2022
Regional Brain Volume Abnormalities and Long-term Cognitive Outcome in Preterm Infants
Peterson B, Vohr B, Staib L, Cannistraci C, Dolberg A, Schneider K, Katz K, Westerveld M, Sparrow S, Anderson A, Duncan C, Makuch R, Gore J, Ment L. Regional Brain Volume Abnormalities and Long-term Cognitive Outcome in Preterm Infants. 2022, 215-223. DOI: 10.4324/9780203822937-21.Peer-Reviewed Original ResearchRegional brain volumesLong-term cognitive outcomesBrain volumePreterm infantsRegional brain volume abnormalitiesMagnetic resonance imaging (MRI) scansCognitive outcomesTerm control childrenPerinatal risk factorsResonance imaging scansBrain volume abnormalitiesPreterm cohortRisk factorsImaging scansPreterm childrenHigh prevalenceVolume abnormalitiesBehavioral disturbancesControl childrenTerm controlsAbnormalitiesInfantsChildrenOutcomesCognitive measures
2021
Functional Network Development in Sagittal Craniosynostosis Treated With Whole Vault Cranioplasty
Cabrejo R, Lacadie C, Sun A, Chuang C, Yang J, Brooks E, Beckett J, Eilbott J, Gabrick K, Steinbacher D, Duncan C, DiLuna M, Alperovich M, Pelphrey K, Ventola P, Constable T, Persing JA. Functional Network Development in Sagittal Craniosynostosis Treated With Whole Vault Cranioplasty. Journal Of Craniofacial Surgery 2021, 32: 1721-1726. PMID: 33534301, DOI: 10.1097/scs.0000000000007505.Peer-Reviewed Original ResearchConceptsWhole-vault cranioplastySagittal craniosynostosisFunctional MRICase-control study designFunctional MRI scansControl study designAbnormal network connectionsFunctional network developmentNeurological changesIndividual patientsMRI scansFunctional brain networksCerebral networksFunctional connectivityVisual networkConnectivity changesPatientsStudy designSurgeryAdolescent controlsBrain networksCraniosynostosisWVC groupInfantsExecutive functionLong-Term Neurocognitive Outcomes in Sagittal Synostosis: The Impact of Reoperation.
Chuang C, Chaunzwa TL, Wu R, Singh A, Patel A, Yang JF, Hashim PW, Travieso R, Terner JS, Mayes LC, Duncan CC, Jane JA, Lin KY, Bridgett DJ, Persing JA. Long-Term Neurocognitive Outcomes in Sagittal Synostosis: The Impact of Reoperation. Journal Of Craniofacial Surgery 2021, 32: 58-61. PMID: 33394632, DOI: 10.1097/scs.0000000000006909.Peer-Reviewed Original ResearchConceptsEarly surgery patientsImpact of reoperationSurgery patientsNonsyndromic sagittal craniosynostosisNeurocognitive outcomesWhole-vault cranioplastyReoperation rateSagittal craniosynostosisVisuomotor integrationComprehensive neurocognitive testingLate surgery patientsWorse neurocognitive outcomesTerm Neurocognitive OutcomesStandardized neuropsychological testingLife surgeryUnderwent reoperationEarly surgeryLate surgerySchool-aged childrenReoperationOutcome measuresNeuropsychological testingPatientsNeurocognitive testingNeurocognitive function
2020
Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus
Jin SC, Dong W, Kundishora AJ, Panchagnula S, Moreno-De-Luca A, Furey CG, Allocco AA, Walker RL, Nelson-Williams C, Smith H, Dunbar A, Conine S, Lu Q, Zeng X, Sierant MC, Knight JR, Sullivan W, Duy PQ, DeSpenza T, Reeves BC, Karimy JK, Marlier A, Castaldi C, Tikhonova IR, Li B, Peña HP, Broach JR, Kabachelor EM, Ssenyonga P, Hehnly C, Ge L, Keren B, Timberlake AT, Goto J, Mangano FT, Johnston JM, Butler WE, Warf BC, Smith ER, Schiff SJ, Limbrick DD, Heuer G, Jackson EM, Iskandar BJ, Mane S, Haider S, Guclu B, Bayri Y, Sahin Y, Duncan CC, Apuzzo MLJ, DiLuna ML, Hoffman EJ, Sestan N, Ment LR, Alper SL, Bilguvar K, Geschwind DH, Günel M, Lifton RP, Kahle KT. Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus. Nature Medicine 2020, 26: 1754-1765. PMID: 33077954, PMCID: PMC7871900, DOI: 10.1038/s41591-020-1090-2.Peer-Reviewed Original ResearchConceptsCongenital hydrocephalusPoor neurodevelopmental outcomesPost-surgical patientsCerebrospinal fluid accumulationNeural stem cell biologyGenetic disruptionWhole-exome sequencingPrimary pathomechanismEarly brain developmentNeurodevelopmental outcomesHigh morbidityCSF diversionMutation burdenFluid accumulationBrain ventriclesCH casesBrain developmentDe novo mutationsPatientsExome sequencingCSF dynamicsDisease mechanismsHydrocephalusNovo mutationsCell types
2019
S7A-19 SESSION 7A: SAGITTAL SYNOSTOSIS LONG-TERM NEUROCOGNITIVE OUTCOMES IN SAGITTAL SYNOSTOSIS: THE IMPACT OF REOPERATION
Chuang C, Chaunzwa T, Wu R, Singh A, Patel A, Yang J, Hashim P, Travieso R, Terner J, Mayes L, Duncan C, Jane J, Jane J, Lin K, Bridgett D, Persing J. S7A-19 SESSION 7A: SAGITTAL SYNOSTOSIS LONG-TERM NEUROCOGNITIVE OUTCOMES IN SAGITTAL SYNOSTOSIS: THE IMPACT OF REOPERATION. Plastic & Reconstructive Surgery Global Open 2019, 7: 77-77. DOI: 10.1097/01.gox.0000583200.60930.bb.Peer-Reviewed Original Research
2017
102 Exome Sequencing Identifies Novel Molecular Determinants of Human Congenital Hydrocephalus
Furey C, Choi J, Duran D, Timberlake A, Zeng X, Nelson-Williams C, Khanna A, Iskandar B, Butler W, Heuer G, Bayri Y, Sahin Y, Limbrick D, Warf B, Duncan C, DiLuna M, Gunel M, Lifton R, Kahle K. 102 Exome Sequencing Identifies Novel Molecular Determinants of Human Congenital Hydrocephalus. Neurosurgery 2017, 64: 220. DOI: 10.1093/neuros/nyx417.102.Peer-Reviewed Original Research
2015
Neruocognitive Effects of Metopic Synostosis Based on Severity of Deformity
Yang J, Brooks E, Hashim P, Travieso R, Terner J, Reuman H, Persing S, Zellner E, Martinez-Sawh R, Levy E, Law K, Mayes L, Duncan C, Steinbacher D, Persing J, McPartland J. Neruocognitive Effects of Metopic Synostosis Based on Severity of Deformity. Plastic & Reconstructive Surgery 2015, 136: 42-43. DOI: 10.1097/01.prs.0000472328.53040.33.Peer-Reviewed Original Research
2009
CHAPTER 33 Non-syndromic Craniosynostosis
Persing J, Knoll B, Duncan C. CHAPTER 33 Non-syndromic Craniosynostosis. 2009, 389-404. DOI: 10.1016/b978-1-4160-4081-1.50038-2.Peer-Reviewed Original Research
2005
Retinal Hemorrhages in Accidental and Nonaccidental Injury: In Reply
Bechtel K, Stoessel K, Leventhal J, Duncan C. Retinal Hemorrhages in Accidental and Nonaccidental Injury: In Reply. Pediatrics 2005, 115: 192-192. DOI: 10.1542/peds.2004-2150.Peer-Reviewed Original Research
2001
Neonatal auditory activation detected by functional magnetic resonance imaging
Anderson A, Marois R, Colson E, Peterson B, Duncan C, Ehrenkranz R, Schneider K, Gore J, Ment L. Neonatal auditory activation detected by functional magnetic resonance imaging. Magnetic Resonance Imaging 2001, 19: 1-5. PMID: 11295339, DOI: 10.1016/s0730-725x(00)00231-9.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingAuditory stimulationSuperior temporal regionsSuperior temporal gyrusAuditory cortical activationMagnetic resonance imagingFunctional brain imagingBlood oxygen level-dependent (BOLD) signalLevel-dependent signalBOLD signal responseAuditory stimuliBrain activationFMRI studyAuditory activationTemporal gyrusResonance imagingBOLD responseCortical activationHuman infantsTemporal regionsAdult control subjectsBrain imagingHealthy neonatesPure tonesControl subjects
2000
Regional Brain Volume Abnormalities and Long-term Cognitive Outcome in Preterm Infants
Peterson B, Vohr B, Staib L, Cannistraci C, Dolberg A, Schneider K, Katz K, Westerveld M, Sparrow S, Anderson A, Duncan C, Makuch R, Gore J, Ment L. Regional Brain Volume Abnormalities and Long-term Cognitive Outcome in Preterm Infants. JAMA 2000, 284: 1939-1947. PMID: 11035890, DOI: 10.1001/jama.284.15.1939.Peer-Reviewed Original ResearchConceptsRegional brain volumesLong-term cognitive outcomesPreterm childrenPreterm infantsBrain volumeBasal gangliaCorpus callosumCognitive outcomesRegional brain volume abnormalitiesTerm control childrenCase-control studyBrain volume abnormalitiesPoor cognitive outcomesRegional cortical volumesStructural magnetic resonanceMidtemporal cortexPreterm birthPremature birthTemporal hornPerinatal variablesSubgenual cortexUniversity Medical SchoolCortical volumeHigh prevalenceLongitudinal followSpontaneously Infected Cephalohematoma: Case Report and Review of the Literature
Goodwin M, Persing J, Duncan C, Shin J. Spontaneously Infected Cephalohematoma: Case Report and Review of the Literature. Journal Of Craniofacial Surgery 2000, 11: 371-375. PMID: 11314386, DOI: 10.1097/00001665-200011040-00017.Peer-Reviewed Original ResearchOutcome of Children in the Indomethacin Intraventricular Hemorrhage Prevention Trial
Ment L, Vohr B, Allan W, Westerveld M, Sparrow S, Schneider K, Katz K, Duncan C, Makuch R. Outcome of Children in the Indomethacin Intraventricular Hemorrhage Prevention Trial. Pediatrics 2000, 105: 485-491. PMID: 10699097, DOI: 10.1542/peds.105.3.485.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Inflammatory Agents, Non-SteroidalBrain Damage, ChronicCerebral HemorrhageCerebral VentriclesChild, PreschoolDose-Response Relationship, DrugFemaleFollow-Up StudiesHumansIndomethacinInfantInfant, NewbornInfant, Premature, DiseasesMaleNeurologic ExaminationNeuropsychological TestsPregnancyConceptsLow-dose indomethacinIntraventricular hemorrhagePlacebo childrenIndomethacin therapyPreterm infantsEarly administrationNeurologic examinationPrevention trialsLow birth weight preterm infantsStudy childrenBirth weight preterm infantsSeverity of IVHLow birth weight survivorsMean gestational ageWeight preterm infantsAdverse neurodevelopmental outcomesOutcome of childrenStandard neurologic examinationYears of ageNeurodevelopmental handicapPreterm neonatesNeurodevelopmental examinationNeurodevelopmental outcomesCerebral palsyGestational age
1996
Three cases of symptom change in Tourette's syndrome and obsessive-compulsive disorder associated with paediatric cerebral malignancies.
Peterson B, Bronen R, Duncan C. Three cases of symptom change in Tourette's syndrome and obsessive-compulsive disorder associated with paediatric cerebral malignancies. Journal Of Neurology Neurosurgery & Psychiatry 1996, 61: 497. PMID: 8937345, PMCID: PMC1074048, DOI: 10.1136/jnnp.61.5.497.Peer-Reviewed Case Reports and Technical NotesConceptsGilles de la Tourette's syndromeObsessive-compulsive disorderCerebral malignanciesTourette syndromeTumor progressionNeurobiology of OCDLa Tourette's syndromeImportant neural substrateChart reviewNeuropsychiatric symptomsTic symptomsTumor locationSpecialty clinicCorpus callosumRadiographic documentationSymptom generationLimbic systemCaudate nucleusIntracranial lesionsSymptom changeBrain regionsSymptom severitySyndromeVentral striatumMalignancyNeurodevelopmental outcome at 36 months' corrected age of preterm infants in the Multicenter Indomethacin Intraventricular Hemorrhage Prevention Trial.
Ment L, Vohr B, Oh W, Scott D, Allan W, Westerveld M, Duncan C, Ehrenkranz R, Katz K, Schneider K, Makuch R. Neurodevelopmental outcome at 36 months' corrected age of preterm infants in the Multicenter Indomethacin Intraventricular Hemorrhage Prevention Trial. Pediatrics 1996, 98: 714-8. PMID: 8885951, DOI: 10.1542/peds.98.4.714.Peer-Reviewed Original ResearchMeSH KeywordsCerebral HemorrhageChi-Square DistributionChild DevelopmentChild, PreschoolCyclooxygenase InhibitorsHumansIndomethacinInfantInfant, NewbornInfant, PrematureInfant, Premature, DiseasesInfant, Very Low Birth WeightIntelligence TestsNeurologic ExaminationUltrasonography, Doppler, TranscranialConceptsLow-dose indomethacinMonths' corrected ageIntraventricular hemorrhageCorrected ageNeurodevelopmental followLong-term neurodevelopmental followLow birth weight infantsLow birth weight neonatesBirth weight infantsMean gestational ageBirth weight neonatesStandard neurologic examinationAdverse cognitive outcomesIncidence of deafnessDose indomethacinWeight infantsPreterm infantsProspective trialWeight neonatesCranial ultrasoundEarly administrationNeurodevelopmental outcomesNeurologic examinationCerebral palsyGestational age
1995
Antenatal steroids, delivery mode, and intraventricular hemorrhage in preterm infants
Ment L, Oh W, Ehrenkranz R, Philip A, Duncan C, Makuch R. Antenatal steroids, delivery mode, and intraventricular hemorrhage in preterm infants. American Journal Of Obstetrics And Gynecology 1995, 172: 795-800. PMID: 7892866, DOI: 10.1016/0002-9378(95)90001-2.Peer-Reviewed Original ResearchConceptsEarly intraventricular hemorrhageAntenatal steroidsIntraventricular hemorrhageCesarean sectionPreterm infantsAntenatal steroid treatmentCesarean section deliveryHours of lifeMore vaginal deliveriesDelivery modePostnatal indomethacinSection deliveryWeight infantsSteroid treatmentVaginal deliveryHemorrhageInfantsSteroidsIndependent roleHoursDeliveryMulticenterIndomethacinTrialsEchoencephalography
1994
Low-dose indomethacin therapy and extension of intraventricular hemorrhage: A multicenter randomized trial
Ment L, Oh W, Ehrenkranz R, Phillip A, Vohr B, Allan W, Makuch R, Taylor K, Schneider K, Katz K, Scott D, Duncan C. Low-dose indomethacin therapy and extension of intraventricular hemorrhage: A multicenter randomized trial. The Journal Of Pediatrics 1994, 124: 951-955. PMID: 8201485, DOI: 10.1016/s0022-3476(05)83191-9.Peer-Reviewed Original ResearchConceptsLow-grade intraventricular hemorrhageIntraventricular hemorrhageAdverse eventsBirth weightLow birth weight infantsDistribution of hemorrhageGrade intraventricular hemorrhageBirth weight infantsPlacebo-controlled trialPercentage of infantsPatent ductus arteriosusGm birth weightHours of ageIndomethacin therapyWeight infantsApgar scoreParenchymal involvementSaline placeboDuctus arteriosusGestational ageIntracranial hemorrhagePostnatal hoursCascade of eventsPatent ductusCranial sonogramsLow-dose indomethacin and prevention of intraventricular hemorrhage: a multicenter randomized trial.
Ment L, Ehrenkranz R, Duncan C, Scott D, Taylor K, Katz K, Schneider K, Makuch R, Oh W, Vohr B, Philip A, Allan W. Low-dose indomethacin and prevention of intraventricular hemorrhage: a multicenter randomized trial. Pediatrics 1994, 93: 543-50. PMID: 8134206, DOI: 10.1542/peds.93.4.543.Peer-Reviewed Original ResearchConceptsLow birth weight neonatesSeverity of IVHBirth weight neonatesIntraventricular hemorrhageWeight neonatesDose indomethacinBirth weightGrade 4 intraventricular hemorrhageSerial cranial ultrasound examinationsSignificant adverse drug eventsPercent of neonatesPlacebo-controlled trialPatent ductus arteriosusCranial ultrasound examinationMajor risk factorAdverse drug eventsHours of ageFirst postnatal dayDuctal closureProphylactic indomethacinApgar scoreNeurodevelopmental handicapParenchymal involvementPlacebo groupAdverse events
1993
Intraventricular Hemorrhage and Prematurity
Duncan C, Ment L. Intraventricular Hemorrhage and Prematurity. Neurosurgery Clinics Of North America 1993, 4: 727-734. PMID: 8241793, DOI: 10.1016/s1042-3680(18)30562-x.Peer-Reviewed Original ResearchConceptsIntraventricular hemorrhageRisk of hemorrhageCerebral blood flowGerminal matrix tissueDiagnostic imaging techniquesPosthemorrhagic hydrocephalusPreterm neonatesClinical manifestationsBlood flowVentricular systemHemorrhageCapillary bedMatrix tissueImaging techniquesPossible rupturePrematurityHydrocephalusNeonatesNeuropathologyParenchymaBrainRisk period for intraventricular hemorrhage of the preterm neonate is independent of gestational age.
Ment L, Oh W, Ehrenkranz R, Philip A, Schneider K, Katz K, Taylor K, Duncan C, Makuch R. Risk period for intraventricular hemorrhage of the preterm neonate is independent of gestational age. Seminars In Perinatology 1993, 17: 338-41. PMID: 8290976.Peer-Reviewed Original Research