1989
Effects of corticosteroid hormones on the electrophysiology of rat distal colon: implications for Na+ and K+ transport.
Binder H, McGlone F, Sandle G. Effects of corticosteroid hormones on the electrophysiology of rat distal colon: implications for Na+ and K+ transport. The Journal Of Physiology 1989, 410: 425-441. PMID: 2795485, PMCID: PMC1190488, DOI: 10.1113/jphysiol.1989.sp017542.Peer-Reviewed Original ResearchConceptsRU 28362Rat distal colonDistal colonCorticosteroid hormonesChannel blocker tetraethylammonium chlorideEffects of aldosteroneCase of aldosteroneTypes of receptorsChannel blocker amilorideMineralocorticoid receptorEpithelial responseAldosteroneControl animalsGlucocorticoid receptorPattern of responseConventional microelectrodesCell membrane changesTetraethylammonium chlorideCorticosteroidsReceptorsSpironolactoneColonDexamethasoneHormonePotency
1985
Evidence that aldosterone influences transport in target tissues by dissimilar mechanisms
Hirsch D, Pace P, Binder H, Hayslett J. Evidence that aldosterone influences transport in target tissues by dissimilar mechanisms. American Journal Of Physiology 1985, 248: f507-f512. PMID: 3985157, DOI: 10.1152/ajprenal.1985.248.4.f507.Peer-Reviewed Original ResearchConceptsProximal colonDistal colonSodium absorptionEffects of hyperaldosteronismSodium-free dietTarget tissuesAction of aldosteroneNet sodium absorptionRat proximal colonTransmural potential differenceAldosterone influencesHormone-induced changesSecondary hyperaldosteronismPotassium secretionControl animalsNet sodiumColonExperimental animalsHyperaldosteronismAldosteroneSodium transportProximal portionElectrolyte transportMicroA xTissue
1982
Demonstration of net potassium absorption in mammalian colon
Hayslett J, Halevy J, Pace P, Binder H. Demonstration of net potassium absorption in mammalian colon. American Journal Of Physiology 1982, 242: g209-g214. PMID: 7065184, DOI: 10.1152/ajpgi.1982.242.3.g209.Peer-Reviewed Original ResearchConceptsPotassium-deficient animalsNet potassium absorptionNet potassium secretionPlasma potassium levelsPotassium secretionNet potassium movementPotassium levelsPotassium-loaded animalsPotassium movementMammalian colonColon of controlLow-sodium solutionDistal colonPotassium absorptionSodium solutionControl animalsProximal segmentDistal lumensIntestinal transportNet secretionColonCarrier-mediated processSecretionAdditional studiesVivo studies