2008
Reduction of Restraint and Seclusion Through Collaborative Problem Solving: A Five-Year Prospective Inpatient Study
Martin A, Krieg H, Esposito F, Stubbe D, Cardona L. Reduction of Restraint and Seclusion Through Collaborative Problem Solving: A Five-Year Prospective Inpatient Study. Psychiatric Services 2008, 59: 1406-1412. PMID: 19033167, DOI: 10.1176/ps.2008.59.12.1406.Peer-Reviewed Original ResearchConceptsMean durationRestraint useProspective inpatient studyChildren's psychiatric inpatient settingPsychiatric inpatient unitPsychiatric inpatient settingsUse of restraintsSeclusion eventsInpatient studySchool-aged childrenStaff injuriesInpatient settingInpatient unitPatient assaultsReduction of restraintsTherapeutic programClinical settingSeclusion useTransient increaseStudy periodFiscal year 2003ChildrenEarly phaseMonthsEpisodes
2006
Effects of Short- and Long-Term Risperidone Treatment on Prolactin Levels in Children with Autism
Anderson GM, Scahill L, McCracken JT, McDougle CJ, Aman MG, Tierney E, Arnold LE, Martin A, Katsovich L, Posey DJ, Shah B, Vitiello B. Effects of Short- and Long-Term Risperidone Treatment on Prolactin Levels in Children with Autism. Biological Psychiatry 2006, 61: 545-550. PMID: 16730335, DOI: 10.1016/j.biopsych.2006.02.032.Peer-Reviewed Original ResearchConceptsRisperidone-induced increasesLong-term risperidone treatmentProlactin levelsRisperidone treatmentSerum prolactinOpen-label followWeeks of risperidoneBaseline prolactin levelsEffects of ShortPlacebo groupProlactin elevationReceptor polymorphismsWeek 8Baseline levelsMean increaseProlactinRisperidoneSerum samplesAdverse effectsPlaceboChildrenTreatmentMonthsDRD2 allelesAdolescents