1998
Differential localization of colonic H+-K+-ATPase isoforms in surface and crypt cells
Rajendran V, Singh S, Geibel J, Binder H. Differential localization of colonic H+-K+-ATPase isoforms in surface and crypt cells. American Journal Of Physiology 1998, 274: g424-g429. PMID: 9486199, DOI: 10.1152/ajpgi.1998.274.2.g424.Peer-Reviewed Original ResearchConceptsCrypt cellsColonic cryptsRat distal colonSurface cellsSurface epithelial cellsATPase isoformsOuabain-insensitive componentApical membraneDistal colonAcid loadDependent intracellularEpithelial cellsATPase activityCryptsDifferential localizationOuabainATPase alpha subunitCellsAlpha subunitCompelling evidenceIsoformsColonActivityRecovery
1991
Apical membrane localization of ouabain-sensitive K(+)-activated ATPase activities in rat distal colon
Del Castillo J, Rajendran V, Binder H. Apical membrane localization of ouabain-sensitive K(+)-activated ATPase activities in rat distal colon. American Journal Of Physiology 1991, 261: g1005-g1011. PMID: 1837421, DOI: 10.1152/ajpgi.1991.261.6.g1005.Peer-Reviewed Original ResearchConceptsRat distal colonOuabain-insensitive fractionDistal colonOuabain-sensitive fractionOuabain-insensitive componentHalf-maximal concentrationApical membraneATPase activityColonic mucosaProximal colonColonActivation curveAbsorptive processesAdenosinetriphosphatase activityApical membrane localizationBasolateral membraneHomogenatesN-ethylmaleimideMucosaActivityOmeprazole