2024
Updated Analysis of Comparative Toxicity of Proton and Photon Radiation for Prostate Cancer
Yu J, DeStephano D, Jeffers B, Horowitz D, Soulos P, Gross C, Cheng S. Updated Analysis of Comparative Toxicity of Proton and Photon Radiation for Prostate Cancer. Journal Of Clinical Oncology 2024, 42: 1943-1952. PMID: 38507655, DOI: 10.1200/jco.23.01604.Peer-Reviewed Original ResearchIntensity-modulated radiation therapyProton beam therapyGU toxicityProstate cancerGI toxicityBenefits of proton beam therapyIntensity-modulated radiation therapy patientsPBT patientsLocalized prostate cancerTreatment-related toxicityComparison of GIStatistically significant differenceRadiation therapyBeam therapySEER-MedicareToxicity of protonProcedure codesComparative effectiveness studiesObservational studyPatientsSignificant differenceCancerMonthsComparing GIProstate
2020
Utilization of next-generation sequencing and associated systemic therapy initiation in metastatic prostate cancer.
Yang D, Leapman M, Gross C, Yu J. Utilization of next-generation sequencing and associated systemic therapy initiation in metastatic prostate cancer. Journal Of Clinical Oncology 2020, 38: e19308-e19308. DOI: 10.1200/jco.2020.38.15_suppl.e19308.Peer-Reviewed Original ResearchMetastatic prostate cancerSystemic therapy initiationTherapy initiationNGS test resultsNGS testingSystemic therapyMetastatic diagnosisNGS testsProstate cancerCommon systemic therapySystemic therapy selectionRetrospective observational studyNext-generation sequencing testDe-identified databaseMPC patientsTherapy startClinical outcomesMedian timeTherapy changesTreatment choiceObservational studyTherapy selectionGenomic classifierPatientsTherapy
2014
Considerations for Observational Research Using Large Data Sets in Radiation Oncology
Jagsi R, Bekelman J, Chen A, Chen R, Hoffman K, Shih Y, Smith B, Yu J. Considerations for Observational Research Using Large Data Sets in Radiation Oncology. International Journal Of Radiation Oncology • Biology • Physics 2014, 90: 11-24. PMID: 25195986, PMCID: PMC4159773, DOI: 10.1016/j.ijrobp.2014.05.013.Peer-Reviewed Original ResearchMeSH KeywordsChecklistComparative Effectiveness ResearchDatabases, FactualDiffusion of InnovationHealth Care CostsHealth Services ResearchHealth SurveysInsurance Claim ReviewMedicareNeoplasmsNomogramsObservational Studies as TopicProfessional PracticePropensity ScorePublication BiasRadiation OncologyRare DiseasesRegistriesResearch DesignSEER ProgramUnited StatesConceptsRadiation oncology communityRadiation oncologyObservational researchHealth services researchObservational studyWell-designed observational studiesOncology communityField of radiation oncologyHealth careServices researchEvaluate causalityObservational analysisData sourcesInternational Journal of Radiation OncologyMethodological expertiseRadiation oncology researchEvaluate evidenceRecognition of limitationsOncologyClinical trialsPotential data sourcesResearch questionsOncology researchHealthMethodological considerationsStereotactic body radiosurgery versus intensity modulated radiotherapy for prostate cancer: Comparison of toxicity.
Yu J, Cramer L, Herrin J, Soulos P, Potosky A, Gross C. Stereotactic body radiosurgery versus intensity modulated radiotherapy for prostate cancer: Comparison of toxicity. Journal Of Clinical Oncology 2014, 32: 89-89. DOI: 10.1200/jco.2014.32.4_suppl.89.Peer-Reviewed Original ResearchStereotactic body radiosurgeryGU complicationsProstate cancerSBRT patientsIMRT patientsGU toxicityRate of complicationsRetrospective observational studyBladder outlet obstructionHigh cure ratesRandom-effects modelCost of treatmentOutlet obstructionUrinary incontinenceTreatment initiationRetrospective studyCure rateUrethral strictureDiagnosis codesPrimary treatmentObservational studyRadiation therapyMean costMedicare beneficiariesPatients