2023
Segmentation-Free PVC for Cardiac SPECT Using a Densely-Connected Multi-Dimensional Dynamic Network
Xie H, Liu Z, Shi L, Greco K, Chen X, Zhou B, Feher A, Stendahl J, Boutagy N, Kyriakides T, Wang G, Sinusas A, Liu C. Segmentation-Free PVC for Cardiac SPECT Using a Densely-Connected Multi-Dimensional Dynamic Network. IEEE Transactions On Medical Imaging 2023, 42: 1325-1336. PMID: 36459599, PMCID: PMC10204821, DOI: 10.1109/tmi.2022.3226604.Peer-Reviewed Original Research
2020
Feasibility study of PET dynamic imaging of [18F]DHMT for quantification of reactive oxygen species in the myocardium of large animals
Wu J, Boutagy NE, Cai Z, Lin SF, Zheng MQ, Feher A, Stendahl JC, Kapinos M, Gallezot JD, Liu H, Mulnix T, Zhang W, Lindemann M, Teng JK, Miller EJ, Huang Y, Carson RE, Sinusas AJ, Liu C. Feasibility study of PET dynamic imaging of [18F]DHMT for quantification of reactive oxygen species in the myocardium of large animals. Journal Of Nuclear Cardiology 2020, 29: 216-225. PMID: 32415628, PMCID: PMC7666654, DOI: 10.1007/s12350-020-02184-3.Peer-Reviewed Original Research
2019
Direct List Mode Parametric Reconstruction for Dynamic Cardiac SPECT
Shi L, Lu Y, Wu J, Gallezot JD, Boutagy N, Thorn S, Sinusas AJ, Carson RE, Liu C. Direct List Mode Parametric Reconstruction for Dynamic Cardiac SPECT. IEEE Transactions On Medical Imaging 2019, 39: 119-128. PMID: 31180845, PMCID: PMC7030971, DOI: 10.1109/tmi.2019.2921969.Peer-Reviewed Original ResearchConceptsAppropriate kinetic modelConventional indirect methodImage reconstruction algorithmKinetic modelHigh noise levelsLow count levelsVivo canine studyIndirect methodImage noiseNoise levelParametric reconstructionNoiseReconstruction algorithmFrame imagePatient radiation dose reductionMethodDirect methodLower image noiseData-driven voluntary body motion detection and non-rigid event-by-event correction for static and dynamic PET
Lu Y, Gallezot JD, Naganawa M, Ren S, Fontaine K, Wu J, Onofrey JA, Toyonaga T, Boutagy N, Mulnix T, Panin VY, Casey ME, Carson RE, Liu C. Data-driven voluntary body motion detection and non-rigid event-by-event correction for static and dynamic PET. Physics In Medicine And Biology 2019, 64: 065002. PMID: 30695768, DOI: 10.1088/1361-6560/ab02c2.Peer-Reviewed Original Research
2017
Quantification of intramyocardial blood volume with 99mTc-RBC SPECT-CT imaging: A preclinical study
Mohy-Ud-Din H, Boutagy NE, Stendahl JC, Zhuang ZW, Sinusas AJ, Liu C. Quantification of intramyocardial blood volume with 99mTc-RBC SPECT-CT imaging: A preclinical study. Journal Of Nuclear Cardiology 2017, 25: 2096-2111. PMID: 28695406, PMCID: PMC5985225, DOI: 10.1007/s12350-017-0970-4.Peer-Reviewed Original ResearchFully automatic multi-atlas segmentation of CTA for partial volume correction in cardiac SPECT/CT
Liu Q, Mohy-ud-Din H, Boutagy N, Jiang M, Ren S, Stendahl J, Sinusas A, Liu C. Fully automatic multi-atlas segmentation of CTA for partial volume correction in cardiac SPECT/CT. Physics In Medicine And Biology 2017, 62: 3944-3957. PMID: 28266929, PMCID: PMC5568763, DOI: 10.1088/1361-6560/aa6520.Peer-Reviewed Original ResearchConceptsMulti-atlas segmentation methodLabel fusion methodMulti-atlas segmentationSegmentation methodConventional label fusion methodsFusion methodManual segmentationMultiple organ segmentationLabel fusion algorithmImage qualityCardiac SPECT imagesDice similarity coefficientOrgan segmentationSegmentation accuracyAutomatic segmentationCTA segmentationFusion algorithmComputed tomography angiography dataSegmentationOne-out approachCT datasetsTomography angiography dataSimilarity coefficientAngiography dataConsistent image quality
2016
Noise suppressed partial volume correction for cardiac SPECT/CT
Chan C, Liu H, Grobshtein Y, Stacy MR, Sinusas AJ, Liu C. Noise suppressed partial volume correction for cardiac SPECT/CT. Medical Physics 2016, 43: 5225-5239. PMID: 27587054, PMCID: PMC5001975, DOI: 10.1118/1.4961391.Peer-Reviewed Original Research
2015
Anatomical-based partial volume correction for low-dose dedicated cardiac SPECT/CT
Liu H, Chan C, Grobshtein Y, Ma T, Liu Y, Wang S, Stacy MR, Sinusas AJ, Liu C. Anatomical-based partial volume correction for low-dose dedicated cardiac SPECT/CT. Physics In Medicine And Biology 2015, 60: 6751-6773. PMID: 26296043, PMCID: PMC4747118, DOI: 10.1088/0031-9155/60/17/6751.Peer-Reviewed Original ResearchAnimalsBlood VolumeCardiac-Gated Single-Photon Emission Computer-Assisted TomographyDogsDose-Response Relationship, RadiationErythrocytesHeartHumansImage EnhancementImage Interpretation, Computer-AssistedModels, CardiovascularMyocardial Perfusion ImagingOrganophosphorus CompoundsOrganotechnetium CompoundsPhantoms, ImagingRadiopharmaceuticalsReproducibility of ResultsSwineTissue DistributionTomography, X-Ray Computed