1989
Effects of corticosteroid hormones on the electrophysiology of rat distal colon: implications for Na+ and K+ transport.
Binder H, McGlone F, Sandle G. Effects of corticosteroid hormones on the electrophysiology of rat distal colon: implications for Na+ and K+ transport. The Journal Of Physiology 1989, 410: 425-441. PMID: 2795485, PMCID: PMC1190488, DOI: 10.1113/jphysiol.1989.sp017542.Peer-Reviewed Original ResearchConceptsRU 28362Rat distal colonDistal colonCorticosteroid hormonesChannel blocker tetraethylammonium chlorideEffects of aldosteroneCase of aldosteroneTypes of receptorsChannel blocker amilorideMineralocorticoid receptorEpithelial responseAldosteroneControl animalsGlucocorticoid receptorPattern of responseConventional microelectrodesCell membrane changesTetraethylammonium chlorideCorticosteroidsReceptorsSpironolactoneColonDexamethasoneHormonePotency
1986
Demonstration of Specific High Affinity Receptors for Aldosterone in Cytosol of Rat Colon*
BINDER H, WHITE A, WHITING D, HAYSLETT J. Demonstration of Specific High Affinity Receptors for Aldosterone in Cytosol of Rat Colon*. Endocrinology 1986, 118: 628-631. PMID: 2935388, DOI: 10.1210/endo-118-2-628.Peer-Reviewed Original ResearchConceptsRat distal colonSpecific high-affinity receptorsDistal colonHigh-affinity receptorFmol/Affinity receptorAction of aldosteroneGlucocorticoid receptor systemHigh-affinity binding proteinsRU 28362Competitive binding studiesScatchard plot analysisAldosteroneHigh affinity receptor proteinAldosterone bindingAffinity sitesRat colonGlucocorticoid receptorSpecific high affinity receptor proteinColonReceptor systemDirect actionCytosolic receptorReceptorsLow affinity sites