2016
IMPROVED LEFT VENTRICULAR FUNCTION IN ISCHEMIC HEART FAILURE PATIENTS AFTER PERCUTANEOUS LEFT VENTRICULAR PARTITIONING SYSTEM IMPLANTATION: AN ANALYSIS FROM THE PARACHUTE CHINA STUDY
Ng V, Sugeng L, Lansky A, Rizzo M, Huo Y, Yang Y, Gao R. IMPROVED LEFT VENTRICULAR FUNCTION IN ISCHEMIC HEART FAILURE PATIENTS AFTER PERCUTANEOUS LEFT VENTRICULAR PARTITIONING SYSTEM IMPLANTATION: AN ANALYSIS FROM THE PARACHUTE CHINA STUDY. Journal Of The American College Of Cardiology 2016, 67: 1442. DOI: 10.1016/s0735-1097(16)31443-7.Peer-Reviewed Original Research
2013
The prognostic importance of left ventricular function in patients with ST-segment elevation myocardial infarction: the HORIZONS-AMI trial
Ng VG, Lansky AJ, Meller S, Witzenbichler B, Guagliumi G, Peruga JZ, Brodie B, Shah R, Mehran R, Stone GW. The prognostic importance of left ventricular function in patients with ST-segment elevation myocardial infarction: the HORIZONS-AMI trial. European Heart Journal Acute Cardiovascular Care 2013, 3: 67-77. PMID: 24562805, PMCID: PMC3932775, DOI: 10.1177/2048872613507149.Peer-Reviewed Original ResearchMeSH KeywordsAgedAntithrombinsCoronary AngiographyDrug-Eluting StentsElectrocardiographyFemaleFollow-Up StudiesGated Blood-Pool ImagingHirudinsHumansMaleMiddle AgedMyocardial InfarctionPeptide FragmentsPercutaneous Coronary InterventionPrognosisProspective StudiesRecombinant ProteinsTreatment OutcomeVentricular Function, LeftConceptsST-segment elevation myocardial infarctionLeft ventricular ejection fractionPaclitaxel-eluting stentsHORIZONS-AMI trialElevation myocardial infarctionLV dysfunctionLV functionMyocardial infarctionIschaemia-driven target lesion revascularizationMajor adverse cardiovascular eventsNet adverse clinical eventsPrimary percutaneous coronary interventionBaseline LV dysfunctionIndex revascularization procedureAdverse cardiovascular eventsOutcomes of patientsTarget lesion revascularizationHigh-risk patientsSubstantial clinical benefitAdverse clinical eventsNormal LV functionPercutaneous coronary interventionVentricular ejection fractionLeft ventricular functionBare metal stents
2010
THE IMPACT OF LEFT VENTRICULAR FUNCTION ON MORTALITY IN PATIENTS WITH ST-SEGMENT ELEVATION ACUTE MYOCARDIAL INFARCTION: ANALYSIS OF THE HARMONIZING OUTCOMES WITH REVASCULARIZATION AND STENTS IN ACUTE MYOCARDIAL INFARCTION (HORIZONS-AMI) STUDY
Lansky A, Ng V, Witzenbichler B, Guagliumi G, Peruga J, Goto K, Parise H, Mehran R, Stone G. THE IMPACT OF LEFT VENTRICULAR FUNCTION ON MORTALITY IN PATIENTS WITH ST-SEGMENT ELEVATION ACUTE MYOCARDIAL INFARCTION: ANALYSIS OF THE HARMONIZING OUTCOMES WITH REVASCULARIZATION AND STENTS IN ACUTE MYOCARDIAL INFARCTION (HORIZONS-AMI) STUDY. Journal Of The American College Of Cardiology 2010, 55: a186.e1741. DOI: 10.1016/s0735-1097(10)61742-1.Peer-Reviewed Original ResearchIMPACT OF LEFT VENTRICULAR FUNCTION ON MORTALITY IN PATIENTS WITH ACUTE CORONARY SYNDROMES: ANALYSIS OF THE ACUTE CATHETERIZATION AND URGENT INTERVENTION TRIAGE STRATEGY (ACUITY) TRIAL
Lansky A, Ng V, Goto K, Fahy M, Mehran R, Ebrahimian R, Hamond M, Ohman E, Feit F, Manoukian S, Lincoff M, Stone G. IMPACT OF LEFT VENTRICULAR FUNCTION ON MORTALITY IN PATIENTS WITH ACUTE CORONARY SYNDROMES: ANALYSIS OF THE ACUTE CATHETERIZATION AND URGENT INTERVENTION TRIAGE STRATEGY (ACUITY) TRIAL. Journal Of The American College Of Cardiology 2010, 55: a186.e1740. DOI: 10.1016/s0735-1097(10)61741-x.Peer-Reviewed Original Research
2006
Impact of treatment delays on outcomes of primary percutaneous coronary intervention for acute myocardial infarction: Analysis from the CADILLAC trial
Brodie BR, Stone GW, Cox DA, Stuckey TD, Turco M, Tcheng JE, Berger P, Mehran R, McLaughlin M, Costantini C, Lansky AJ, Grines CL. Impact of treatment delays on outcomes of primary percutaneous coronary intervention for acute myocardial infarction: Analysis from the CADILLAC trial. American Heart Journal 2006, 151: 1231-1238. PMID: 16781224, DOI: 10.1016/j.ahj.2005.07.016.Peer-Reviewed Original ResearchConceptsPrimary percutaneous coronary interventionPercutaneous coronary interventionAcute myocardial infarctionLow-risk patientsLeft ventricular functionOnset of symptomsTreatment delayCoronary interventionEarly reperfusionMyocardial infarctionCADILLAC trialVentricular functionComplete ST-segment resolutionPercutaneous transluminal coronary angioplastyFrequent grade 2ST-segment resolutionHigh-risk patientsSuperior clinical outcomesTransluminal coronary angioplastyMicrovascular reperfusionBalloon timeCoronary angioplastyClinical outcomesMyocardial blushPatient triage
2005
Impact and Determinants of Left Ventricular Function in Patients Undergoing Primary Percutaneous Coronary Intervention in Acute Myocardial Infarction
Halkin A, Stone GW, Dixon SR, Grines CL, Tcheng JE, Cox DA, Garcia E, Brodie B, Stuckey TD, Mehran R, Lansky AJ. Impact and Determinants of Left Ventricular Function in Patients Undergoing Primary Percutaneous Coronary Intervention in Acute Myocardial Infarction. The American Journal Of Cardiology 2005, 96: 325-331. PMID: 16054451, DOI: 10.1016/j.amjcard.2005.03.069.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionLeft ventricular functionBaseline left ventricular functionPrimary angioplastyBaseline LVEFVentricular functionIndependent predictorsIndex procedureMyocardial infarctionInfarct zone regional wall motionBaseline left ventricular dysfunctionMyocardial Infarction grade 0Primary percutaneous coronary interventionOne-year survival ratePrevious acute myocardial infarctionMultivessel coronary diseaseLeft ventricular dysfunctionPercutaneous coronary interventionVentricular ejection fractionStrong independent predictorRegional wall motionCADILLAC trialPreprocedural ThrombolysisVentricular dysfunctionCoronary interventionPrediction of Mortality After Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction The CADILLAC Risk Score
Halkin A, Singh M, Nikolsky E, Grines CL, Tcheng JE, Garcia E, Cox DA, Turco M, Stuckey TD, Na Y, Lansky AJ, Gersh BJ, O’Neill W, Mehran R, Stone GW. Prediction of Mortality After Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction The CADILLAC Risk Score. Journal Of The American College Of Cardiology 2005, 45: 1397-1405. PMID: 15862409, DOI: 10.1016/j.jacc.2005.01.041.Peer-Reviewed Original ResearchConceptsPrimary percutaneous coronary interventionPrimary PCIAcute myocardial infarctionBaseline left ventricular functionOne-year mortalityPercutaneous coronary interventionLeft ventricular functionRisk scoreCoronary interventionVentricular functionMyocardial infarctionCADILLAC risk scoreExcellent prognostic accuracyPrevious risk scoresStrata of riskAccurate risk stratificationLong-term mortalitySimple risk scoreRespective odds ratiosPrediction of mortalityRisk score modelTime of interventionInitial multivariate modelInteger scoring systemAngiographic variables
2004
869-2 Impact of intravenous beta-blockade during primary percutaneous intervention on convalescent left ventricular function
Halkin A, Grines C, Cox D, Garcia E, Mehran R, Tcheng J, Griffin J, Guagliumi G, Brodie B, Turco M, Rutherford B, Aymong E, Lansky A, Stone G. 869-2 Impact of intravenous beta-blockade during primary percutaneous intervention on convalescent left ventricular function. Journal Of The American College Of Cardiology 2004, 43: a303-a304. DOI: 10.1016/s0735-1097(04)91284-3.Peer-Reviewed Original ResearchPrimary percutaneous interventionLeft ventricular functionVentricular functionPercutaneous interventionRelation between late patency of the infarct-related artery, left ventricular function, and clinical outcomes after primary percutaneous intervention for acute myocardial infarction (CADILLAC trial)
Halkin A, Aymong E, Cox DA, Mehran R, Lansky AJ, Fahy M, Weisz G, Garcia E, Tcheng JE, Grines CL, Stone GW. Relation between late patency of the infarct-related artery, left ventricular function, and clinical outcomes after primary percutaneous intervention for acute myocardial infarction (CADILLAC trial). The American Journal Of Cardiology 2004, 93: 349-353. PMID: 14759389, DOI: 10.1016/j.amjcard.2003.10.019.Peer-Reviewed Original ResearchConceptsInfarct-related arteryPercutaneous coronary interventionAcute myocardial infarctionInfarct arteryCoronary interventionVentricular functionClinical outcomesMyocardial infarctionMyocardial Infarction trial (TIMI) grade 3 flowPrimary percutaneous coronary interventionLeft ventricular ejection fractionDegree of restenosisGrade 3 flowPrimary percutaneous interventionEvent-free survivalVentricular ejection fractionLeft ventricular functionSustained patencyRoutine followEjection fractionIndependent predictorsLate patencyPercutaneous interventionSerial measuresArtery