2023
Amniotic fluid cortisol predicts neonatal and infant development in non-stressed rhesus monkeys: Implications for prenatal stress
Otridge J, Meyer J, Dettmer A. Amniotic fluid cortisol predicts neonatal and infant development in non-stressed rhesus monkeys: Implications for prenatal stress. Neurotoxicology And Teratology 2023, 100: 107308. PMID: 37890675, PMCID: PMC10872548, DOI: 10.1016/j.ntt.2023.107308.Peer-Reviewed Original ResearchConceptsHair cortisol concentrationsCORT exposureInfant developmentPrenatal stressMaternal hair cortisol concentrationsAmniotic fluid cortisolInfant hair cortisol concentrationsFetal cortisol exposurePostnatal day 30Healthy rhesus macaquesInfant growth rateHealthy primatesGestational ageClinical reasonsCortisol exposureDays gestationNeonatal assessmentSensorimotor scoresAmniotic fluidNeurological developmentCortisol concentrationsDay 30Rhesus monkeysRhesus macaquesCORT levelsAre hair cortisol levels dependent on hair growth rate? A pilot study in rhesus macaques
Dettmer A, Novak M, Meyer J. Are hair cortisol levels dependent on hair growth rate? A pilot study in rhesus macaques. General And Comparative Endocrinology 2023, 340: 114308. PMID: 37244411, PMCID: PMC10330586, DOI: 10.1016/j.ygcen.2023.114308.Peer-Reviewed Original ResearchConceptsHair cortisol concentrationsHair growth rateHair growthMacaque monkeysCortisol accumulationPilot studyAccumulation of cortisolHPA axis regulationLower hair cortisol concentrationsHigher hair cortisol concentrationsGlucocorticoid-mediated inhibitionPresent pilot studyRhesus macaque monkeysAdult female macaquesHair cortisol levelsAge-related differencesAxis regulationHair samplesInfants 3Rodent studiesCortisol levelsCortisol concentrationsAge groupsCortisol studiesNonhuman primate species
2022
Early life adversity and males: Biology, behavior, and implications for fathers’ parenting
Condon EM, Dettmer A, Baker E, McFaul C, Stover CS. Early life adversity and males: Biology, behavior, and implications for fathers’ parenting. Neuroscience & Biobehavioral Reviews 2022, 135: 104531. PMID: 35063493, PMCID: PMC9236197, DOI: 10.1016/j.neubiorev.2022.104531.Peer-Reviewed Original ResearchConceptsEarly life adversityFathers' parentingLife adversityNon-human animal literatureEffects of ELANeurocognitive functioningChild developmentAnimal literatureLittle empirical researchParentingUnique influenceIntergenerational transmissionIntervention developmentBehavioral pathwaysFuture researchAdversityEmpirical researchConceptual modelGene-environment interactionsFathersEmpirical studyHormone receptorsNeurobiologyFunctioningMales
2019
Impacts of early social experience on cognitive development in infant rhesus macaques
Murphy AM, Dettmer AM. Impacts of early social experience on cognitive development in infant rhesus macaques. Developmental Psychobiology 2019, 62: 895-908. PMID: 31531855, DOI: 10.1002/dev.21916.Peer-Reviewed Original ResearchConceptsCognitive developmentEarly social experienceNR infantsInfant rhesus macaquesSocial experienceNeonatal neurobehavioral assessmentEarly life experiencesCognitive flexibilityCognitive tasksReward associationsAffective reactivityCognitive differencesChild developmentLife experiencesImpulsivityNeurobehavioral assessmentTaskMonths of ageRhesus macaquesExperienceScant literatureTemperamentEarly rearingNeurobiologyInfantsDominance rank predicts social network position across developmental stages in rhesus monkeys
Wooddell LJ, Kaburu SSK, Dettmer AM. Dominance rank predicts social network position across developmental stages in rhesus monkeys. American Journal Of Primatology 2019, 82: e23024. PMID: 31240764, DOI: 10.1002/ajp.23024.Peer-Reviewed Original ResearchA descriptive analysis of gut microbiota composition in differentially reared infant rhesus monkeys (Macaca mulatta) across the first 6 months of life
Dettmer AM, Allen JM, Jaggers RM, Bailey MT. A descriptive analysis of gut microbiota composition in differentially reared infant rhesus monkeys (Macaca mulatta) across the first 6 months of life. American Journal Of Primatology 2019, 81: e22969. PMID: 30941799, PMCID: PMC6774917, DOI: 10.1002/ajp.22969.Peer-Reviewed Original ResearchConceptsGut microbiota compositionMonths of lifeInfant rhesus monkeysMicrobiota compositionRhesus monkeysEarly life experiencesPostnatal day 14Gut microbial colonizationDay of birthHost immune functionNR infantsFed formulaClinical significanceImmune functionRectal swabsDaily social contactsDay 180Gut microbiotaDay 14Subsequent healthInfantsGastrointestinal microbiomeGut microbiomeSocial contactNovel findings
2018
Interindividual differences in neonatal sociality and emotionality predict juvenile social status in rhesus monkeys
Wooddell LJ, Simpson EA, Murphy AM, Dettmer AM, Paukner A. Interindividual differences in neonatal sociality and emotionality predict juvenile social status in rhesus monkeys. Developmental Science 2018, 22: e12749. PMID: 30171780, PMCID: PMC10519424, DOI: 10.1111/desc.12749.Peer-Reviewed Original ResearchConceptsEarly social experienceSocial experienceEmotional reactivityNeonatal imitationLater social outcomesPeer social groupsSocio-emotional developmentSocial statusInterindividual differencesInfants' first weekImitation testSocioeconomic statusSocial outcomesSocial relationshipsMaternal social statusLittle researchProfound outcomesHigh social statusSocial groupsImitationLongitudinal natureReactivity assessmentRhesus monkeysInfant dyadsSociality
2017
Sex and rank affect how infant rhesus macaques look at faces
Paukner A, Slonecker EM, Murphy AM, Wooddell LJ, Dettmer AM. Sex and rank affect how infant rhesus macaques look at faces. Developmental Psychobiology 2017, 60: 187-193. PMID: 29165801, PMCID: PMC5815906, DOI: 10.1002/dev.21579.Peer-Reviewed Original ResearchRank acquisition in rhesus macaque yearlings following permanent maternal separation: The importance of the social and physical environment
Wooddell LJ, Kaburu SSK, Murphy AM, Suomi SJ, Dettmer AM. Rank acquisition in rhesus macaque yearlings following permanent maternal separation: The importance of the social and physical environment. Developmental Psychobiology 2017, 59: 863-875. PMID: 28833057, PMCID: PMC5630511, DOI: 10.1002/dev.21555.Peer-Reviewed Original ResearchConceptsRank acquisitionEarly social experienceSocial affiliationBehavioral developmentSocial experienceSignificant rank changesDevelopmental milestonesFamiliar environmentIndividual traitsPhysical environmentSocial rankBody of literatureMaternal separationSocial groupsSocial asymmetriesAcquisitionDominance acquisitionRelationships between affiliative social behavior and hair cortisol concentrations in semi-free ranging rhesus monkeys
Wooddell LJ, Hamel AF, Murphy AM, Byers KL, Kaburu SSK, Meyer JS, Suomi SJ, Dettmer AM. Relationships between affiliative social behavior and hair cortisol concentrations in semi-free ranging rhesus monkeys. Psychoneuroendocrinology 2017, 84: 109-115. PMID: 28700960, PMCID: PMC5555374, DOI: 10.1016/j.psyneuen.2017.06.018.Peer-Reviewed Original ResearchElo-rating for Tracking Rank Fluctuations after Demographic Changes Involving Semi-free-ranging Rhesus Macaques (Macaca mulatta).
Wooddell LJ, Kaburu SS, Suomi SJ, Dettmer AM. Elo-rating for Tracking Rank Fluctuations after Demographic Changes Involving Semi-free-ranging Rhesus Macaques (Macaca mulatta). Journal Of The American Association For Laboratory Animal Science 2017, 56: 260-268. PMID: 28535861, PMCID: PMC5438919.Peer-Reviewed Original ResearchCortisol in Neonatal Mother's Milk Predicts Later Infant Social and Cognitive Functioning in Rhesus Monkeys
Dettmer AM, Murphy AM, Guitarra D, Slonecker E, Suomi SJ, Rosenberg KL, Novak MA, Meyer JS, Hinde K. Cortisol in Neonatal Mother's Milk Predicts Later Infant Social and Cognitive Functioning in Rhesus Monkeys. Child Development 2017, 89: 525-538. PMID: 28369689, PMCID: PMC6528802, DOI: 10.1111/cdev.12783.Peer-Reviewed Original Research
2016
Early life adversity alters normal sex-dependent developmental dynamics of DNA methylation
Massart R, Nemoda Z, Suderman MJ, Sutti S, Ruggiero AM, Dettmer AM, Suomi SJ, Szyf M. Early life adversity alters normal sex-dependent developmental dynamics of DNA methylation. Development And Psychopathology 2016, 28: 1259-1272. PMID: 27687908, PMCID: PMC6590057, DOI: 10.1017/s0954579416000833.Peer-Reviewed Original ResearchConceptsDNA methylation profilesDNA methylation changesMethylation profilesMethylation changesGenome-wide DNA methylation changesEpigenetic programsDevelopmental evolutionEpigenetic processesDNA methylationAdult phenotypeDevelopmental dynamicsNormal evolutionGenesMethylationEvolutionPhenotypeEarly life eventsEarly life experiencesEffects of sexFemalesEarly life adversityT lymphocytesNonhuman primatesRodentsPrimatesNeonatal face-to-face interactions promote later social behaviour in infant rhesus monkeys
Dettmer AM, Kaburu SS, Simpson EA, Paukner A, Sclafani V, Byers KL, Murphy AM, Miller M, Marquez N, Miller GM, Suomi SJ, Ferrari PF. Neonatal face-to-face interactions promote later social behaviour in infant rhesus monkeys. Nature Communications 2016, 7: 11940. PMID: 27300086, PMCID: PMC4911675, DOI: 10.1038/ncomms11940.Peer-Reviewed Original ResearchRhesus macaques (Macaca mulatta) with self‐injurious behavior show less behavioral anxiety during the human intruder test
Peterson EJ, Worlein JM, Lee GH, Dettmer AM, Varner EK, Novak MA. Rhesus macaques (Macaca mulatta) with self‐injurious behavior show less behavioral anxiety during the human intruder test. American Journal Of Primatology 2016, 79: 1-8. PMID: 27286311, PMCID: PMC7652060, DOI: 10.1002/ajp.22569.Peer-Reviewed Original ResearchMatrilineal Behavioral and Physiological Changes following the Death of a Non-Alpha Matriarch in Rhesus Macaques (Macaca mulatta)
Wooddell LJ, Kaburu SS, Rosenberg KL, Meyer JS, Suomi SJ, Dettmer AM. Matrilineal Behavioral and Physiological Changes following the Death of a Non-Alpha Matriarch in Rhesus Macaques (Macaca mulatta). PLOS ONE 2016, 11: e0157108. PMID: 27275743, PMCID: PMC4898773, DOI: 10.1371/journal.pone.0157108.Peer-Reviewed Original Research
2015
First‐time rhesus monkey mothers, and mothers of sons, preferentially engage in face‐to‐face interactions with their infants
Dettmer AM, Kaburu SS, Byers KL, Murphy AM, Soneson E, Wooddell LJ, Suomi SJ. First‐time rhesus monkey mothers, and mothers of sons, preferentially engage in face‐to‐face interactions with their infants. American Journal Of Primatology 2015, 78: 238-246. PMID: 26581804, PMCID: PMC6528797, DOI: 10.1002/ajp.22503.Peer-Reviewed Original ResearchAssociations between Parity, Hair Hormone Profiles during Pregnancy and Lactation, and Infant Development in Rhesus Monkeys (Macaca mulatta)
Dettmer AM, Rosenberg KL, Suomi SJ, Meyer JS, Novak MA. Associations between Parity, Hair Hormone Profiles during Pregnancy and Lactation, and Infant Development in Rhesus Monkeys (Macaca mulatta). PLOS ONE 2015, 10: e0131692. PMID: 26172048, PMCID: PMC4501543, DOI: 10.1371/journal.pone.0131692.Peer-Reviewed Original ResearchConceptsInfant developmentHormonal profileNeurobehavioral developmentRhesus monkeysFirst monthInfant neurobehavioral developmentEarly postnatal periodStage of pregnancyFemale rhesus monkeysPregnancy/lactationInfluence of parityPoor developmental outcomesNon-human primatesReflex scoresMaternal cortisolInfant exposureHormonal changesSensorimotor scoresPostnatal periodHormone profilesHormone concentrationsPrimiparous mothersPregnancyHormone productionEndocrine activityDevelopment of a cognitive testing apparatus for socially housed mother‐peer‐reared infant rhesus monkeys
Dettmer AM, Murphy AM, Suomi SJ. Development of a cognitive testing apparatus for socially housed mother‐peer‐reared infant rhesus monkeys. Developmental Psychobiology 2015, 57: 349-355. PMID: 25782609, PMCID: PMC4380797, DOI: 10.1002/dev.21285.Peer-Reviewed Original Research
2014
Reproductive consequences of a matrilineal overthrow in rhesus monkeys
Dettmer AM, Woodward RA, Suomi SJ. Reproductive consequences of a matrilineal overthrow in rhesus monkeys. American Journal Of Primatology 2014, 77: 346-352. PMID: 25382028, PMCID: PMC4334670, DOI: 10.1002/ajp.22350.Peer-Reviewed Original Research