2023
Adaptive evaluation of mHealth and conventional adherence support interventions to optimize outcomes with new treatment regimens for drug-resistant tuberculosis and HIV in South Africa (ADAP-TIV): study protocol for an adaptive randomized controlled trial
Ross J, Perumal R, Wolf A, Zulu M, Guzman K, Seepamore B, Reis K, Nyilana H, Hlathi S, Narasimmulu R, Cheung Y, Amico K, Friedland G, Daftary A, Zelnick J, Naidoo K, O’Donnell M. Adaptive evaluation of mHealth and conventional adherence support interventions to optimize outcomes with new treatment regimens for drug-resistant tuberculosis and HIV in South Africa (ADAP-TIV): study protocol for an adaptive randomized controlled trial. Trials 2023, 24: 776. PMID: 38037105, PMCID: PMC10691086, DOI: 10.1186/s13063-023-07520-9.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntitubercular AgentsHIV InfectionsHumansProspective StudiesRandomized Controlled Trials as TopicSouth AfricaTreatment OutcomeTuberculosis, Multidrug-ResistantConceptsMultidrug-resistant tuberculosisAdherence support interventionsAntiretroviral therapyTreatment regimensAdherence supportPrimary outcomeTreatment supportPsychosocial supportMDR-TB treatment regimensUndetectable HIV viral loadSupport interventionsIntegrase strand transfer inhibitorsAdherence support strategiesComposite clinical outcomeMDR-TB regimensNegative TB culturesCombination antiretroviral therapyComposite primary outcomeHIV treatment outcomesHIV viral loadDrug-resistant tuberculosisStandard of careNew treatment regimensDifferentiated service deliveryStrand transfer inhibitors
2010
Opportunities afforded by new drugs for tuberculosis
Churchyard GJ, Friedland G, Fielding K, Nardell E. Opportunities afforded by new drugs for tuberculosis. The Lancet Infectious Diseases 2010, 10: 368-369. PMID: 20510274, DOI: 10.1016/s1473-3099(10)70095-5.Peer-Reviewed Original ResearchAdolescentAdultAntitubercular AgentsBiomedical ResearchChildChild, PreschoolHumansLatent TuberculosisRandomized Controlled Trials as TopicTuberculosis, Multidrug-ResistantYoung Adult