2019
Let it be: mindful acceptance down-regulates pain and negative emotion
Kober H, Buhle J, Weber J, Ochsner KN, Wager TD. Let it be: mindful acceptance down-regulates pain and negative emotion. Social Cognitive And Affective Neuroscience 2019, 14: 1147-1158. PMID: 31989171, PMCID: PMC7057281, DOI: 10.1093/scan/nsz104.Peer-Reviewed Original ResearchConceptsMindful acceptanceEmotion regulation strategiesCognitive control systemPrefrontal control systemsMeditation-naïve participantsSelf-report measuresKinds of stimuliEmotion regulationNeutral imagesNegative emotionsAmygdala responseMindfulness trainingNegative affectAffective significanceEmotional intensityRegulation strategiesBrain processesNegative imageInitial appraisalEmotionsLateral pain systemPain systemStimuliParticipantsChronic pain
2018
Training in cognitive strategies reduces eating and improves food choice
Boswell RG, Sun W, Suzuki S, Kober H. Training in cognitive strategies reduces eating and improves food choice. Proceedings Of The National Academy Of Sciences Of The United States Of America 2018, 115: e11238-e11247. PMID: 30420496, PMCID: PMC6275472, DOI: 10.1073/pnas.1717092115.Peer-Reviewed Original ResearchConceptsCognitive strategiesFood valuationBrief trainingUnhealthy foodsCognitive regulation strategiesFood choicesEffects of framingRegulation strategiesStudy 5Study 1Study 3Unhealthy eatingStudy 6Training componentHealthy food choicesNegative consequencesPositive benefitsCravingHealthy foodsTrainingClinical implicationsPrior workIndividualsImplicationsEating
2010
Prefrontal–striatal pathway underlies cognitive regulation of craving
Kober H, Mende-Siedlecki P, Kross EF, Weber J, Mischel W, Hart CL, Ochsner KN. Prefrontal–striatal pathway underlies cognitive regulation of craving. Proceedings Of The National Academy Of Sciences Of The United States Of America 2010, 107: 14811-14816. PMID: 20679212, PMCID: PMC2930456, DOI: 10.1073/pnas.1007779107.Peer-Reviewed Original ResearchConceptsSubstance use disordersUse disordersPrefrontal cortexVentral tegmental areaSubstance-dependent populationsMore effective treatmentsLong-term consumptionDorsolateral prefrontal cortex activityPrefrontal cortex activityCigarette smokersTegmental areaVentrolateral prefrontal cortexVentral striatum activityVentral striatal activitySubgenual cingulateEffective treatmentLateral prefrontal cortexStriatal activityVentral striatumCortex activityFunctional imagingPhysical healthStriatum activityNeural activityCortex