentral executive networkDefault mode networkFunctional connectivitySalience networkExecutive networkSymptomatology of ASDGreater functional connectivitySex-related biological factorsSample of girlsSN functional connectivitySex differencesAltered functional connectivityASD exhibitNeurotypical individualsNeurocognitive networksTypical developmentNeural mechanismsSpectrum disorderDefault modeMode networkParticipant sexMale samplesYouthGirlsImaging-genetics of sex differences in ASD: distinct effects of OXTR variants on brain connectivity
Hernandez LM, Lawrence KE, Padgaonkar NT, Inada M, Hoekstra JN, Lowe JK, Eilbott J, Jack A, Aylward E, Gaab N, Van Horn JD, Bernier RA, McPartland JC, Webb SJ, Pelphrey KA, Green SA, Geschwind DH, Bookheimer SY, Dapretto M. Imaging-genetics of sex differences in ASD: distinct effects of OXTR variants on brain connectivity. Translational Psychiatry 2020, 10: 82. PMID: 32127526, PMCID: PMC7054353, DOI: 10.1038/s41398-020-0750-9.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderNeurotypical malesOXTR variantsBrain connectivityNeurobiological mechanismsPrefrontal cortexFunctional connectivityNetwork resting-state functional connectivityManifestation of ASDReward-related brain regionsResting-state functional connectivityBrain areasGreater functional connectivityPrefrontal brain areasFemale protective effectSubcortical brain areasSpectrum disorderMotor learningOXTR geneDiagnosis relateHigh OXTRBrain regionsGenetic riskSubcortical regionsSex differences
2016
Autism Spectrum Disorder
McPartland J, Law K, Dawson G. Autism Spectrum Disorder. 2016, 124-130. DOI: 10.1016/b978-0-12-397045-9.00230-5.Peer-Reviewed Original ResearchAutism spectrum disorderSpectrum disorderAtypical social communicationPrevalent neurodevelopmental disorderRepetitive behavior patternsSensory interestsNeural changesASD researchSocial communicationBehavioral treatmentNeurodevelopmental disordersSex differencesBehavior patternsContent areasDisordersDiagnostic criteriaFuture progressProfessionalsClinical practiceResearch
2013
Sex Differences in Social Perception in Children with ASD
Coffman MC, Anderson LC, Naples AJ, McPartland JC. Sex Differences in Social Perception in Children with ASD. Journal Of Autism And Developmental Disorders 2013, 45: 589-599. PMID: 24293083, PMCID: PMC4039621, DOI: 10.1007/s10803-013-2006-5.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderSocial information processingFace perceptionEvent Related PotentialsInformation processingSex differencesSocial functionERP markersNeural correlatesASD literatureSocial perceptionFace responsesSpectrum disorderRelated potentialsSocial functioningBrain recordingsObserved sex differencesSymptom severityPerceptionUnderrepresentation of femalesCurrent studyInfluential differencesNeural phenotypesCorrelatesChildren