1999
Stimulation of Sodium Chloride Absorption from Secreting Rat Colon by Short-Chain Fatty Acids
Krishnan S, Ramakrishna BS, Binder H. Stimulation of Sodium Chloride Absorption from Secreting Rat Colon by Short-Chain Fatty Acids. Digestive Diseases And Sciences 1999, 44: 1924-1930. PMID: 10505736, DOI: 10.1023/a:1018871412748.Peer-Reviewed Original ResearchConceptsShort-chain fatty acidsNa absorptionNaCl absorptionControl normal mucosaNet Cl secretionRat distal colonSodium chloride absorptionPresence of SCFAEffect of butyrateElectroneutral NaCl absorptionVoltage-clamp conditionsFatty acidsDistal colonNormal mucosaRat colonAbsorptive pathwaysCl(-) secretionChloride absorptionColonCAMP elevationSCFAMucosaSecretagoguesAdenosine monophosphateSecretion
1990
Characterization of butyrate-dependent electroneutral Na-Cl absorption in the rat distal colon
Binder H, Mehta P. Characterization of butyrate-dependent electroneutral Na-Cl absorption in the rat distal colon. Pflügers Archiv - European Journal Of Physiology 1990, 417: 365-369. PMID: 2080102, DOI: 10.1007/bf00370654.Peer-Reviewed Original ResearchConceptsCl absorptionDistal colonCyclic adenosine monophosphateMucosal cyclic adenosine monophosphateElectroneutral NaElectroneutral sodium chloride absorptionAdenosine monophosphateRat distal colonSodium chloride absorptionRinger's solutionNa-H exchangeNet Cl- absorptionCyclic AMP inhibitionNet NaColonRatsInhibitionAMP inhibitionRecent studies
1987
Mechanism of electroneutral sodium chloride absorption in distal colon of the rat
Binder H, Foster E, Budinger M, Hayslett J. Mechanism of electroneutral sodium chloride absorption in distal colon of the rat. Gastroenterology 1987, 93: 449-455. PMID: 3609655, DOI: 10.1016/0016-5085(87)90905-x.Peer-Reviewed Original ResearchConceptsSodium chloride absorptionElectroneutral sodium chloride absorptionNet sodium absorptionNet chloride absorptionDistal colonChloride absorptionSodium absorptionRat distal colonSodium chloride cotransportVoltage-clamp conditionsMM furosemideMM amilorideMucosal bathing solutionChloride transportClamp conditionsColonBathing solutionRatsElectrogenic sodiumMechanism of sodiumAmilorideSodiumAbsence of potassiumCotransportMucosa
1986
Ion transport in proximal colon of the rat. Sodium depletion stimulates neutral sodium chloride absorption.
Foster E, Budinger M, Hayslett J, Binder H. Ion transport in proximal colon of the rat. Sodium depletion stimulates neutral sodium chloride absorption. Journal Of Clinical Investigation 1986, 77: 228-235. PMID: 2418060, PMCID: PMC423331, DOI: 10.1172/jci112281.Peer-Reviewed Original ResearchMeSH Keywords4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid4,4'-Diisothiocyanostilbene-2,2'-Disulfonic AcidAcetazolamideAmilorideAnimalsBiological Transport, ActiveColonHyperaldosteronismIntestinal AbsorptionIntestinal MucosaIon ChannelsMaleRatsRats, Inbred StrainsSodium ChlorideTheophyllineConceptsMu eq/hSodium-hydrogen exchangeProximal colonSodium depletionSodium absorptionDistal colonNeutral sodium chloride absorptionDistal segmentsAmiloride-sensitive sodium absorptionNet sodium absorptionSodium-depleted ratsRat distal colonSodium chloride absorptionNeutral sodium absorptionHydrogen ion secretionSecondary hyperaldosteronismParallel fallRat colonControl groupMM amilorideMucosal amilorideJNanetColonIon secretionChloride absorption
1983
Role of calcium in the regulation of colonic secretion in the rat
Zimmerman T, Dobbins J, Binder H. Role of calcium in the regulation of colonic secretion in the rat. American Journal Of Physiology 1983, 244: g552-g560. PMID: 6133455, DOI: 10.1152/ajpgi.1983.244.5.g552.Peer-Reviewed Original ResearchConceptsSerosal calciumRole of calciumExtracellular calciumElectrolyte transportNeutral sodium chloride absorptionEffect of bethanecholEffect of theophyllineMuscarinic cholinergic agonistNet sodium absorptionSodium chloride absorptionNet chloride absorptionCalcium-free mediumNeutral NaCl absorptionColonic secretionCholinergic agonistsIntracellular calciumBethanecholNet sodiumRat colonChloride secretionJNanetSodium absorptionChloride absorptionJClnetNaCl absorptionCyclic Adenosine Monophosphate Stimulates Active Potassium Secretion in the Rat Colon
Foster E, Sandle G, Hayslett J, Binder H. Cyclic Adenosine Monophosphate Stimulates Active Potassium Secretion in the Rat Colon. Gastroenterology 1983, 84: 324-330. PMID: 6293907, DOI: 10.1016/s0016-5085(83)80130-9.Peer-Reviewed Original ResearchConceptsActive potassium secretionNormal potassium dietPotassium secretionNet potassium secretionPotassium dietCyclic adenosine monophosphateDibutyryl cyclic adenosine monophosphateRat colonAdenosine monophosphatePotassium-loaded animalsCholinergic muscarinic agonistHigh potassium dietProximal colonic mucosaCalcium-dependent processesX cm2
1975
Effect of Shigella Enterotoxin on Electrolyte Transport in Rabbit Ileum
Donowitz M, Keusch G, Binder H. Effect of Shigella Enterotoxin on Electrolyte Transport in Rabbit Ileum. Gastroenterology 1975, 69: 1230-1237. PMID: 172398, DOI: 10.1016/s0016-5085(19)32315-7.Peer-Reviewed Original ResearchConceptsCyclic adenosine monophosphate levelsRabbit ileal mucosaIntestinal secretionShigella enterotoxinAdenosine monophosphate levelsElectrolyte secretionControl mucosaIleal mucosaCholera enterotoxinMonophosphate levelsNet sodium absorptionNet sodium secretionIntracellular cyclic adenosine monophosphate (cAMP) levelsAdenosine monophosphateEscherichia coli enterotoxinIntestinal waterUssing chambersRabbit ileumCyclic adenosine monophosphateSodium secretionMucosaSmall intestineSodium absorptionControl tissuesElectrolyte accumulation