Featured Publications
Habitual sleep duration and its relationship with cardiovascular health, healthcare costs, and resource utilization in a working population
Aneni E, Osondu C, Joseph J, Saeed G, Valero-Elizondo J, Veledar E, Nasir K. Habitual sleep duration and its relationship with cardiovascular health, healthcare costs, and resource utilization in a working population. Sleep Health 2022, 9: 77-85. PMID: 36371382, PMCID: PMC9991949, DOI: 10.1016/j.sleh.2022.10.001.Peer-Reviewed Original ResearchMeSH KeywordsAdultCardiovascular DiseasesFloridaHealth Care CostsHumansRisk AssessmentSleep DurationConceptsCardiovascular healthHabitual sleep durationSleep durationHealthcare expendituresHealthcare costsOptimal cardiovascular healthIdeal cardiovascular healthBaptist Health South FloridaHealthcare resource utilizationBody mass indexBetter cardiovascular healthMedical claims dataHours of sleepLower healthcare expendituresCVH metricsMore hoursBlood pressureMass indexMean ageEmergency roomCardiovascular diseaseHigher oddsHispanic ethnicityPhysical activityClaims dataThe relationship of erectile dysfunction and subclinical cardiovascular disease: A systematic review and meta-analysis
Osondu CU, Vo B, Oni ET, Blaha MJ, Veledar E, Feldman T, Agatston AS, Nasir K, Aneni EC. The relationship of erectile dysfunction and subclinical cardiovascular disease: A systematic review and meta-analysis. Vascular Medicine 2017, 23: 9-20. PMID: 29243995, DOI: 10.1177/1358863x17725809.Peer-Reviewed Original ResearchMeSH KeywordsCardiovascular DiseasesCarotid Intima-Media ThicknessCoronary Artery DiseaseErectile DysfunctionHumansMalePulse Wave AnalysisRisk FactorsConceptsCarotid intima-media thicknessAssociation of EDFlow-mediated dilationSubclinical cardiovascular diseaseCoronary artery calcificationErectile dysfunctionCardiovascular diseaseHigher carotid intima-media thicknessAnkle-brachial indexToe-brachial indexCVD risk assessmentIntima-media thicknessPulse wave velocityArtery calcificationEndothelial dysfunctionCVD mortalityMean ageVascular functionStudy qualityStudy populationAssessment QuestionnaireSystematic reviewDysfunctionPercentage point reductionMultiple databasesEstimates of Mortality Benefit From Ideal Cardiovascular Health Metrics: A Dose Response Meta‐Analysis
Aneni EC, Crippa A, Osondu CU, Valero‐Elizondo J, Younus A, Nasir K, Veledar E. Estimates of Mortality Benefit From Ideal Cardiovascular Health Metrics: A Dose Response Meta‐Analysis. Journal Of The American Heart Association 2017, 6: e006904. PMID: 29269350, PMCID: PMC5779012, DOI: 10.1161/jaha.117.006904.Peer-Reviewed Original ResearchMeSH KeywordsCardiovascular DiseasesGlobal HealthHealth StatusHumansLife StyleQuality Indicators, Health CareRisk AssessmentRisk FactorsSurvival RateConceptsIdeal cardiovascular healthIdeal CVH metricsPooled hazard ratioCVH metricsCardiovascular healthMortality benefitHazard ratioCardiovascular disease-related mortalityDose–response meta analysisStrong public health messageIdeal cardiovascular health metricsSubstantial mortality benefitCardiovascular health metricsCardiovascular disease mortalityLinear dose-response relationshipDisease-related mortalityPublic health messagesHazard ratio estimatesDose-response relationshipUnit increaseWeb of ScienceCause mortalityInternet literature searchDisease mortalityCardiovascular diseaseA Systematic Review of Internet-Based Worksite Wellness Approaches for Cardiovascular Disease Risk Management: Outcomes, Challenges & Opportunities
Aneni EC, Roberson LL, Maziak W, Agatston AS, Feldman T, Rouseff M, Tran TH, Blumenthal RS, Blaha MJ, Blankstein R, Al-Mallah MH, Budoff MJ, Nasir K. A Systematic Review of Internet-Based Worksite Wellness Approaches for Cardiovascular Disease Risk Management: Outcomes, Challenges & Opportunities. PLOS ONE 2014, 9: e83594. PMID: 24421894, PMCID: PMC3885454, DOI: 10.1371/journal.pone.0083594.Peer-Reviewed Original ResearchMeSH KeywordsCardiovascular DiseasesHealth PromotionHumansInternetPubMedRisk ManagementTreatment OutcomeWorkplaceConceptsInternet-based programCardiovascular wellnessSystematic reviewCardiovascular disease risk managementCardiovascular health outcomesInclusion/exclusion criteriaPhysical activity outcomesSpecific disease entityWeb of ScienceCV healthRandomized trialsCochrane LibraryBlood glucoseDisease entityDisease risk managementPhysical activityExclusion criteriaRisk populationsHealth outcomesWellness interventionsPrevention programsActivity outcomesIntervention typeWellness approachBlue-collar workers
2019
Gaps in provider lifestyle counseling and its adherence among obese adults with prediabetes and diabetes in the United States
Valero-Elizondo J, Aneni EC, Osondu CU, Grandhi GR, Virani SS, Nasir K. Gaps in provider lifestyle counseling and its adherence among obese adults with prediabetes and diabetes in the United States. Preventive Medicine 2019, 129: 105815. PMID: 31454663, DOI: 10.1016/j.ypmed.2019.105815.Peer-Reviewed Original ResearchConceptsLifestyle counselingObese adultsHealthcare providersManagement of obesityPrevalence of diabetesWeight loss programUS adult populationLevels of obesityLifestyle modificationDiabetes statusObese patientsSevere obesityLoss programMild obesityCardiovascular diseasePhysical activityObesity epidemicObesityDiabetesMetabolic diseasesAdult populationHealthy lifestyleCounselingPatientsAdults
2016
Chronic Toxic Metal Exposure and Cardiovascular Disease: Mechanisms of Risk and Emerging Role of Chelation Therapy
Aneni EC, Escolar E, Lamas GA. Chronic Toxic Metal Exposure and Cardiovascular Disease: Mechanisms of Risk and Emerging Role of Chelation Therapy. Current Atherosclerosis Reports 2016, 18: 81. PMID: 27822681, DOI: 10.1007/s11883-016-0631-0.Peer-Reviewed Original ResearchMeSH KeywordsCardiovascular DiseasesChelating AgentsChelation TherapyHeavy Metal PoisoningHumansPoisoningRiskSecondary PreventionConceptsCardiovascular diseaseSecondary preventionToxic metal exposureChelation therapyCardiovascular disease-related morbidityDisease-related morbidityAtherosclerotic cardiovascular diseaseMulticenter trialEpidemiologic evidenceMetal exposureChronic exposurePositive findingsMechanisms of riskDiseaseEmerging RoleRecent evidenceTherapyExposurePreventionMetal chelation therapyMorbidityMortalityFindingsTrialsA Systematic Review of the Prevalence and Outcomes of Ideal Cardiovascular Health in US and Non-US Populations
Younus A, Aneni EC, Spatz ES, Osondu CU, Roberson L, Ogunmoroti O, Malik R, Ali SS, Aziz M, Feldman T, Virani SS, Maziak W, Agatston AS, Veledar E, Nasir K. A Systematic Review of the Prevalence and Outcomes of Ideal Cardiovascular Health in US and Non-US Populations. Mayo Clinic Proceedings 2016, 91: 649-670. PMID: 27040086, DOI: 10.1016/j.mayocp.2016.01.019.Peer-Reviewed Original ResearchConceptsIdeal CVH metricsNon-CVD outcomesIdeal cardiovascular health metricsCVH metricsIdeal cardiovascular healthCardiovascular healthLow prevalenceAmerican Heart Association ideal cardiovascular health (CVH) metricsSystematic reviewMore ideal CVH metricsIncident cardiovascular eventsCardiovascular health metricsPopulation-based studyNon-US populationsCochrane RegisterCardiovascular eventsControlled TrialsUS cohortInverse associationCardiovascular diseaseCINAHL databasesMortality riskMortality studyCognitive impairmentUS population
2015
Prevalence of Ideal Cardiovascular Health Among Adults in the United States
Younus A, Aneni EC, Spatz ES, Osondu CU, Shaharyar S, Roberson L, Ali SS, Ogunmoroti O, Ahmad R, Post J, Feldman T, Maziak W, Agatston AS, Veledar E, Nasir K. Prevalence of Ideal Cardiovascular Health Among Adults in the United States. Journal Of The American College Of Cardiology 2015, 66: 1633-1634. PMID: 26429090, DOI: 10.1016/j.jacc.2015.06.1348.Peer-Reviewed Original ResearchAdultAgedCardiovascular DiseasesFemaleHealth BehaviorHealth StatusHumansMaleMiddle AgedPrevalenceUnited States
2014
Beyond BMI: The “Metabolically healthy obese” phenotype & its association with clinical/subclinical cardiovascular disease and all-cause mortality -- a systematic review
Roberson LL, Aneni EC, Maziak W, Agatston A, Feldman T, Rouseff M, Tran T, Blaha MJ, Santos RD, Sposito A, Al-Mallah MH, Blankstein R, Budoff MJ, Nasir K. Beyond BMI: The “Metabolically healthy obese” phenotype & its association with clinical/subclinical cardiovascular disease and all-cause mortality -- a systematic review. BMC Public Health 2014, 14: 14. PMID: 24400816, PMCID: PMC3890499, DOI: 10.1186/1471-2458-14-14.Peer-Reviewed Original ResearchMeSH KeywordsBody Mass IndexCardiovascular DiseasesCarotid Intima-Media ThicknessCause of DeathFemaleHumansInsulin ResistanceMaleMetabolic SyndromeObesityPhenotypeRisk FactorsConceptsIncident cardiovascular diseaseCoronary artery calciumSubclinical cardiovascular diseaseCause mortalityCardiovascular diseaseCVD mortalityCommon carotid artery intima-media thicknessAdult Treatment Panel III definitionCarotid artery intima-media thicknessArtery intima-media thicknessDefinition of MHOHealthy obese populationSubclinical CVD markersTypical metabolic disordersMetabolic syndrome componentsIntima-media thicknessRisk cardiovascular diseaseWeb of ScienceCVD markersHealthy obeseMHO groupArtery calciumCVD riskSyndrome componentsMetabolic syndrome