2001
Na+-dependent fluid absorption in intact perfused rat colonic crypts
Geibel J, Rajendran V, Binder H. Na+-dependent fluid absorption in intact perfused rat colonic crypts. Gastroenterology 2001, 120: 144-150. PMID: 11208723, DOI: 10.1053/gast.2001.20890.Peer-Reviewed Original ResearchMeSH Keywords4,4'-Diisothiocyanostilbene-2,2'-Disulfonic AcidAnimalsBicarbonatesChloridesColonGanglionic StimulantsGlutamatesIn Vitro TechniquesIntestinal AbsorptionInulinIsotonic SolutionsMalePerfusionQuaternary Ammonium CompoundsRatsRats, Sprague-DawleyRinger's SolutionSodiumSodium-Hydrogen ExchangersTritiumConceptsNet fluid absorptionRat colonic cryptsCl- channel blockerFluid absorptionNeurohumoral stimulationChannel blockersColonic cryptsLumen ClAbsorptive processesInhibitor of NaCl(-) secretionAbstractTextCrypt cellsExchange inhibitorMicroperfusion techniqueFluid secretionL DIDSAmiloride analoguesMammalian colonSecretionAnion exchange inhibitorCryptsSignificant increaseAIMSSecretory process
1986
Augmentation of neutral sodium chloride absorption by increased flow rate in rat ileum in vivo.
Harris M, Dobbins J, Binder H. Augmentation of neutral sodium chloride absorption by increased flow rate in rat ileum in vivo. Journal Of Clinical Investigation 1986, 78: 431-438. PMID: 3734099, PMCID: PMC423573, DOI: 10.1172/jci112594.Peer-Reviewed Original ResearchConceptsNeutral sodium chloride absorptionSodium chloride absorptionRat ileumChloride absorptionIntraluminal volumeAddition of furosemideTransmural potential differenceSingle-pass perfusionOutflow tubingIntraluminal pressureSodium absorptionPerfusion mediumIntact animalsElectrolyte absorptionIleumElectrolyte transportRinger's solutionIncreased ratesPerfusion rateRemoval of sodiumStepwise increaseMinimal changesSeparate experimentsUnstirred layer thicknessSolute absorption