2016
CYP2A6 metabolism in the development of smoking behaviors in young adults
Olfson E, Bloom J, Bertelsen S, Budde JP, Breslau N, Brooks A, Culverhouse R, Chan G, Chen L, Chorlian D, Dick DM, Edenberg HJ, Hartz S, Hatsukami D, Hesselbrock VM, Johnson EO, Kramer JR, Kuperman S, Meyers JL, Nurnberger J, Porjesz B, Saccone NL, Schuckit MA, Stitzel J, Tischfield JA, Rice JP, Goate A, Bierut LJ. CYP2A6 metabolism in the development of smoking behaviors in young adults. Addiction Biology 2016, 23: 437-447. PMID: 28032407, PMCID: PMC5491369, DOI: 10.1111/adb.12477.Peer-Reviewed Original ResearchMeSH KeywordsAdultCigarette SmokingCytochrome P-450 CYP2A6FemaleHumansMaleOdds RatioPolymorphism, Single NucleotideTobacco Use DisorderWhite PeopleYoung AdultConceptsNicotine dependenceSlow metabolizersDaily smokersYoung adultsSmoking behaviorCYP2A6 variationNicotine metabolismRole of CYP2A6Adult daily smokersDevelopment of dependenceCollaborative Genetics StudyGenetics of AlcoholismSmoking milestonesCytochrome P450 2A6Young adult daily smokersNormal metabolizersCollaborative studyDaily smokingFirst cigaretteSecondary analysisCYP2A6 variantsMetabolizersYoung adulthoodP450 2A6Conflicting results
2015
When Does Choice of Accuracy Measure Alter Imputation Accuracy Assessments?
Ramnarine S, Zhang J, Chen LS, Culverhouse R, Duan W, Hancock DB, Hartz SM, Johnson EO, Olfson E, Schwantes-An TH, Saccone NL. When Does Choice of Accuracy Measure Alter Imputation Accuracy Assessments? PLOS ONE 2015, 10: e0137601. PMID: 26458263, PMCID: PMC4601794, DOI: 10.1371/journal.pone.0137601.Peer-Reviewed Original ResearchRare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans
Olfson E, Saccone NL, Johnson EO, Chen LS, Culverhouse R, Doheny K, Foltz SM, Fox L, Gogarten SM, Hartz S, Hetrick K, Laurie CC, Marosy B, Amin N, Arnett D, Barr RG, Bartz TM, Bertelsen S, Borecki IB, Brown MR, Chasman DI, van Duijn CM, Feitosa MF, Fox ER, Franceschini N, Franco OH, Grove ML, Guo X, Hofman A, Kardia SL, Morrison AC, Musani SK, Psaty BM, Rao DC, Reiner AP, Rice K, Ridker PM, Rose LM, Schick UM, Schwander K, Uitterlinden AG, Vojinovic D, Wang JC, Ware EB, Wilson G, Yao J, Zhao W, Breslau N, Hatsukami D, Stitzel JA, Rice J, Goate A, Bierut LJ. Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans. Molecular Psychiatry 2015, 21: 601-607. PMID: 26239294, PMCID: PMC4740321, DOI: 10.1038/mp.2015.105.Peer-Reviewed Original Research