2007
Assessing intermediate left main coronary lesions using intravascular ultrasound
Sano K, Mintz GS, Carlier SG, de Ribamar Costa J, Qian J, Missel E, Shan S, Franklin-Bond T, Boland P, Weisz G, Moussa I, Dangas GD, Mehran R, Lansky AJ, Kreps EM, Collins MB, Stone GW, Leon MB, Moses JW. Assessing intermediate left main coronary lesions using intravascular ultrasound. American Heart Journal 2007, 154: 983-988. PMID: 17967608, DOI: 10.1016/j.ahj.2007.07.001.Peer-Reviewed Original ResearchConceptsLeft main coronary artery stenosisQuantitative coronary angiographySignificant left main coronary artery stenosisMinimal lumen areaIntravascular ultrasoundOstial lesionsIVUS analysisMain coronary artery stenosisLumen areaIVUS minimal lumen areaLeft main ostiumAmbiguous left main coronary artery stenosisCoronary artery stenosisMain coronary lesionsMinimal lumen diameterIVUS evaluationConsecutive patientsCoronary angiographyCoronary lesionsSuch patientsArtery stenosisPlaque burdenDiameter stenosisMain ostiumPhysiologic assessment
2003
Vascular brachytherapy using a beta emitter source in diabetic patients with in-stent restenosis: Angiographic and clinical outcomes
Suntharalingam M, Laskey WK, Tantibhedhyangkul W, Lansky A, Teirstein P, Bass T, Silber S, Rutherford B, Wilmer C, Popma JJ, Kuntz R, Bonan R. Vascular brachytherapy using a beta emitter source in diabetic patients with in-stent restenosis: Angiographic and clinical outcomes. International Journal Of Radiation Oncology • Biology • Physics 2003, 57: 536-542. PMID: 12957267, DOI: 10.1016/s0360-3016(03)00537-6.Peer-Reviewed Original ResearchConceptsVessel revascularization ratePercutaneous coronary interventionDiabetic patientsNondiabetic patientsVascular brachytherapyNondiabetic counterpartsStent restenosisRevascularization ratesCoronary interventionLess target lesion revascularizationConventional percutaneous coronary interventionBinary angiographic restenosisAngiographic restenosis rateTarget lesion revascularizationReference vessel diameterComplex coronary lesionsMinimal lumen diameterStudy of patientsPercent diameter stenosisVessel diameterTreatment effectsBeta-Cath SystemBreslow-Day testLesion revascularizationAngiographic restenosis
2001
Stent Thrombosis in the Modern Era
Cutlip D, Baim D, Ho K, Popma J, Lansky A, Cohen D, Carrozza J, Chauhan M, Rodriguez O, Kuntz R. Stent Thrombosis in the Modern Era. Circulation 2001, 103: 1967-1971. PMID: 11306525, DOI: 10.1161/01.cir.103.15.1967.Peer-Reviewed Original ResearchMeSH KeywordsAspirinBlood Vessel Prosthesis ImplantationCausalityCoronary DiseaseCoronary ThrombosisEndpoint DeterminationFemaleGraft Occlusion, VascularHumansIncidenceLogistic ModelsMaleMiddle AgedMulticenter Studies as TopicMyocardial RevascularizationOdds RatioPlatelet Aggregation InhibitorsRandomized Controlled Trials as TopicSurvival RateTiclopidineTreatment OutcomeConceptsTotal stent lengthStent thrombosisAntiplatelet therapyStent lengthClinical consequencesFinal minimal lumen diameterLumen diameterNative coronary artery lesionsAngiographic stent thrombosisClinical stent thrombosisHigh-pressure deploymentRoutine antiplatelet therapyCoronary artery lesionsIncidence of deathMinimal lumen diameterProcedure-related variablesSecond-generation stentsCoronary stent trialsSerious clinical consequencesFinal lumen diameterNonrandomized registryAntithrombotic regimensArtery lesionsPersistent dissectionMyocardial infarctionTreatment of focal in-stent restenosis with balloon angioplasty alone versus stenting: Short- and long-term results
Mehran R, Dangas G, Abizaid A, Lansky A, Mintz G, Pichard A, Satler L, Kent K, Waksman R, Stone G, Leon M. Treatment of focal in-stent restenosis with balloon angioplasty alone versus stenting: Short- and long-term results. American Heart Journal 2001, 141: 610-614. PMID: 11275928, DOI: 10.1067/mhj.2001.113998.Peer-Reviewed Original ResearchConceptsPercutaneous transluminal coronary angioplastyMinimal lumen diameterLong-term clinical resultsFocal ISRStent groupClinical resultsStent restenosisLarger reference vessel diameterLesion lengthLesion revascularization rateTarget lesion revascularizationReference vessel diameterResidual diameter stenosisTransluminal coronary angioplastyLong-term resultsQ-wave infarctionPTCA groupUrgent revascularizationAngiographic successLesion revascularizationRevascularization ratesAdditional stentingBaseline characteristicsCoronary angioplastyDiabetic patients
2000
The PARAGON stent study: a randomized trial of a new martensitic nitinol stent versus the Palmaz-Schatz stent for treatment of complex native coronary arterial lesions
Holmes D, Lansky A, Kuntz R, Bell M, Buchbinder M, Fortuna R, O’Shaughnessy C, Popma J, Investigators F. The PARAGON stent study: a randomized trial of a new martensitic nitinol stent versus the Palmaz-Schatz stent for treatment of complex native coronary arterial lesions. The American Journal Of Cardiology 2000, 86: 1073-1079. PMID: 11074202, DOI: 10.1016/s0002-9149(00)01162-0.Peer-Reviewed Original ResearchConceptsStent minimal lumen diameterTarget vessel failureMinimal lumen diameterAngiographic restenosisPalmaz-SchatzLumen diameterPS stentEnd pointSignificant differencesAverage stent lengthBinary angiographic restenosisInfrequent adverse eventsPrimary end pointSecondary end pointsSmaller reference vesselsCoronary arterial lesionsNative coronary lesionsPrior bypass surgeryLong-term outcomesPalmaz-Schatz stentsPrior restenosisLesion revascularizationPercutaneous revascularizationBypass surgeryClinical restenosisRandomized Comparison of GR-II Stent and Palmaz-Schatz Stent for Elective Treatment of Coronary Stenoses
Lansky A, Roubin G, O’Shaughnessy C, Moore P, Dean L, Raizner A, Safian R, Zidar J, Kerr J, Popma J, Mehran R, Kuntz R, Leon M. Randomized Comparison of GR-II Stent and Palmaz-Schatz Stent for Elective Treatment of Coronary Stenoses. Circulation 2000, 102: 1364-1368. PMID: 10993853, DOI: 10.1161/01.cir.102.12.1364.Peer-Reviewed Original ResearchConceptsCoronary stenosisPalmaz-SchatzElective treatmentDe novo native coronary stenosisStent minimal lumen diameterMultivariate logistic regression analysisPrimary end pointTarget lesion revascularizationFree survival rateStent thrombosis ratesLong-term followNative coronary stenosisMinimal lumen diameterLogistic regression analysisPalmaz-Schatz stentsBalloon angioplasty proceduresRestenosis frequencyAngiographic restenosisLesion revascularizationProspective multicenterTLR rateFree survivalAcute treatmentConsecutive patientsDiabetes mellitusImportance of lesion length on new device angioplasty of native coronary arteries
Saucedo J, Kennard E, Popma J, Talley D, Lansky A, Leon M, Baim D. Importance of lesion length on new device angioplasty of native coronary arteries. Catheterization And Cardiovascular Interventions 2000, 50: 19-25. PMID: 10816274, DOI: 10.1002/(sici)1522-726x(200005)50:1<19::aid-ccd4>3.0.co;2-h.Peer-Reviewed Original ResearchConceptsTarget lesion revascularizationNew device angioplastyMore target lesion revascularizationLesion revascularizationLong lesionsLesion lengthRight coronary artery diseaseSmaller minimal lumen diameterLong lesion groupMore multivessel diseaseNative coronary arteriesCoronary artery diseaseCoronary Intervention RegistryEarly clinical eventsMinimal lumen diameterLonger lesion lengthMultivessel diseaseAngiographic outcomesIntervention RegistryArtery diseaseClinical outcomesHospital eventsTotal occlusionClinical eventsCoronary arteryAtherosclerotic Plaque Burden and CK-MB Enzyme Elevation After Coronary Interventions
Mehran R, Dangas G, Mintz G, Lansky A, Pichard A, Satler L, Kent K, Stone G, Leon M. Atherosclerotic Plaque Burden and CK-MB Enzyme Elevation After Coronary Interventions. Circulation 2000, 101: 604-610. PMID: 10673251, DOI: 10.1161/01.cir.101.6.604.Peer-Reviewed Original ResearchConceptsCK-MB elevationAtherosclerotic plaque burdenPreintervention intravascular ultrasoundPlaque burdenTimes upper limitIntravascular ultrasoundCoronary interventionSerum creatine kinase MB fractionPlatelet glycoprotein IIb/IIIa inhibitorsGlycoprotein IIb/IIIa inhibitorsReference segmentsFinal minimal lumen diameterLesion site plaque burdenIIb/IIIa inhibitorsCreatine kinase MB fractionAngiographic lesion morphologyDe novo lesionsNative coronary lesionsPercutaneous coronary interventionMinimal lumen diameterDiffuse atherosclerotic diseaseCatheter-based interventionsCross-sectional narrowingAtheroablative techniquesLate mortalityOptimally deployed stents in the treatment of restenotic versus de novo lesions
Gruberg L, Hong M, Mintz G, Mehran R, Waksman R, Dangas G, Kent K, Pichard A, Satler L, Lansky A, Kornowski R, Stone G, Leon M. Optimally deployed stents in the treatment of restenotic versus de novo lesions. The American Journal Of Cardiology 2000, 85: 333-337. PMID: 11078302, DOI: 10.1016/s0002-9149(99)00742-0.Peer-Reviewed Original ResearchConceptsDe novo lesionsOptimal stent deploymentTarget lesion revascularizationEvent-free survivalVein graft lesionsNovo lesionsLong-term outcomesMinimal lumen diameterRestenotic lesionsStent deploymentLesion revascularizationGraft lesionsDiabetes mellitusMyocardial infarctionHigh incidenceNon-Q-wave myocardial infarctionDe novo lesions groupFinal minimal lumen diameterLumen diameterSaphenous vein graft lesionsIndependent risk factorDe novo groupIncidence of deathStent deployment techniquesStatistical significant differenceRelation of coronary artery size to one-year clinical events after new device angioplasty of native coronary arteries (a New Approach to Coronary Intervention [NACI] Registry report)
Saucedo J, Popma J, Kennard E, Talley J, Lansky A, Leon M, Baim D, Investigators F. Relation of coronary artery size to one-year clinical events after new device angioplasty of native coronary arteries (a New Approach to Coronary Intervention [NACI] Registry report). The American Journal Of Cardiology 2000, 85: 166-171. PMID: 10955371, DOI: 10.1016/s0002-9149(99)00649-9.Peer-Reviewed Original ResearchConceptsReference vessel diameterNew device angioplastyNative coronary arteriesMinimal lumen diameterClinical eventsAngiographic outcomesCoronary arteryFinal minimal lumen diameterFinal percent diameter stenosisMajor adverse clinical eventsOne-year clinical eventsSmaller reference vessel diameterBaseline lesion characteristicsRisk of TLRCombined end pointAdverse clinical eventsCoronary artery diseaseCoronary Intervention RegistryEarly clinical eventsIncidence of deathSmall vesselsCoronary artery sizePercent diameter stenosisLesion revascularizationMultivessel disease
1999
Procedural and late outcomes following MULTI-LINK DUET coronary stent deployment
Kereiakes D, Midei M, Hermiller J, O’Shaughnessy C, Schlofmitz R, Yakubov S, Fink S, Hu F, Nishimura N, Sievers M, Valentine M, Broderick T, Lansky A, Moses J. Procedural and late outcomes following MULTI-LINK DUET coronary stent deployment. The American Journal Of Cardiology 1999, 84: 1385-1390. PMID: 10606109, DOI: 10.1016/s0002-9149(99)00581-0.Peer-Reviewed Original ResearchConceptsPrimary end pointMinimal lumen diameterMulti-Link stentComposite primary end pointPostprocedural minimal lumen diameterLumen diameterEnd pointMajor cardiac eventsProspective multicenter registryQuantitative coronary angiographyCoronary stent deploymentMultivariate regression modelingAngiographic restenosisMulticenter registryAngiographic outcomesCardiac eventsCurrent smokingCoronary angiographyDiabetes mellitusIndependent predictorsLesion eccentricityProcedural successTarget stenosisStent lengthLate outcomesComparative analysis of early and late angiographic outcomes using two quantitative algorithms in the Balloon versus Optimal Atherectomy Trial (BOAT)
Lansky A, Popma J, Cutlip D, Ho K, Abizaid A, Saucedo J, Zhang Y, Senerchia C, Kuntz R, Leon M, Baim D, Investigators F. Comparative analysis of early and late angiographic outcomes using two quantitative algorithms in the Balloon versus Optimal Atherectomy Trial (BOAT). The American Journal Of Cardiology 1999, 83: 1611-1616. PMID: 10392863, DOI: 10.1016/s0002-9149(99)00166-6.Peer-Reviewed Original ResearchConceptsMinimal lumen diameterPercent diameter stenosisBaseline minimal lumen diameterDiameter stenosisReference diameterDirectional atherectomyBaseline measurementsBaseline reference diameterQuantitative angiographic analysisLate angiographic outcomeAngiographic findingsAngiographic outcomesRestenosis rateBalloon angioplastyAngiographic analysisTreatment benefitTreatment groupsAngiographic laboratoryLumen diameterStenosisIndependent observersLesion irregularityAtherectomyPatientsTrials
1997
Reliability of the Quantitative Angiographic Measurements in the New Approaches to Coronary Intervention (NACI) Registry: A Comparison of Clinical Site and Repeated Angiographic Core Laboratory Readings
Popma J, Lansky A, Yeh W, Kennard E, Keller M, Merritt A, DeFalco R, Desai A, Pacera J, Schnabel J, Niedermeyer V, Baim D, Detre K. Reliability of the Quantitative Angiographic Measurements in the New Approaches to Coronary Intervention (NACI) Registry: A Comparison of Clinical Site and Repeated Angiographic Core Laboratory Readings. The American Journal Of Cardiology 1997, 80: 19k-25k. PMID: 9409689, DOI: 10.1016/s0002-9149(97)00761-3.Peer-Reviewed Original ResearchConceptsPercentage diameter stenosisAngiographic core laboratoryCoronary Intervention RegistryQuantitative angiographic measurementsDiameter stenosisProximal vessel tortuosityCore laboratoryClinical sitesIntervention RegistryLaboratory readingsVessel tortuosityAngiographic measurementsPostprocedural minimal lumen diameterReference vessel diameterMinimal lumen diameterLesion calciumLesion ulcerationAngiographic resultsLesion eccentricityLesion morphologyNACI registryLumen diameterStenosisDigital caliper methodRegistryEarly and late assessment of the Micro Stent PL coronary stent for restenosis and suboptimal balloon angioplasty
Webb J, Popma J, Lansky A, Carere R, Rabinowitz A, Singer J, Dodek A. Early and late assessment of the Micro Stent PL coronary stent for restenosis and suboptimal balloon angioplasty. American Heart Journal 1997, 133: 369-374. PMID: 9060809, DOI: 10.1016/s0002-8703(97)70235-7.Peer-Reviewed Original ResearchConceptsBalloon angioplastyStent dislodgmentCoronary stentsManagement of dissectionMinimal lumen diameterSuboptimal balloon angioplastySite of placementAdditional patientsDistal deliveryProspective studyStent thrombosisDiameter stenosisBalloon catheterLate lossProcedural failurePatientsSix monthsLumen diameterStentsRestenosisInitial assessmentLater assessmentsAngioplastyStainless steel stentsFuture stent designs
1996
Angiographic and Clinical Outcome after Cutting Balloon Angioplasty.
Popma J, Lansky A, Purkayastha D, Hall L, Bonan R. Angiographic and Clinical Outcome after Cutting Balloon Angioplasty. Journal Of Invasive Cardiology 1996, 8 Suppl A: 12a-19a. PMID: 10785760.Peer-Reviewed Original ResearchBalloon angioplastyConventional balloon angioplastyResidual stenosisClinical outcomesBalloon useDiameter stenosisArtery ratioNon-complex coronary artery diseaseComplex coronary artery diseaseCutting Balloon AngioplastyReference artery sizeCoronary artery diseaseMinimal lumen diameterCore laboratory analysisPrevention of restenosisAngiographic core laboratory analysisNew device angioplastyHospital complicationsOstial locationAngiographic successArtery diseaseConsecutive patientsArtery sizeSignificant inverse relationshipMorphologic findings