2011
Intravascular Ultrasound Findings of Early Stent Thrombosis After Primary Percutaneous Intervention in Acute Myocardial Infarction
Choi SY, Witzenbichler B, Maehara A, Lansky AJ, Guagliumi G, Brodie B, Kellett MA, Dressler O, Parise H, Mehran R, Dangas GD, Mintz GS, Stone GW. Intravascular Ultrasound Findings of Early Stent Thrombosis After Primary Percutaneous Intervention in Acute Myocardial Infarction. Circulation Cardiovascular Interventions 2011, 4: 239-247. PMID: 21586693, DOI: 10.1161/circinterventions.110.959791.Peer-Reviewed Original ResearchConceptsEarly stent thrombosisMinimum lumen areaSignificant residual stenosisStent thrombosisAcute myocardial infarctionResidual stenosisEdge dissectionLumen areaAcute malappositionMyocardial infarctionTissue protrusionAcute Myocardial Infarction StudyIntravascular ultrasound predictorsSignificant edge dissectionPrimary percutaneous interventionIntravascular ultrasound findingsMyocardial Infarction StudyStent edge dissectionFinal lumen areaSmaller stent areaFormal substudyHarmonizing OutcomesIVUS predictorsOutflow diseaseStable angina
2006
Racial Differences Among High-Risk Patients Presenting With Non–ST-Segment Elevation Acute Coronary Syndromes (Results from the SYNERGY Trial)††Disclosure: Drs. Mahaffey, Cohen, Newby, Ferguson, and Califf have received honoria for speaking from sanofi-aventis. Drs. Mahaffey, Ferguson, and Califf have acted as consultants for sanofi-aventis. Drs. Echols, Velazquez, Santos, and Gurfinkel have no financial relationships to disclose.
Echols MR, Mahaffey KW, Banerjee A, Pieper KS, Stebbins A, Lansky A, Cohen MG, Velazquez E, Santos R, Newby LK, Gurfinkel EP, Biasucci L, Ferguson JJ, Califf RM. Racial Differences Among High-Risk Patients Presenting With Non–ST-Segment Elevation Acute Coronary Syndromes (Results from the SYNERGY Trial)††Disclosure: Drs. Mahaffey, Cohen, Newby, Ferguson, and Califf have received honoria for speaking from sanofi-aventis. Drs. Mahaffey, Ferguson, and Califf have acted as consultants for sanofi-aventis. Drs. Echols, Velazquez, Santos, and Gurfinkel have no financial relationships to disclose. The American Journal Of Cardiology 2006, 99: 315-321. PMID: 17261389, DOI: 10.1016/j.amjcard.2006.08.031.Peer-Reviewed Original ResearchConceptsAcute coronary syndromeAfrican American patientsMyocardial infarctionWhite patientsCoronary syndromeSegment elevation (NSTE) ACSST-segment elevation acute coronary syndromeElevation acute coronary syndromeBaseline clinical characteristicsFrequency of hypertensionNonfatal myocardial infarctionThirty-day deathCoronary artery bypassHigh-risk patientsOutcomes of patientsSanofi-AventisPercutaneous coronary interventionUse of angiographyNorth American patientsRacial differencesAfrican AmericansSYNERGY trialArtery bypassClinical characteristicsCoronary interventionOutcome After Acute Incomplete Sirolimus-Eluting Stent Apposition as Assessed by Serial Intravascular Ultrasound
Kimura M, Mintz GS, Carlier S, Takebayashi H, Fujii K, Sano K, Yasuda T, Costa RA, Costa JR, Quen J, Tanaka K, Lui J, Weisz G, Moussa I, Dangas G, Mehran R, Lansky AJ, Kreps EM, Collins M, Stone GW, Moses JW, Leon MB. Outcome After Acute Incomplete Sirolimus-Eluting Stent Apposition as Assessed by Serial Intravascular Ultrasound. The American Journal Of Cardiology 2006, 98: 436-442. PMID: 16893693, DOI: 10.1016/j.amjcard.2006.02.050.Peer-Reviewed Original ResearchConceptsIncomplete stent appositionSES implantationStent appositionSirolimus-eluting stent implantationComplete resolution groupIntravascular ultrasound findingsIncidence of restenosisSerial intravascular ultrasoundConsecutive patientsStent thrombosisStent implantationUltrasound findingsPlaque areaAneurysm formationStent restenosisIntravascular ultrasoundPatientsLumen areaStent strutsGreater decreaseVessel wallThrombosisRestenosisLesionsGreater increase
2003
Impact of Renal Insufficiency in Patients Undergoing Primary Angioplasty for Acute Myocardial Infarction
Sadeghi HM, Stone GW, Grines CL, Mehran R, Dixon SR, Lansky AJ, Fahy M, Cox DA, Garcia E, Tcheng JE, Griffin JJ, Stuckey TD, Turco M, Carroll JD. Impact of Renal Insufficiency in Patients Undergoing Primary Angioplasty for Acute Myocardial Infarction. Circulation 2003, 108: 2769-2775. PMID: 14638545, DOI: 10.1161/01.cir.0000103623.63687.21.Peer-Reviewed Original ResearchMeSH KeywordsAbciximabAcute DiseaseAgedAngioplasty, Balloon, CoronaryAntibodies, MonoclonalContrast MediaCoronary RestenosisCreatinineFemaleHumansImmunoglobulin Fab FragmentsMaleMiddle AgedMyocardial InfarctionPlatelet Aggregation InhibitorsPredictive Value of TestsPrognosisProspective StudiesRenal InsufficiencyRisk AssessmentStentsSurvival RateTreatment OutcomeConceptsPrimary percutaneous coronary interventionAcute myocardial infarctionBaseline renal insufficiencyRenal insufficiencyBaseline CrClMyocardial infarctionPrimary PCIPeripheral vascular diseasePowerful independent predictorPercutaneous coronary interventionRisk of mortalityTransfusion requirementsHemorrhagic complicationsPrimary angioplastySevere restenosisArtery reocclusionCoronary interventionCreatinine clearanceSymptom onsetHeart failureIndependent predictorsAMI patientsCerebrovascular diseasePoor prognosisPrognostic importanceIntravascular Ultrasound Assessment of Ulcerated Ruptured Plaques
Fujii K, Kobayashi Y, Mintz GS, Takebayashi H, Dangas G, Moussa I, Mehran R, Lansky AJ, Kreps E, Collins M, Colombo A, Stone GW, Leon MB, Moses JW. Intravascular Ultrasound Assessment of Ulcerated Ruptured Plaques. Circulation 2003, 108: 2473-2478. PMID: 14610010, DOI: 10.1161/01.cir.0000097121.95451.39.Peer-Reviewed Original ResearchConceptsNon-ACS patientsACS patientsAcute coronary syndromeCulprit lesionPlaque ruptureNonculprit lesionsSmaller lumen areaLumen areaPlaque burdenArea stenosisSmaller minimum lumen areaCulprit plaque ruptureGreater plaque burdenIntravascular ultrasound findingsPresence of thrombusIntravascular ultrasound assessmentMinimum lumen areaMinimal lumen siteCoronary syndromeRemodeling indexIndependent predictorsUltrasound assessmentUltrasound findingsRuptured plaquesPatients