Sputum quality and diagnostic performance of GeneXpert MTB/RIF among smear-negative adults with presumed tuberculosis in Uganda
Meyer AJ, Atuheire C, Worodria W, Kizito S, Katamba A, Sanyu I, Andama A, Ayakaka I, Cattamanchi A, Bwanga F, Huang L, Davis JL. Sputum quality and diagnostic performance of GeneXpert MTB/RIF among smear-negative adults with presumed tuberculosis in Uganda. PLOS ONE 2017, 12: e0180572. PMID: 28686705, PMCID: PMC5501569, DOI: 10.1371/journal.pone.0180572.Peer-Reviewed Original ResearchMeSH KeywordsAdultCross-Sectional StudiesFemaleHumansMaleMicroscopyMolecular Diagnostic TechniquesMycobacterium tuberculosisProspective StudiesSputumTuberculosis, PulmonaryUgandaYoung AdultConceptsGeneXpert MTB/RIFBlood-stained sputumSputum qualityMTB/RIFSalivary sputumXpert testingDiagnostic performanceMycobacterial cultureCross-sectional studyTB patientsPatient factorsSputum testTB diagnosisDiagnostic yieldMucoid sputumSputum samplesLED fluorescence microscopySputumXpertTuberculosis diagnosticsDemographic informationPatientsAdditional testingHigher proportionSample types