2017
Role of Low Endothelial Shear Stress and Plaque Characteristics in the Prediction of Nonculprit Major Adverse Cardiac Events The PROSPECT Study
Stone PH, Maehara A, Coskun AU, Maynard CC, Zaromytidou M, Siasos G, Andreou I, Fotiadis D, Stefanou K, Papafaklis M, Michalis L, Lansky AJ, Mintz GS, Serruys PW, Feldman CL, Stone GW. Role of Low Endothelial Shear Stress and Plaque Characteristics in the Prediction of Nonculprit Major Adverse Cardiac Events The PROSPECT Study. JACC Cardiovascular Imaging 2017, 11: 462-471. PMID: 28917684, DOI: 10.1016/j.jcmg.2017.01.031.Peer-Reviewed Original ResearchMeSH KeywordsCoronary AngiographyCoronary Artery DiseaseCoronary CirculationCoronary VesselsDisease ProgressionEndothelium, VascularEuropeHumansPercutaneous Coronary InterventionPilot ProjectsPlaque, AtheroscleroticPredictive Value of TestsProspective StudiesRisk AssessmentRisk FactorsStress, MechanicalTime FactorsTreatment OutcomeUltrasonography, InterventionalUnited StatesConceptsMajor adverse cardiac eventsLow endothelial shear stressMinimum lumen areaAcute coronary syndromeEndothelial shear stressAdverse cardiac eventsPlaque burdenCoronary lesionsNC-MACECardiac eventsAnatomic riskNC lesionsFuture major adverse cardiac eventsHigh-risk acute coronary syndromesBaseline endothelial shear stressHuman-like animal modelsPrevious natural history studiesPropensity-adjusted Cox regressionSmaller minimum lumen areaPROSPECT studyLocal endothelial shear stressHigh anatomic riskHigh endothelial shear stressNonculprit coronary lesionsHigh-risk patients
2006
Intravascular Ultrasonic Differences Between Aorto-Ostial and Shaft Narrowing in Saphenous Veins Used as Aortocoronary Bypass Grafts
Sano K, Mintz GS, Carlier SG, Fujii K, Yasuda T, Kimura M, Costa JR, Costa RA, Lui J, Weisz G, Moussa I, Dangas GD, Mehran R, Lansky AJ, Kreps EM, Collins M, Stone GW, Moses JW, Leon MB. Intravascular Ultrasonic Differences Between Aorto-Ostial and Shaft Narrowing in Saphenous Veins Used as Aortocoronary Bypass Grafts. The American Journal Of Cardiology 2006, 97: 1463-1466. PMID: 16679084, DOI: 10.1016/j.amjcard.2005.11.080.Peer-Reviewed Original ResearchConceptsMinimal lumen areaAorto-ostial lesionsPositive remodelingShaft lesionsLumen areaPlaque burdenDistal referenceSoft plaqueAortocoronary bypass graftsLarger plaque burdenSVG lesionsComplication rateBypass graftInterventional complicationsSaphenous veinLesion locationLesionsMorphologic differencesRemodelingPlaquesIVUS dataLocation-specific differencesBurdenIntravascular ultrasound imagesPrevious studies
2003
Optimal final lumen area and predictors of target lesion revascularization after stent implantation in small coronary arteries
Iakovou I, Mintz GS, Dangas G, Abizaid A, Mehran R, Lansky AJ, Kobayashi Y, Hirose M, Ashby DT, Stone GW, Moses JW, Leon MB. Optimal final lumen area and predictors of target lesion revascularization after stent implantation in small coronary arteries. The American Journal Of Cardiology 2003, 92: 1171-1176. PMID: 14609591, DOI: 10.1016/j.amjcard.2003.07.025.Peer-Reviewed Original ResearchConceptsTarget lesion revascularizationGreater stent expansionSmall coronary arteriesCoronary arteryLesion revascularizationTLR rateStent implantationStent areaSmall vesselsPredictors of TLRAngiographic reference vessel diameterGroup IStent expansionLumen areaHigher TLR rateGroup II patientsBaseline patient characteristicsReference vessel diameterPrior myocardial infarctionEarly clinical eventsReference vessel areaFinal lumen areaHospital outcomesClinical restenosisPatient characteristics