Featured Publications
C-Reactive Protein Testing for Active Tuberculosis among Inpatients without HIV in Uganda: a Diagnostic Accuracy Study
Meyer AJ, Ochom E, Turimumahoro P, Byanyima P, Sanyu I, Lalitha R, Kaswabuli S, Andama A, Walter ND, Katamba A, Cattamanchi A, Worodria W, Huang L, Yoon C, Davis JL. C-Reactive Protein Testing for Active Tuberculosis among Inpatients without HIV in Uganda: a Diagnostic Accuracy Study. Journal Of Clinical Microbiology 2020, 59: 10.1128/jcm.02162-20. PMID: 33087439, PMCID: PMC7771459, DOI: 10.1128/jcm.02162-20.Peer-Reviewed Original ResearchConceptsC-reactive proteinEnzyme-linked immunosorbent assayTriage testUtility of CRPC-reactive protein testingCulture-positive pulmonary tuberculosisProspective cross-sectional studySerum C-reactive proteinDiagnostic performanceHIV-seronegative individualsTB triage testNational Referral HospitalCross-sectional studyNegative predictive valueNegative likelihood ratioDiagnostic accuracy studiesActive tuberculosisPulmonary tuberculosisTB screeningReferral hospitalIllness severityCRP testingSputum samplesManufacturer's thresholdPredictive valueSputum quality and diagnostic performance of GeneXpert MTB/RIF among smear-negative adults with presumed tuberculosis in Uganda
Meyer AJ, Atuheire C, Worodria W, Kizito S, Katamba A, Sanyu I, Andama A, Ayakaka I, Cattamanchi A, Bwanga F, Huang L, Davis JL. Sputum quality and diagnostic performance of GeneXpert MTB/RIF among smear-negative adults with presumed tuberculosis in Uganda. PLOS ONE 2017, 12: e0180572. PMID: 28686705, PMCID: PMC5501569, DOI: 10.1371/journal.pone.0180572.Peer-Reviewed Original ResearchConceptsGeneXpert MTB/RIFBlood-stained sputumSputum qualityMTB/RIFSalivary sputumXpert testingDiagnostic performanceMycobacterial cultureCross-sectional studyTB patientsPatient factorsSputum testTB diagnosisDiagnostic yieldMucoid sputumSputum samplesLED fluorescence microscopySputumXpertTuberculosis diagnosticsDemographic informationPatientsAdditional testingHigher proportionSample types
2018
‘Something so hard': a mixed-methods study of home sputum collection for tuberculosis contact investigation in Uganda
Armstrong-Hough M, Ggita J, Turimumahoro P, Meyer AJ, Ochom E, Dowdy D, Cattamanchi A, Katamba A, Davis JL. ‘Something so hard': a mixed-methods study of home sputum collection for tuberculosis contact investigation in Uganda. The International Journal Of Tuberculosis And Lung Disease 2018, 22: 1152-1159. PMID: 30236182, PMCID: PMC6496950, DOI: 10.5588/ijtld.18.0129.Peer-Reviewed Original ResearchConceptsLay health workersSputum collectionContact investigationHome-based collectionTB contact investigationContacts of patientsTuberculosis contact investigationDiagnosis of tuberculosisActive tuberculosisPrompt evaluationRisk factorsEnhanced interventionsIndex patientsConvergent mixed-methods studyHealth workersHome visitsSputumClinical settingTuberculosisMixed-methods studyMixed-method studyPatientsContact interviewsFocus group discussionsIntervention