2024
Integrating methadone into primary care settings in Ukraine: effects on provider stigma and knowledge
Bromberg D, Machavariani E, Madden L, Dumchev K, LaMonaca K, Earnshaw V, Pykalo I, Filippovych M, Haddad M, Dvoriak S, Altice F. Integrating methadone into primary care settings in Ukraine: effects on provider stigma and knowledge. Journal Of The International AIDS Society 2024, 27: e26202. PMID: 38379179, PMCID: PMC10879646, DOI: 10.1002/jia2.26202.Peer-Reviewed Original ResearchConceptsPrimary care clinicsStigma reduction interventionsOpioid agonist therapyClinicians' attitudesStigma constructsHIV preventionReduction interventionsEvidence-based HIV preventionCluster randomized controlled trialEvidence-based carePrimary care settingIntegrated care sitesDirect providersRandomized controlled trialsProvider stigmaCare clinicsCare sitesHIV careCare settingsHealth outcomesClinical staffSubstance use disordersLinear mixed-effects modelsTreatment continuumImprove attitudesStalled Scale-Up of Opioid Agonist Therapies for HIV Prevention in Kazakhstan: History, Policy, and Recommendations for Change
Liberman A, Ivasiy R, Altice F, Bromberg D, Ibragimova O, Seksenova Z, Madden L, Primbetova S, Terlikbayeva A. Stalled Scale-Up of Opioid Agonist Therapies for HIV Prevention in Kazakhstan: History, Policy, and Recommendations for Change. Journal Of Illicit Economies And Development 2024, 5: 69-77. DOI: 10.31389/jied.208.Peer-Reviewed Original Research
2023
Global HIV control: is the glass half empty or half full?
Nachega J, Musoke P, Kilmarx P, Gandhi M, Grinsztejn B, Pozniak A, Rawat A, Wilson L, Mills E, Altice F, Mellors J, Quinn T. Global HIV control: is the glass half empty or half full? The Lancet HIV 2023, 10: e617-e622. PMID: 37506723, PMCID: PMC10733629, DOI: 10.1016/s2352-3018(23)00150-9.Peer-Reviewed Original ResearchClinic-Integrated Smartphone App (JomPrEP) to Improve Uptake of HIV Testing and Pre-exposure Prophylaxis Among Men Who Have Sex With Men in Malaysia: Mixed Methods Evaluation of Usability and Acceptability
Shrestha R, Altice F, Khati A, Azwa I, Gautam K, Gupta S, Sullivan P, Ni Z, Kamarulzaman A, Phiphatkunarnon P, Wickersham J. Clinic-Integrated Smartphone App (JomPrEP) to Improve Uptake of HIV Testing and Pre-exposure Prophylaxis Among Men Who Have Sex With Men in Malaysia: Mixed Methods Evaluation of Usability and Acceptability. JMIR MHealth And UHealth 2023, 11: e44468. PMID: 36795465, PMCID: PMC9982718, DOI: 10.2196/44468.Peer-Reviewed Original ResearchConceptsHIV prevention servicesINTERNATIONAL REGISTERED REPORT IDENTIFIERPrevention servicesMean ageHIV preventionPre-exposure prophylaxisHIV prevention outcomesHIV self-testing (HIVST) kitsParticipants' mean ageSelf-testing kitsHealth care settingsMobile health platformMalaysian MSMMixed-methods evaluationHIV testingCare settingsLocal clinicSystem Usability ScalePrevention outcomesDays of testingMSMSmartphone appPrEPHIVMean score
2022
Clinic-Integrated Mobile Health Intervention (“JomPrEP” App) to Improve Uptake of HIV Testing and Pre-exposure Prophylaxis Among Men Who Have Sex With Men in Malaysia: Protocol for an Intervention Development and Multiphase Trial
Shrestha R, Wickersham J, Khati A, Azwa I, Ni Z, Kamarulzaman A, Sullivan P, Jadkarim L, Eger W, Gautam K, Altice F. Clinic-Integrated Mobile Health Intervention (“JomPrEP” App) to Improve Uptake of HIV Testing and Pre-exposure Prophylaxis Among Men Who Have Sex With Men in Malaysia: Protocol for an Intervention Development and Multiphase Trial. JMIR Research Protocols 2022, 11: e43318. PMID: 36542425, PMCID: PMC9813821, DOI: 10.2196/43318.Peer-Reviewed Original ResearchINTERNATIONAL REGISTERED REPORT IDENTIFIERPre-exposure prophylaxisHIV prevention servicesHIV testingMalaysian MSMPhase IHIV preventionPrevention servicesLarge-scale efficacy trialsHIV prevention resourcesMobile health interventionsHIV prevention effortsCare delivery servicesHealth care delivery servicesMultiphase trialPrEP servicesMiddle-income countriesHIV epidemicEfficacy trialsTrial designPrevention strategiesEntrenched stigmaHealth outcomesReal-world settingHealth interventionsNurse Practitioner–Led Integrated Rapid Access to HIV Prevention for People Who Inject Drugs (iRaPID): Protocol for a Pilot Randomized Controlled Trial
Khati A, Altice FL, Vlahov D, Eger WH, Lee J, Bohonnon T, Wickersham JA, Maviglia F, Copenhaver N, Shrestha R. Nurse Practitioner–Led Integrated Rapid Access to HIV Prevention for People Who Inject Drugs (iRaPID): Protocol for a Pilot Randomized Controlled Trial. JMIR Research Protocols 2022, 11: e42585. PMID: 36222826, PMCID: PMC9597427, DOI: 10.2196/42585.Peer-Reviewed Original ResearchINTERNATIONAL REGISTERED REPORT IDENTIFIERSame-day PrEPHIV prevention programsPreliminary efficacyTrial designReal-world settingPrevention programsPre-exposure prophylaxis uptakePilot studyProspective pilot studySignificant public health concernOpioid use disorderHIV prevention strategiesHepatitis C virusOutbreak of HIVEvidence-based preventionPublic health concernInstitutional review boardMOUD initiationControlled TrialsPilot RCTC virusOpioid epidemicHIV preventionNurse practitionersMobile Health Technology Use and the Acceptability of an mHealth Platform for HIV Prevention Among Men Who Have Sex With Men in Malaysia: Cross-sectional Respondent-Driven Sampling Survey
Shrestha R, Maviglia F, Altice FL, DiDomizio E, Khati A, Mistler C, Azwa I, Kamarulzaman A, Halim MAA, Wickersham JA. Mobile Health Technology Use and the Acceptability of an mHealth Platform for HIV Prevention Among Men Who Have Sex With Men in Malaysia: Cross-sectional Respondent-Driven Sampling Survey. Journal Of Medical Internet Research 2022, 24: e36917. PMID: 35877172, PMCID: PMC9361153, DOI: 10.2196/36917.Peer-Reviewed Original ResearchConceptsHIV prevention informationHIV preventionDrug usePrevention informationMalaysian menMHealth platformHIV risk-related behaviorsHIV prevention toolHIV prevention servicesSexual activityReceptive anal sexMobile health interventionsHIV prevention effortsUse of mHealthIllicit drug useSexualized drug useCross-sectional surveyAcceptability of mHealthHealth technology useSelf-administered questionnaireRespondent-driven samplingHealth-related informationSuboptimal engagementDearth of evidencePrevention servicesMobile Technology Use and Acceptability of mHealth for HIV Prevention Among Men Who Have Sex With Men in Malaysia
Maviglia F, Shrestha R, Altice F, DiDomizio L, Khati A, Mistler C, Azwa I, Kamarulzaman A, Halim M, Wickersham J. Mobile Technology Use and Acceptability of mHealth for HIV Prevention Among Men Who Have Sex With Men in Malaysia. Iproceedings 2022, 8: e39303. DOI: 10.2196/39303.Peer-Reviewed Original ResearchAcceptability of mHealthHIV preventionMalaysian MSMHIV risk-related behaviorsHIV prevention needsHIV prevention servicesHIV prevention informationHIV prevention effortsCross-sectional surveyRespondent-driven samplingHealth-related informationSuboptimal engagementPrevention needsDearth of evidencePrevention servicesMHealth interventionsDrug useKey populationsMHealth strategiesRisk-related behaviorsDrug cravingPrevention informationPrevention effortsParticipant demographicsPreventionA PrEP Demonstration Project Using eHealth and Community Outreach to Justice-Involved Cisgender Women and Their Risk Networks
Meyer JP, Price CR, Ye Y, Qin Y, Tracey D, Demidont AC, Melbourne K, Altice FL. A PrEP Demonstration Project Using eHealth and Community Outreach to Justice-Involved Cisgender Women and Their Risk Networks. AIDS And Behavior 2022, 26: 3807-3817. PMID: 35672552, DOI: 10.1007/s10461-022-03709-2.Peer-Reviewed Original ResearchConceptsTDF/FTCPrEP care continuumPre-exposure prophylaxisPrimary care providersPrEP demonstration projectRisk network membersNon-Hispanic whitesCisgender womenOutreach modelRespondent-driven samplingPrEP awarenessCommunity outreach modelEnrolled participantsMean ageClinical criteriaIndex participantsCare continuumHIV preventionSocial comorbiditiesCare providersKey populationsPrEPSubstance useMedical insuranceWomenPreferences for Long-Acting and Alternative Modalities for PrEP among Military Men Who Have Sex with Men: Segmentation Results of an Adaptive Choice-Based Conjoint Analysis Study
Gutierrez JI, Vlahov D, Dubov A, Altice FL. Preferences for Long-Acting and Alternative Modalities for PrEP among Military Men Who Have Sex with Men: Segmentation Results of an Adaptive Choice-Based Conjoint Analysis Study. Journal Of Urban Health 2022, 99: 277-292. PMID: 35318573, PMCID: PMC9033922, DOI: 10.1007/s11524-022-00615-9.Peer-Reviewed Original ResearchBarriers and Facilitators to Implementing Project ECHO in Malaysia During the COVID-19 Pandemic
Walters SM, Li WP, Saifi R, Azwa I, Omar S, Collier ZK, Hassan A, Haddad MS, Altice FL, Kamarulzaman A, Earnshaw VA. Barriers and Facilitators to Implementing Project ECHO in Malaysia During the COVID-19 Pandemic. Journal Of The International Association Of Providers Of AIDS Care (JIAPAC) 2022, 21: 23259582221128512. PMID: 36177542, PMCID: PMC9528038, DOI: 10.1177/23259582221128512.Peer-Reviewed Original Research
2021
Methadone within prison and linkage to and retention in treatment upon community release for people with opioid use disorder in Kyrgyzstan: Evaluation of a national program
Bachireddy C, Shrestha R, Bromberg DJ, Azbel L, Kurmanalieva A, Wegman M, Shumskaya N, Rozanova J, Meyer JP, Altice FL. Methadone within prison and linkage to and retention in treatment upon community release for people with opioid use disorder in Kyrgyzstan: Evaluation of a national program. International Journal Of Drug Policy 2021, 101: 103558. PMID: 34915426, PMCID: PMC9998103, DOI: 10.1016/j.drugpo.2021.103558.Peer-Reviewed Original ResearchConceptsHIV statusMean treatment durationOpioid use disorderPositive HIV statusDuration of treatmentMethadone doseHIV incidenceMethadone servicesMethadone treatmentIndependent correlatesHIV preventionUse disordersTreatment durationMethadoneNational programTreatmentHIVAdministrative dataCommunity releaseMonthsKyrgyz prisonsFirst evaluationIncarcerated peopleDurationReleasePreference for and Efficacy of a PrEP Decision Aid for Women with Substance Use Disorders
Meyer J, Price C, Tracey D, Sharpless L, Song Y, Madden L, Elwyn G, Altice F. Preference for and Efficacy of a PrEP Decision Aid for Women with Substance Use Disorders. Patient Preference And Adherence 2021, 15: 1913-1927. PMID: 34511887, PMCID: PMC8420782, DOI: 10.2147/ppa.s315543.Peer-Reviewed Original ResearchSubstance use disordersPersonal HIV riskHIV preventionAddiction treatment servicesHIV riskUse disordersTreatment servicesPatient-centered decision aidAwareness of PrEPHIV prevention cascadeInitiation of PrEPPre-exposure prophylaxisOpioid use disorderStandard of careDecision aidAlcohol use severityHalf of participantsAddiction treatment programsDA participantsPrevention cascadePrimary outcomeIndependent correlatesHigh riskDecisional preferencesHigher alcohol use severityDecisional considerations for methadone uptake in Kyrgyz prisons: The importance of understanding context and providing accurate information
Liberman AR, Bromberg DJ, Azbel L, Rozanova J, Madden L, Meyer JP, Altice FL. Decisional considerations for methadone uptake in Kyrgyz prisons: The importance of understanding context and providing accurate information. International Journal Of Drug Policy 2021, 94: 103209. PMID: 33838398, PMCID: PMC8373625, DOI: 10.1016/j.drugpo.2021.103209.Peer-Reviewed Original ResearchConceptsKyrgyz prisonsInformal governance systemSecondary thematic analysisMethadone uptakePrison governanceGovernance systemPrison economyPrison administrationQualitative interviewsInterrelated themesSocial risksPrison contextEastern EuropePrisonCentral AsiaKyrgyz RepublicUnderstanding contextThematic analysisDecisional considerationsContent analysisMethadone treatmentRespondents' perceptionsHIV preventionMethadone utilizationInterviewsAssessing mobile technology use and mHealth acceptance among HIV-positive men who have sex with men and transgender women in Malaysia
Krishnan A, Weikum D, Cravero C, Kamarulzaman A, Altice FL. Assessing mobile technology use and mHealth acceptance among HIV-positive men who have sex with men and transgender women in Malaysia. PLOS ONE 2021, 16: e0248705. PMID: 33755693, PMCID: PMC7987189, DOI: 10.1371/journal.pone.0248705.Peer-Reviewed Original ResearchConceptsSuboptimal ART adherenceTransgender womenAntiretroviral therapyART adherenceHIV-positive MSMHIV-positive populationInjection drug useHIV-positive menAcceptability of mHealthRisky sexual behaviorHIV preventionTreatment strategiesUnsafe sexDrug useMHealth acceptanceExcellent accessMHealth platformSexual behaviorMenMobile healthSocietal stigmaSexMSMMHealth researchWomenThe opioid crisis and HIV in the USA: deadly synergies
Hodder SL, Feinberg J, Strathdee SA, Shoptaw S, Altice FL, Ortenzio L, Beyrer C. The opioid crisis and HIV in the USA: deadly synergies. The Lancet 2021, 397: 1139-1150. PMID: 33617769, DOI: 10.1016/s0140-6736(21)00391-3.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAnalgesics, OpioidBlack or African AmericanCase-Control StudiesDisease OutbreaksEvidence-Based MedicineFemaleFentanylHealth Services AccessibilityHispanic or LatinoHIV InfectionsHumansMaleNeedle SharingOpiate OverdoseOpioid EpidemicOpioid-Related DisordersSocial StigmaUnited StatesWhite PeopleYoung AdultConceptsNew HIV diagnosesHIV diagnosisOpioid epidemicHIV preventionMultiple evidence-based interventionsGreat public health problemRecent HIV outbreaksOpioid overdose death ratesOpioid use disorderLarge central metropolitan areasPublic health problemOverdose death ratesComprehensive health careEvidence-based interventionsDeadly synergyHIV acquisitionSynthetic opioid fentanylSyringe sharingHIV outbreakUse disordersOpioid fentanylTreatment servicesHealth problemsOpioid crisisDeath rate
2020
Awareness about and willingness to use long-acting injectable pre-exposure prophylaxis (LAI-PrEP) among people who use drugs
Shrestha R, DiDomizio EE, Kim RS, Altice FL, Wickersham JA, Copenhaver MM. Awareness about and willingness to use long-acting injectable pre-exposure prophylaxis (LAI-PrEP) among people who use drugs. Journal Of Substance Use And Addiction Treatment 2020, 117: 108058. PMID: 32811633, PMCID: PMC7438607, DOI: 10.1016/j.jsat.2020.108058.Peer-Reviewed Original ResearchConceptsPre-exposure prophylaxisInjectable pre-exposure prophylaxisLAI-PrEPOral pre-exposure prophylaxisLong-term side effectsSelf-reported HIV risk behaviorsBangkok Tenofovir StudyEvidence-based HIVHigh-risk PWUDImportant key populationHIV-negative peopleOpioid use disorderHIV risk behaviorsHIV prevention effortsAddiction treatment programsDaily PrEPOral PrEPAdherence challengesIndependent correlatesFemale sexClinical trialsHIV preventionIndependent factorsSide effectsUse disordersFeasibility and Acceptability of an mHealth-Based Approach as an HIV Prevention Strategy Among People Who Use Drugs on Pre-Exposure Prophylaxis
Shrestha R, Altice FL, DiDomizio E, Sibilio B, Ranjit YS, Copenhaver MM. Feasibility and Acceptability of an mHealth-Based Approach as an HIV Prevention Strategy Among People Who Use Drugs on Pre-Exposure Prophylaxis. Patient Preference And Adherence 2020, 14: 107-118. PMID: 32021122, PMCID: PMC6971384, DOI: 10.2147/ppa.s236794.Peer-Reviewed Original ResearchPre-exposure prophylaxisHIV risk reductionHIV preventionText messaging servicePrimary HIV preventionHIV prevention strategiesOpioid-dependent peopleReminder text messagesWeekly text messagesPost-intervention assessmentRisk reductionForty HIVPrEP adherenceText messagesSMS remindersRisk groupsText remindersPrevention strategiesUnderserved populationsMHealth technologiesAcceptability studyHealth carePreventionProphylaxisPreliminary evidence
2019
Online HIV information seeking and pre-exposure prophylaxis awareness among people who use drugs
Ranjit YS, Shrestha R, Copenhaver M, Altice FL. Online HIV information seeking and pre-exposure prophylaxis awareness among people who use drugs. Journal Of Substance Use And Addiction Treatment 2019, 111: 16-22. PMID: 32087834, PMCID: PMC7039922, DOI: 10.1016/j.jsat.2019.12.010.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusHIV informationMethadone treatmentPre-exposure prophylaxis (PrEP) awarenessPre-exposure prophylaxisNew HIV diagnosesHIV-negative PWUDBehavior change continuumCross-sectional surveyMethods of preventionAddiction treatment programsHIV diagnosisImmunodeficiency virusInjection drugsHIV preventionHigh riskGeneral populationSex partnersOverall healthTreatment programPrEPDrugsPWUDChange continuumRiskEffect of expanding opioid agonist therapies on the HIV epidemic and mortality in Ukraine: a modelling study
Tan J, Altice FL, Madden LM, Zelenev A. Effect of expanding opioid agonist therapies on the HIV epidemic and mortality in Ukraine: a modelling study. The Lancet HIV 2019, 7: e121-e128. PMID: 31879250, PMCID: PMC7289179, DOI: 10.1016/s2352-3018(19)30373-x.Peer-Reviewed Original ResearchConceptsOpioid agonist therapyNew HIV infectionsHigh HIV burdenHIV infectionMinistry of HealthOAT coverageAgonist therapyHIV burdenHIV incidenceBuprenorphine maintenance therapyPublic Health CenterMaintenance therapyHIV outcomesHIV prevalenceHIV transmissionMedication procurementHIV epidemicHealth centersHIV preventionTreatment goalsPWIDOAT expansionDisease controlSexual riskInfection