2024
Long-term outcomes of ischaemia with no obstructive coronary artery disease (INOCA): a systematic review and meta-analysis
Odanović N, Schwann A, Zhang Z, Kapadia S, Kunnirickal S, Parise H, Tirziu D, Ilic I, Lansky A, Pietras C, Shah S. Long-term outcomes of ischaemia with no obstructive coronary artery disease (INOCA): a systematic review and meta-analysis. Open Heart 2024, 11: e002852. PMID: 39353703, PMCID: PMC11448144, DOI: 10.1136/openhrt-2024-002852.Peer-Reviewed Original ResearchConceptsCoronary Vasomotor Disorders International Study GroupRate of MACEReduced coronary flow reserveCoronary flow reservePrognosis of patientsVasospastic anginaPatient yearsMyocardial infarctionPrimary outcomeIncidence of primary outcomeLong-term prognosis of patientsSystematic reviewMeta-analysisLong-term prognosisInternational Study GroupAdverse cardiovascular eventsLong-term outcomesImaging stress testsMeta-analysis of studiesRandom-effects modelWeb of ScienceINOCACardiovascular eventsFollow-upVasomotor disordersPercutaneous Coronary Revascularization Strategies After Myocardial Infarction A Systematic Review and Network Meta-Analysis
Reddy R, Howard J, Jamil Y, Madhavan M, Nanna M, Lansky A, Leon M, Ahmad Y. Percutaneous Coronary Revascularization Strategies After Myocardial Infarction A Systematic Review and Network Meta-Analysis. Journal Of The American College Of Cardiology 2024, 84: 276-294. PMID: 38986670, DOI: 10.1016/j.jacc.2024.04.051.Peer-Reviewed Original ResearchConceptsRelative riskCardiovascular mortalityMyocardial infarctionMultivessel coronary artery diseaseAll-cause mortalityAdverse cardiac eventsST-segment elevation myocardial infarctionComplete revascularizationCoronary artery diseaseBayesian network meta-analysesMortality reductionA systematic reviewNetwork meta-analysesElevation myocardial infarctionSystematic reviewMeta-analysesCardiac eventsArtery diseasePrimary outcomeNetwork meta-analysisRevascularization strategyMeta-analysisHead-to-head trialsCoronary revascularization strategyAcute kidney injuryAngiographic Characteristics and Clinical Outcomes in Patients With Chronic Kidney Disease Undergoing Impella-Supported High-Risk Percutaneous Coronary Intervention: Insights From the cVAD PROTECT III Study
Bharadwaj A, Abu-Much A, Maini A, Zhou Z, Li Y, Batchelor W, Grines C, Baron S, Redfors B, Lansky A, Basir M, O’Neill W. Angiographic Characteristics and Clinical Outcomes in Patients With Chronic Kidney Disease Undergoing Impella-Supported High-Risk Percutaneous Coronary Intervention: Insights From the cVAD PROTECT III Study. Circulation Cardiovascular Interventions 2024, 17: e013503. PMID: 38708609, PMCID: PMC11239095, DOI: 10.1161/circinterventions.123.013503.Peer-Reviewed Original ResearchChronic kidney diseaseHigh-risk percutaneous coronary interventionPercutaneous coronary interventionAdvanced chronic kidney diseaseIII studiesCerebrovascular eventsAngiographic characteristicsClinical outcomesCoronary calcificationCoronary interventionSevere coronary calcificationCardiac Surgery scoreHigh-risk patientsLong-term outcomesPercutaneous coronary intervention complicationsPCI-related complicationsPrevalence of hypertensionPeripheral arterial diseaseCoronary complicationsBaseline comorbiditiesSurgery scoreArtery diseasePrimary outcomeEGFRKidney diseaseIntravascular Imaging–Guided Versus Angiography‐Guided Percutaneous Coronary Intervention: A Systematic Review and Meta‐Analysis of Randomized Trials
Sreenivasan J, Reddy R, Jamil Y, Malik A, Chamie D, Howard J, Nanna M, Mintz G, Maehara A, Ali Z, Moses J, Chen S, Chieffo A, Colombo A, Leon M, Lansky A, Ahmad Y. Intravascular Imaging–Guided Versus Angiography‐Guided Percutaneous Coronary Intervention: A Systematic Review and Meta‐Analysis of Randomized Trials. Journal Of The American Heart Association 2024, 13: e031111. PMID: 38214263, PMCID: PMC10926835, DOI: 10.1161/jaha.123.031111.Peer-Reviewed Original ResearchConceptsAdverse cardiac eventsPercutaneous coronary interventionAngiography-guided percutaneous coronary interventionTarget vessel revascularizationTarget-lesion revascularizationCardiac eventsCardiac deathImaging-guided percutaneous coronary interventionWeighted mean follow-up durationMeta-analysisPrimary outcomeMean follow-up durationStent thrombosisMeta-analysis of randomized trialsStudy-level meta-analysisComplex lesion subsetsIntravascular imagingAll-cause deathRandom-effects meta-analysisStandard of careIntention-to-treat principleUpdates of clinical guidelinesMixed-effects meta-regressionComplex percutaneous coronary interventionIntravascular imaging-guided percutaneous coronary intervention
2023
Stroke reduction by cerebral embolic protection devices in transcatheter aortic valve implantation: a systematic review and Bayesian meta-analysis
Heuts S, Gabrio A, Veenstra L, Maesen B, Kats S, Maessen J, Walton A, Nanayakkara S, Lansky A, van 't Hof A, Vriesendorp P. Stroke reduction by cerebral embolic protection devices in transcatheter aortic valve implantation: a systematic review and Bayesian meta-analysis. Heart 2023, 110: 757-765. PMID: 37996242, DOI: 10.1136/heartjnl-2023-323359.Peer-Reviewed Original ResearchTranscatheter aortic valve implantationCerebral embolic protectionAbsolute risk differenceAortic valve implantationRelative riskTAVI patientsValve implantationSystematic reviewCerebral embolic protection devicesMedian relative riskEmbolic protection devicesMultiple sensitivity analysesEmbolic protectionPrimary outcomeFuture trialsStandard treatmentStroke reductionBaseline riskRisk differenceElectronic databasesExpert consensusNew-generation devicesSecondary analysisStrokeRelevant reductionProspective, randomized, multicenter clinical study comparing a self-expanding covered stent to percutaneous transluminal angioplasty for treatment of upper extremity hemodialysis arteriovenous fistula stenosis
Dolmatch B, Cabrera T, Pergola P, Balamuthusamy S, Makris A, Cooper R, Moore E, Licht J, Macaulay E, Maleux G, Pfammatter T, Settlage R, Cristea E, Lansky A, Investigators A, Dolmatch B, Goh G, Hawkins S, Macaulay E, Spark I, de Graff R, Deutschmann H, Kickuth R, Maleux G, Pfammatter T, Kirksey L, Mendes R, Aruny J, Ali V, Cabrera T, Pergola P, Sharma D, Moore E, Shah H, Dwyer A, Yee D, Teng W, Cooper R, Balamuthusamy S, Lipkowitz G, Saad T, Licht J, Makris A, Rogers T, Burgess J, Hoggard J. Prospective, randomized, multicenter clinical study comparing a self-expanding covered stent to percutaneous transluminal angioplasty for treatment of upper extremity hemodialysis arteriovenous fistula stenosis. Kidney International 2023, 104: 189-200. PMID: 36990214, DOI: 10.1016/j.kint.2023.03.015.Peer-Reviewed Original ResearchConceptsTarget lesion primary patencyAccess circuit primary patencyPercutaneous transluminal angioplastyTarget lesion reinterventionPrimary patencyTransluminal angioplastyArteriovenous fistulaAVF stenosisAdditional clinical outcomesCircuit primary patencyCovered stent groupLesion primary patencyMulticenter clinical studyHemodialysis arteriovenous fistula stenosisArteriovenous fistula stenosisHemodialysis patientsPrimary outcomeRandomized studyClinical outcomesAVF dysfunctionStent groupClinical studiesFistula stenosisSix monthsPatients
2021
The influence of biological age and sex on long-term outcome after percutaneous coronary intervention for ST-elevation myocardial infarction.
Rathod KS, Jones DA, Jain AK, Lim P, MacCarthy PA, Rakhit R, Lockie T, Kalra S, Dalby MC, Malik IS, Whitbread M, Firoozi S, Bogle R, Redwood S, Cooper J, Gupta A, Lansky A, Wragg A, Mathur A, Ahluwalia A. The influence of biological age and sex on long-term outcome after percutaneous coronary intervention for ST-elevation myocardial infarction. Am J Cardiovasc Dis 2021, 11: 659-678. PMID: 34849299, PMCID: PMC8611266.Peer-Reviewed Original ResearchST-segment elevation myocardial infarctionCause mortalityFemale sexCox analysisMyocardial infarctionST-elevation myocardial infarctionAge-matched menObservational cohort studyElevation myocardial infarctionPercutaneous coronary interventionKaplan-Meier analysisLong-term outcomesProportional hazards modelSub-group analysisHigh mortality rateYears of agePost-PCIPrimary PCICoronary interventionSTEMI patientsCohort studyMultivariate adjustmentPrimary outcomeUnivariate predictorsMenopausal years
2020
Frequency of Management of Cardiogenic Shock With Mechanical Circulatory Support Devices According to Race
Kim Y, Park J, Essa M, Lansky AJ, Sugeng L. Frequency of Management of Cardiogenic Shock With Mechanical Circulatory Support Devices According to Race. The American Journal Of Cardiology 2020, 125: 1782-1787. PMID: 32471549, DOI: 10.1016/j.amjcard.2020.03.025.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionMechanical circulatory supportCardiogenic shockNational Inpatient SampleHospital mortalityBlack patientsInpatient SampleMCS devicesPopulation-based retrospective cohort studyMCS utilizationMechanical circulatory support devicesOnly black patientsRetrospective cohort studyClinical Modification codesMultivariate logistic regressionCirculatory support devicesAcute clinical scenariosHospital outcomesCohort studyPrimary outcomeClinical outcomesHospital eventsCirculatory supportNinth RevisionMyocardial infarctionSurvival After Coronary Revascularization With Paclitaxel-Coated Balloons
Scheller B, Vukadinovic D, Jeger R, Rissanen TT, Scholz SS, Byrne R, Kleber FX, Latib A, Clever YP, Ewen S, Böhm M, Yang Y, Lansky A, Mahfoud F. Survival After Coronary Revascularization With Paclitaxel-Coated Balloons. Journal Of The American College Of Cardiology 2020, 75: 1017-1028. PMID: 32138961, DOI: 10.1016/j.jacc.2019.11.065.Peer-Reviewed Original ResearchConceptsDrug-coated balloonsPaclitaxel-coated balloonRisk of deathCause mortalityRisk ratioStent restenosisPaclitaxel drug-coated balloonPaclitaxel-coated devicesDe novo lesionsCoronary artery diseaseSuperficial femoral arteryCochrane Library databasesConfidence intervalsNumber of patientsWeb of ScienceCardiac mortalityCoronary revascularizationNovo lesionsCoronary interventionDCB groupDifferent time pointsArtery diseasePrimary outcomeFemoral arteryPeripheral arteries
2018
Primary outcomes and mechanism of action of intravascular lithotripsy in calcified, femoropopliteal lesions: Results of Disrupt PAD II
Brodmann M, Werner M, Holden A, Tepe G, Scheinert D, Schwindt A, Wolf F, Jaff M, Lansky A, Zeller T. Primary outcomes and mechanism of action of intravascular lithotripsy in calcified, femoropopliteal lesions: Results of Disrupt PAD II. Catheterization And Cardiovascular Interventions 2018, 93: 335-342. PMID: 30474206, DOI: 10.1002/ccd.27943.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overEuropeFemaleFemoral ArteryHumansLithotripsyMaleMiddle AgedNew ZealandPeripheral Arterial DiseasePopliteal ArteryProgression-Free SurvivalProspective StudiesRetreatmentRisk FactorsSeverity of Illness IndexTime FactorsUltrasonic TherapyVascular CalcificationVascular PatencyConceptsMajor adverse eventsIntravascular lithotripsyPrimary patencyDuplex ultrasonographyPAD IIAcute procedure successFinal residual stenosisPrimary effectiveness endpointPrimary safety endpointKey secondary endpointPeripheral arterial stenosisMulti-center studySonic pressure wavesMechanism of actionCompelling safetyEffectiveness endpointAnti-proliferative therapiesSafety endpointSecondary endpointsVascular complicationsAdverse eventsFemoropopliteal lesionsResidual stenosisPrimary outcomeAcute gain
2012
Impact of the Presence and Extent of Incomplete Angiographic Revascularization After Percutaneous Coronary Intervention in Acute Coronary Syndromes
Rosner GF, Kirtane AJ, Genereux P, Lansky AJ, Cristea E, Gersh BJ, Weisz G, Parise H, Fahy M, Mehran R, Stone GW. Impact of the Presence and Extent of Incomplete Angiographic Revascularization After Percutaneous Coronary Intervention in Acute Coronary Syndromes. Circulation 2012, 125: 2613-2620. PMID: 22550156, DOI: 10.1161/circulationaha.111.069237.Peer-Reviewed Original ResearchConceptsMajor adverse cardiac eventsIncomplete coronary revascularizationPercutaneous coronary interventionAdverse cardiac eventsAcute coronary syndromeCoronary interventionCoronary syndromeCardiac eventsUnplanned revascularizationMyocardial infarctionMajor adverse cardiac event ratesUrgent Intervention Triage Strategy (ACUITY) trialAdverse cardiac event ratesCardiac event rateReference vessel diameterEntire coronary treeAcute CatheterizationAngiographic revascularizationCoronary revascularizationIndependent predictorsPrimary outcomeMultivariable analysisStrategy trialQuantitative angiographyClinical significance