Featured Publications
Early Adversity and Development: Parsing Heterogeneity and Identifying Pathways of Risk and Resilience
Gee DG. Early Adversity and Development: Parsing Heterogeneity and Identifying Pathways of Risk and Resilience. American Journal Of Psychiatry 2021, 178: 998-1013. PMID: 34734741, DOI: 10.1176/appi.ajp.2021.21090944.Peer-Reviewed Original ResearchConceptsEarly adversityProtective factorsEffects of adversityOnset of psychopathologyPathways of riskNeurodevelopmental trajectoriesMajor risk factorAdversityMental healthNeurodevelopmental pathwaysEarly environmentPsychopathologySpecific dimensionsIntervention strategiesFuture researchRisk factorsEarly risk identificationTreatment approachesImmense burdenConceptual modelDevelopmental timingResilienceOngoing refinementRiskFactorsAssociations among negative life events, changes in cortico-limbic connectivity, and psychopathology in the ABCD Study
Brieant AE, Sisk LM, Gee DG. Associations among negative life events, changes in cortico-limbic connectivity, and psychopathology in the ABCD Study. Developmental Cognitive Neuroscience 2021, 52: 101022. PMID: 34710799, PMCID: PMC8556598, DOI: 10.1016/j.dcn.2021.101022.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentHumansMagnetic Resonance ImagingMental DisordersNeurobiologyParentsPsychopathologyRisk FactorsConceptsResting-state functional connectivityNegative life eventsLife eventsInternalizing symptomsAdversity exposureCortico-limbic connectivityParental acceptanceAdolescent Brain Cognitive Development (ABCD) studyLongitudinal structural equation modelLower internalizing symptomsCognitive Development StudyContext of adversityIndirect effectsSample of youthStressful childhood experiencesCortico-limbic networkStructural equation modelLater psychopathologyNeurobiological maturationInternalizing problemsABCD studyFunctional connectivityChildhood experiencesPotential protective effectPsychopathology
2021
Stress and adolescence: vulnerability and opportunity during a sensitive window of development
Sisk LM, Gee DG. Stress and adolescence: vulnerability and opportunity during a sensitive window of development. Current Opinion In Psychology 2021, 44: 286-292. PMID: 34818623, PMCID: PMC9007828, DOI: 10.1016/j.copsyc.2021.10.005.Peer-Reviewed Original ResearchDecomposing complex links between the childhood environment and brain structure in school-aged youth
Hong SJ, Sisk LM, Caballero C, Mekhanik A, Roy AK, Milham MP, Gee DG. Decomposing complex links between the childhood environment and brain structure in school-aged youth. Developmental Cognitive Neuroscience 2021, 48: 100919. PMID: 33556882, PMCID: PMC7868609, DOI: 10.1016/j.dcn.2021.100919.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdolescent DevelopmentBrainChildCognitionFemaleHumansMalePsychopathologySchoolsConceptsSupportive caregivingAdolescent Brain Cognitive Development (ABCD) studyOverall mental health problemsCross-modal integrationHigh family conflictCognitive Development StudyBrain structuresDistinct environmental exposuresSchool-aged youthMental health problemsSchool-aged childrenGreater cortical thicknessExternalizing symptomsFamily conflictGreater myelinationBehavioral developmentBrain morphometricsStructural neurodevelopmentChildhood experiencesProtective factorsOptimize interventionsNeighborhood safetyDifferent facetsSchool environmentSpecific experiences