Characterizing Declines in Pediatric Antidepressant Use After New Risk Disclosures
Busch SH, Frank RG, Martin A, Barry CL. Characterizing Declines in Pediatric Antidepressant Use After New Risk Disclosures. Medical Care Research And Review 2010, 68: 96-111. PMID: 20675349, PMCID: PMC2974787, DOI: 10.1177/1077558710374197.Peer-Reviewed Original ResearchConceptsAntidepressant usePediatric antidepressant useAntidepressant medication useNew treatment episodeNew safety informationRisk of suicidalityAntidepressant medicationMedication useTreatment patternsTreatment episodesHealth outcomesLatter groupChildrenSafety informationFamily characteristicsCollege-educated parentsExperienced declinesMedicationsAntidepressantsDeclineFindingsSuicidalityAntidepressants and suicide risk: how did specific information in FDA safety warnings affect treatment patterns?
Busch SH, Frank RG, Leslie DL, Martin A, Rosenheck RA, Martin EG, Barry CL. Antidepressants and suicide risk: how did specific information in FDA safety warnings affect treatment patterns? Psychiatric Services 2010, 61: 11-6. PMID: 20044412, PMCID: PMC2801076, DOI: 10.1176/appi.ps.61.1.11.Peer-Reviewed Original ResearchConceptsMajor depressive disorderAntidepressant useTreatment patternsDepressive disorderFDA safety warningsSpecific safety informationThomson Reuters MarketScanUse of paroxetineRisk of suicidalitySafety warningsAntidepressant treatmentOutpatient visitsTreatment episodesTreatment recommendationsPractice patternsNew episodesDrug AdministrationSuicide riskFDA recommendationsDepressed childrenU.S. FoodFDAAntidepressantsChildrenEvidence of increases