2020
The emerging role of Janus kinase inhibitors in the treatment of autoimmune and inflammatory diseases
Damsky W, Peterson D, Ramseier J, Al-Bawardy B, Chun H, Proctor D, Strand V, Flavell RA, King B. The emerging role of Janus kinase inhibitors in the treatment of autoimmune and inflammatory diseases. Journal Of Allergy And Clinical Immunology 2020, 147: 814-826. PMID: 33129886, DOI: 10.1016/j.jaci.2020.10.022.BooksConceptsTranscription pathwayDownstream Janus kinaseJAK-signal transducerSmall molecule inhibitorsSignal transducerJanus kinaseJAK inhibitorsAutoimmune/inflammatory disordersKinase inhibitorsActivatorPathwayInhibitorsCytokine activityInflammatory diseasesImmune systemKinaseOrgan systemsBiologyCytokinesTransducerInhibition
2017
Endoscopic muscle biopsy sampling of the duodenum and rectum: a pilot survival study in a porcine model to detect myenteric neurons
Rajan E, Al-Bawardy B, Gostout CJ, Wong Kee Song LM, Deters JL, Knipschield MA, Bernard CE, Farrugia G. Endoscopic muscle biopsy sampling of the duodenum and rectum: a pilot survival study in a porcine model to detect myenteric neurons. Gastrointestinal Endoscopy 2017, 87: 600-606. PMID: 28734992, PMCID: PMC5775930, DOI: 10.1016/j.gie.2017.07.023.Peer-Reviewed Original ResearchConceptsMuscle biopsy samplingProtein gene product 9.5Myenteric neuronsMuscularis propriaGene product 9.5Biopsy samplingSnare electrocauteryUpper endoscopyProduct 9.5Scope clipDuodenal wallBand ligation techniqueFunctional bowel disordersSlow transit constipationProcedural adverse eventsRectal muscularis propriaIntermuscular layerAdverse eventsBowel disordersClinical courseMotility disordersSmall bowelSurgical approachTissue diagnosisPreclinical studies