2015
Impact of Bleeding and Bivalirudin Therapy on Mortality Risk in Women Undergoing Percutaneous Coronary Intervention (from the REPLACE-2, ACUITY, and HORIZONS-AMI Trials)
Ng VG, Baumbach A, Grinfeld L, Lincoff AM, Mehran R, Stone GW, Lansky AJ. Impact of Bleeding and Bivalirudin Therapy on Mortality Risk in Women Undergoing Percutaneous Coronary Intervention (from the REPLACE-2, ACUITY, and HORIZONS-AMI Trials). The American Journal Of Cardiology 2015, 117: 186-191. PMID: 26704028, DOI: 10.1016/j.amjcard.2015.10.029.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionStrong independent predictorMajor bleedingMortality rateBivalirudin therapyCoronary interventionIndependent predictorsFemale genderGlycoprotein IIb/IIIa inhibitor treatmentST-segment elevation myocardial infarctionNon-coronary artery bypassPatient-level pooled analysisImpact of bleedingMajor bleeding ratesPronounced clinical benefitOutcomes of patientsAcute coronary syndromeCohort of patientsElevation myocardial infarctionArtery bypassCoronary syndromeMultivariate adjustmentStandard therapyClinical benefitPooled analysis
2005
Impact and Determinants of Left Ventricular Function in Patients Undergoing Primary Percutaneous Coronary Intervention in Acute Myocardial Infarction
Halkin A, Stone GW, Dixon SR, Grines CL, Tcheng JE, Cox DA, Garcia E, Brodie B, Stuckey TD, Mehran R, Lansky AJ. Impact and Determinants of Left Ventricular Function in Patients Undergoing Primary Percutaneous Coronary Intervention in Acute Myocardial Infarction. The American Journal Of Cardiology 2005, 96: 325-331. PMID: 16054451, DOI: 10.1016/j.amjcard.2005.03.069.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionLeft ventricular functionBaseline left ventricular functionPrimary angioplastyBaseline LVEFVentricular functionIndependent predictorsIndex procedureMyocardial infarctionInfarct zone regional wall motionBaseline left ventricular dysfunctionMyocardial Infarction grade 0Primary percutaneous coronary interventionOne-year survival ratePrevious acute myocardial infarctionMultivessel coronary diseaseLeft ventricular dysfunctionPercutaneous coronary interventionVentricular ejection fractionStrong independent predictorRegional wall motionCADILLAC trialPreprocedural ThrombolysisVentricular dysfunctionCoronary intervention
2004
Prognostic utility of comparative methods for assessment of ST-segment resolution after primary angioplasty for acute myocardial infarction The controlled abciximab and device investigation to lower late angioplasty complications (CADILLAC) trial
McLaughlin M, Stone G, Aymong E, Gardner G, Mehran R, Lansky A, Grines C, Tcheng J, Cox D, Stuckey T, Garcia E, Guagliumi G, Turco M, Josephson M, Zimetbaum P. Prognostic utility of comparative methods for assessment of ST-segment resolution after primary angioplasty for acute myocardial infarction The controlled abciximab and device investigation to lower late angioplasty complications (CADILLAC) trial. Journal Of The American College Of Cardiology 2004, 44: 1215-1223. PMID: 15364322, DOI: 10.1016/j.jacc.2004.06.053.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryCoronary AngiographyCoronary CirculationElectrocardiographyFemaleHeart Conduction SystemHumansMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionPostoperative ComplicationsPredictive Value of TestsPrognosisProspective StudiesRecurrenceRisk FactorsStatistics as TopicSurvival AnalysisTreatment OutcomeConceptsST-segment elevation resolutionPrimary percutaneous coronary interventionPrimary PCIST-segment elevationAcute myocardial infarctionLate Angioplasty Complications (CADILLAC) trialMaximum ST-segment elevationCombined end pointComplications TrialMyocardial infarctionBaseline ST-segment elevationEnd pointInfarct-related artery patencyHigh-risk categorizationPost-PCI electrocardiogramsST-segment resolutionPercutaneous coronary interventionTarget vessel patencyStrong independent predictorControlled AbciximabPrimary angioplastyArtery patencyCoronary interventionIndependent predictorsPrognostic utility
1999
Creatine Kinase-MB Enzyme Elevation Following Successful Saphenous Vein Graft Intervention Is Associated With Late Mortality
Hong M, Mehran R, Dangas G, Mintz G, Lansky A, Pichard A, Kent K, Satler L, Stone G, Leon M. Creatine Kinase-MB Enzyme Elevation Following Successful Saphenous Vein Graft Intervention Is Associated With Late Mortality. Circulation 1999, 100: 2400-2405. PMID: 10595951, DOI: 10.1161/01.cir.100.24.2400.Peer-Reviewed Original ResearchConceptsCK-MB elevationSaphenous vein graft interventionCK-MB riseVein graft interventionLate mortalityGraft interventionClinical eventsCreatine kinase‐MB enzyme elevationPeriprocedural CK-MB elevationNormal CK-MBMajor clinical eventsLate clinical eventsCreatine kinase elevationStrong independent predictorHospital complicationsSVG angioplastySVG interventionSVG lesionsConsecutive patientsDiabetes mellitusEnzyme elevationIndependent predictorsPrognostic significanceCK-MBMultivariate analysis