2009
Relation Between Amygdala Structure and Function in Adolescents With Bipolar Disorder
Kalmar JH, Wang F, Chepenik LG, Womer FY, Jones MM, Pittman B, Shah MP, Martin A, Constable RT, Blumberg HP. Relation Between Amygdala Structure and Function in Adolescents With Bipolar Disorder. Journal Of The American Academy Of Child & Adolescent Psychiatry 2009, 48: 636-642. PMID: 19454919, PMCID: PMC2867040, DOI: 10.1097/chi.0b013e31819f6fbc.Peer-Reviewed Original ResearchConceptsAmygdala volumeBipolar disorderInverse associationAmygdala structureMagnetic resonance imaging (MRI) scansAmygdala responseFunctional magnetic resonance imaging (fMRI) scansResonance imaging scansPossible pathophysiological linkSignificant inverse associationSmaller amygdala volumesFunctional magnetic resonancePathophysiological linkImaging scansBD groupHighest amygdala responseEmotional stimuliBD participantsElevated responseNeuroimaging sessionAdolescentsAmygdalaPrevious reportsPreliminary findingsDisorders
2005
Electrocardiographic Changes in Children and Adolescents Treated With Ziprasidone: A Prospective Study
BLAIR J, SCAHILL L, STATE M, MARTIN A. Electrocardiographic Changes in Children and Adolescents Treated With Ziprasidone: A Prospective Study. Journal Of The American Academy Of Child & Adolescent Psychiatry 2005, 44: 73-79. PMID: 15608546, DOI: 10.1097/01.chi.0000145372.61239.bb.Peer-Reviewed Original ResearchConceptsQTc intervalClose electrocardiographic monitoringMean QTc prolongationQTc-prolonging agentsOpen-label trialLonger QTc intervalsCurrent treatment standardsQRS complex widthZiprasidone dosePediatric outpatientsQTc prolongationElectrocardiographic changesElectrocardiographic monitoringProspective studyMean ageSafety profilePeak QTcHeart rateHigh dosesZiprasidoneTreatment standardsDoseDosesPreliminary findingsProlongation