2015
Will this trial change my practice? TOTAL: a randomised trial of thrombus aspiration in ST-elevation myocardial infarction.
Behan MW, Haude M, Oldroyd KG, Lansky AJ, James S, Baumbach A. Will this trial change my practice? TOTAL: a randomised trial of thrombus aspiration in ST-elevation myocardial infarction. EuroIntervention 2015, 11: 361-3. PMID: 26196756, DOI: 10.4244/eijv11i3a70.Peer-Reviewed Original Research
2014
Will this trial change my practice? TASTE - a randomised registry on thrombus aspiration in primary PCI with a 30-day endpoint.
Behan MW, Lansky AJ, Jolly S, Baumbach A. Will this trial change my practice? TASTE - a randomised registry on thrombus aspiration in primary PCI with a 30-day endpoint. EuroIntervention 2014, 10: 406-7. PMID: 25042270, DOI: 10.4244/eijv10i3a68.Peer-Reviewed Original Research
2011
Rationale and design of the INFUSE-AMI study: A 2 × 2 factorial, randomized, multicenter, single-blind evaluation of intracoronary abciximab infusion and aspiration thrombectomy in patients undergoing percutaneous coronary intervention for anterior ST-segment elevation myocardial infarction
Gibson CM, Maehara A, Lansky AJ, Wohrle J, Stuckey T, Dave R, Cox D, Grines C, Dudek D, Steg G, Parise H, Wolff SD, Cristea E, Stone GW. Rationale and design of the INFUSE-AMI study: A 2 × 2 factorial, randomized, multicenter, single-blind evaluation of intracoronary abciximab infusion and aspiration thrombectomy in patients undergoing percutaneous coronary intervention for anterior ST-segment elevation myocardial infarction. American Heart Journal 2011, 161: 478-486.e7. PMID: 21392601, DOI: 10.1016/j.ahj.2010.10.006.Peer-Reviewed Original ResearchMeSH KeywordsAbciximabAngioplasty, Balloon, CoronaryAntibodies, MonoclonalAntithrombinsCoronary OcclusionCoronary ThrombosisEndpoint DeterminationHirudinsHumansImmunoglobulin Fab FragmentsInfusions, Intra-ArterialMagnetic Resonance Imaging, CineMyocardial InfarctionPatient SelectionPeptide FragmentsPlatelet Aggregation InhibitorsRecombinant ProteinsResearch DesignThrombectomyConceptsPrimary percutaneous coronary interventionST-elevation myocardial infarctionPrimary PCIAnterior ST-elevation myocardial infarctionExport aspiration catheterPercutaneous coronary interventionLocal infusionThrombus aspirationInfarct sizeINFUSE-AMIEnd pointCoronary interventionAspiration catheterMyocardial infarctionInfusion catheterAnterior ST-segment elevation myocardial infarctionST-segment elevation myocardial infarctionSingle-blind randomized studyCardiac magnetic resonance imagingMyocardial infarction 0Mid-left anteriorPrimary end pointSafety end pointSecondary end pointsST-segment resolution
2007
Prospective, Multicenter Study of Thrombectomy in Patients with Acute Myocardial Infarction: The X‐Tract AMI Registry
YOUNG JJ, COX DA, STUCKEY T, BABB J, TURCO M, LANSKY AJ, MEHRAN R, STONE GW. Prospective, Multicenter Study of Thrombectomy in Patients with Acute Myocardial Infarction: The X‐Tract AMI Registry. Journal Of Interventional Cardiology 2007, 20: 44-50. PMID: 17300402, DOI: 10.1111/j.1540-8183.2007.00223.x.Peer-Reviewed Original ResearchMeSH KeywordsAngioplasty, Balloon, CoronaryCanadaCardiac CatheterizationCoronary ThrombosisCoronary VesselsFemaleGraft Occlusion, VascularHumansMaleMiddle AgedMyocardial InfarctionMyocardial ReperfusionPostoperative ComplicationsProspective StudiesRegistriesSaphenous VeinSeverity of Illness IndexStentsThrombectomyTreatment OutcomeUnited StatesConceptsSaphenous vein graftsAcute myocardial infarctionNative coronary arteriesPrimary angioplastyCoronary arteryAMI registryMulticenter studyMyocardial infarctionGlycoprotein IIb/IIIa inhibitorsMyocardial blush grade 3IIb/IIIa inhibitorsDiseased saphenous vein graftsTIMI 0/1 flowMajor cardiovascular eventsTIMI 3 flowMajority of patientsEpicardial blood flowBare metal stentsCardiovascular eventsThrombectomy systemDistal embolizationMulticenter experienceThromboembolic complicationsVein graftsMyocardial blush
2003
Prospective, randomized evaluation of thrombectomy prior to percutaneous intervention in diseased saphenous vein grafts and thrombus-containing coronary arteries
Stone GW, Cox DA, Babb J, Nukta D, Bilodeau L, Cannon L, Stuckey TD, Hermiller J, Cohen EA, Low R, Bailey SR, Lansky AJ, Kuntz RE, Investigators F. Prospective, randomized evaluation of thrombectomy prior to percutaneous intervention in diseased saphenous vein grafts and thrombus-containing coronary arteries. Journal Of The American College Of Cardiology 2003, 42: 2007-2013. PMID: 14662267, DOI: 10.1016/j.jacc.2003.10.001.Peer-Reviewed Original ResearchConceptsDiseased saphenous vein graftsSaphenous vein graftsNative coronary arteriesPeri-procedural myocardial infarctionEvent-free survivalCoronary arteryMyocardial infarctionControl patientsStent implantationRoutine thrombectomyVein graftsSize patientsLate event-free survivalMajor adverse cardiac eventsPeri-procedural myonecrosisAdverse cardiac eventsHigh-risk patientsPercutaneous coronary interventionLarge myocardial infarctionSafety of interventionsPrior thrombectomyCardiac eventsCoronary interventionPercutaneous interventionLate outcomesSafety and efficacy of a novel device for treatment of thrombotic and atherosclerotic lesions in native coronary arteries and saphenous vein grafts: Results from the multicenter X‐sizer for treatment of thrombus and atherosclerosis in coronary applications trial (X‐TRACT) study
Stone GW, Cox DA, Low R, Cates CU, Satler L, Bailey SR, Kuntz RE, Lansky AJ. Safety and efficacy of a novel device for treatment of thrombotic and atherosclerotic lesions in native coronary arteries and saphenous vein grafts: Results from the multicenter X‐sizer for treatment of thrombus and atherosclerosis in coronary applications trial (X‐TRACT) study. Catheterization And Cardiovascular Interventions 2003, 58: 419-427. PMID: 12652487, DOI: 10.1002/ccd.10511.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryAtherectomy, CoronaryChi-Square DistributionCoronary AngiographyCoronary Artery DiseaseCoronary ThrombosisEquipment DesignEquipment SafetyFemaleFollow-Up StudiesGraft Occlusion, VascularHumansMaleMiddle AgedProbabilityRisk AssessmentSaphenous VeinStatistics, NonparametricStentsThrombectomyTreatment OutcomeConceptsSaphenous vein graftsNative coronary arteriesVein graftsX-SizerThrombotic lesionsCoronary arteryNon-Q-wave MIDistal branch occlusionTIMI 3 flowSide branch occlusionTreatment of thrombusDistal thromboemboliPeriprocedural MITIMI 0Adverse eventsThromboembolic complicationsConsecutive patientsAntegrade flowBranch occlusionPercutaneous interventionHistorical controlsAtherosclerotic lesionsTrial studyU.S. CentersLesions
2002
A trial comparing rheolytic thrombectomy with intracoronary urokinase for coronary and vein graft thrombus (the Vein Graft AngioJet Study [VeGAS 2])
Kuntz RE, Baim DS, Cohen DJ, Popma JJ, Carrozza JP, Sharma S, McCormick DJ, Schmidt DA, Lansky AJ, Ho KK, Dandreo KJ, Setum CM, Ramee SR, Investigators V. A trial comparing rheolytic thrombectomy with intracoronary urokinase for coronary and vein graft thrombus (the Vein Graft AngioJet Study [VeGAS 2]). The American Journal Of Cardiology 2002, 89: 326-330. PMID: 11809436, DOI: 10.1016/s0002-9149(01)02235-4.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAngioplasty, Balloon, CoronaryCoronary AngiographyCoronary ThrombosisDisease-Free SurvivalFemaleFibrinolytic AgentsGraft Occlusion, VascularHemorheologyHumansInfusions, Intra-ArterialMaleMiddle AgedThrombectomyTreatment OutcomeUnited StatesUrokinase-Type Plasminogen Activator
2001
Rheolytic thrombectomy during percutaneous revascularization for acute myocardial infarction: Experience with the AngioJet catheter
Silva J, Ramee S, Cohen D, Carrozza J, Popma J, Lansky A, Dandreo K, Baim D, George B, McCormick D, Setum C, Kuntz R. Rheolytic thrombectomy during percutaneous revascularization for acute myocardial infarction: Experience with the AngioJet catheter. American Heart Journal 2001, 141: 353-359. PMID: 11231431, DOI: 10.1067/mhj.2001.112997.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionImmediate definitive treatmentMyocardial infarctionRheolytic thrombectomyDefinitive treatmentDistal embolizationBalloon angioplastyFinal TIMI 3 flowAngioJet rheolytic thrombectomySubsequent definitive treatmentHospital mortality rateTIMI 3 flowMajor adverse eventsThrombus-containing lesionsMechanical thrombectomy devicesEvident thrombusPercutaneous revascularizationAdverse eventsAdjunctive treatmentProcedural complicationsAngioJet catheterClinical outcomesCoronary flowProcedure successThrombectomy devices
1998
Rheolytic thrombectomy in the treatment of acute limb‐threatening ischemia: Immediate results and six‐month follow‐up of the multicenter AngioJet® registry
Silva J, Ramee S, Collins T, Jenkins J, Lansky A, Ansel G, Dolmatch B, Glickman M, Stainken B, Ramee E, White C. Rheolytic thrombectomy in the treatment of acute limb‐threatening ischemia: Immediate results and six‐month follow‐up of the multicenter AngioJet® registry. Catheterization And Cardiovascular Interventions 1998, 45: 386-393. PMID: 9863742, DOI: 10.1002/(sici)1097-0304(199812)45:4<386::aid-ccd7>3.0.co;2-q.Peer-Reviewed Original ResearchConceptsLimb-threatening ischemiaAcute limb-threatening ischemiaRheolytic thrombectomyLimb salvageHigh-risk surgical patientsNonvascular causesInitial angiogramSevere comorbiditiesSurgical patientsProcedural successThrombolytic therapyImmediate blood flowBlood flowSix monthsPatientsThrombectomyIschemiaContraindicationsImmediate resultsHospitalLimbSalvageSurvivorsVesselsComorbidities