2010
Escitalopram versus placebo in the treatment of dysthymic disorder
Hellerstein DJ, Batchelder ST, Hyler S, Arnaout B, Toba C, Benga I, Gangure D. Escitalopram versus placebo in the treatment of dysthymic disorder. International Clinical Psychopharmacology 2010, 25: 143-148. PMID: 21811192, DOI: 10.1097/yic.0b013e328333c35e.Peer-Reviewed Original ResearchConceptsHamilton Depression Rating ScaleDysthymic disorderGlobal assessmentSelective serotonin reuptake inhibitorsClinical Global Impressions-SeveritySuperiority of escitalopramPercentage of respondersPlacebo-treated individualsSerotonin reuptake inhibitorsDepression Rating ScaleStructured Clinical InterviewPercentage of participantsLarger study sampleItem total scoresSocial Adjustment ScaleAcute efficacyEscitalopram doseHDRS-24Active medicationReuptake inhibitorsWeek 12Inclusion criteriaSecondary measuresEscitalopramClinical Interview
2008
Does a History of Alcohol Use Disorder Affect Response to Antidepressant Medication in Patients With Dysthymic Disorder?
Arnaout B, Batchelder S, Rosenthal R, Hyler S, Hellerstein D. Does a History of Alcohol Use Disorder Affect Response to Antidepressant Medication in Patients With Dysthymic Disorder? Journal Of Dual Diagnosis 2008, 4: 377-393. DOI: 10.1080/15504260802086842.Peer-Reviewed Original ResearchLifetime alcohol use disorderAlcohol use disorderDysthymic disorderUse disordersBaseline Hamilton Depression Rating ScaleHamilton Depression Rating ScaleRating ScaleWeeks of treatmentWeeks of pharmacotherapyDepression Rating ScaleHDRS-24Medication trialsAlcoholic patientsAdult outpatientsRate of responseLifetime historySecondary analysisDisordersGreater decreaseRemissionPharmacotherapyPatientsAdequate evaluationTreatmentPreliminary findings