C-Reactive Protein Testing for Active Tuberculosis among Inpatients without HIV in Uganda: a Diagnostic Accuracy Study
Meyer AJ, Ochom E, Turimumahoro P, Byanyima P, Sanyu I, Lalitha R, Kaswabuli S, Andama A, Walter ND, Katamba A, Cattamanchi A, Worodria W, Huang L, Yoon C, Davis JL. C-Reactive Protein Testing for Active Tuberculosis among Inpatients without HIV in Uganda: a Diagnostic Accuracy Study. Journal Of Clinical Microbiology 2020, 59: 10.1128/jcm.02162-20. PMID: 33087439, PMCID: PMC7771459, DOI: 10.1128/jcm.02162-20.Peer-Reviewed Original ResearchConceptsC-reactive proteinEnzyme-linked immunosorbent assayTriage testUtility of CRPC-reactive protein testingCulture-positive pulmonary tuberculosisProspective cross-sectional studySerum C-reactive proteinDiagnostic performanceHIV-seronegative individualsTB triage testNational Referral HospitalCross-sectional studyNegative predictive valueNegative likelihood ratioDiagnostic accuracy studiesActive tuberculosisPulmonary tuberculosisTB screeningReferral hospitalIllness severityCRP testingSputum samplesManufacturer's thresholdPredictive value