1985
Evidence that aldosterone influences transport in target tissues by dissimilar mechanisms
Hirsch D, Pace P, Binder H, Hayslett J. Evidence that aldosterone influences transport in target tissues by dissimilar mechanisms. American Journal Of Physiology 1985, 248: f507-f512. PMID: 3985157, DOI: 10.1152/ajprenal.1985.248.4.f507.Peer-Reviewed Original ResearchMeSH KeywordsAldosteroneAmilorideAnimalsBiological TransportBiomechanical PhenomenaChloridesColonHyperaldosteronismMalePhysiologyPotassiumRatsRats, Inbred StrainsSodiumConceptsProximal colonDistal colonSodium absorptionEffects of hyperaldosteronismSodium-free dietTarget tissuesAction of aldosteroneNet sodium absorptionRat proximal colonTransmural potential differenceAldosterone influencesHormone-induced changesSecondary hyperaldosteronismPotassium secretionControl animalsNet sodiumColonExperimental animalsHyperaldosteronismAldosteroneSodium transportProximal portionElectrolyte transportMicroA xTissue
1982
Mechanism of potassium adaptation
Hayslett J, Binder H. Mechanism of potassium adaptation. American Journal Of Physiology 1982, 243: f103-f112. PMID: 7051849, DOI: 10.1152/ajprenal.1982.243.2.f103.Peer-Reviewed Original ResearchConceptsPotassium secretionPotassium adaptationChronic renal insufficiencyNa-K-ATPase activityAdministration of glucocorticoidsPotassium loadingNa-K-ATPaseTransepithelial potential differenceRenal insufficiencyPotassium excretionColonic mucosaExcretory loadDietary potassium loadingDistal nephronLarge intestinePotassium homeostasisDietary loadingElevated levelsPotassium pumpBasolateral portionEpitheliumCellular changesDistal portionSecretionBasolateral cell membrane