2003
DRD4 exon III polymorphism and response to risperidone in Israeli adolescents with schizophrenia: a pilot pharmacogenetic study
Zalsman G, Frisch A, Lev-Ran S, Martin A, Michaelovsky E, Bensason D, Gothelf D, Nahshoni E, Tyano S, Weizman A. DRD4 exon III polymorphism and response to risperidone in Israeli adolescents with schizophrenia: a pilot pharmacogenetic study. European Neuropsychopharmacology 2003, 13: 183-185. PMID: 12729944, DOI: 10.1016/s0924-977x(03)00006-3.Peer-Reviewed Original ResearchConceptsBrief Psychiatric Rating ScalePossible associationAdolescent schizophrenia patientsFirst-episode schizophreniaPsychiatric Rating ScaleHigh response rateClinical responseRepeat alleleSchizophrenia patientsResponse rateSignificant associationPharmacogenetic studiesRisperidoneAdolescent inpatientsRating ScaleSchizophreniaAssociationDRD4 genotypeDRD4 geneResponseIsraeli adolescentsLarge groupPolymorphismDRD4 exon III polymorphismPatients
2002
Triglyceride, cholesterol and weight changes among risperidone-treated youths
Martin A, L'Ecuyer S. Triglyceride, cholesterol and weight changes among risperidone-treated youths. European Child & Adolescent Psychiatry 2002, 11: 129-133. PMID: 12369772, DOI: 10.1007/s00787-002-0255-5.Peer-Reviewed Original ResearchConceptsRisperidone-treated youthsMean ageWeight gainRetrospective chart reviewWeight changeRegular laboratory monitoringAtypical antipsychotic useSignificant weight gainSample mean ageChart reviewRisperidone doseAntipsychotic useSerum triglyceridesLaboratory monitoringTriglyceride levelsCholesterol levelsLipid dysregulationAdolescent inpatientsTriglyceridesPreliminary reportMeasures analysisSuch associationsCholesterolSignificant changesAverage length