Diagnosis of Ischemia-Causing Coronary Stenoses by Noninvasive Fractional Flow Reserve Computed From Coronary Computed Tomographic Angiograms Results From the Prospective Multicenter DISCOVER-FLOW (Diagnosis of Ischemia-Causing Stenoses Obtained Via Noninvasive Fractional Flow Reserve) Study
Koo BK, Erglis A, Doh JH, Daniels DV, Jegere S, Kim HS, Dunning A, DeFrance T, Lansky A, Leipsic J, Min JK. Diagnosis of Ischemia-Causing Coronary Stenoses by Noninvasive Fractional Flow Reserve Computed From Coronary Computed Tomographic Angiograms Results From the Prospective Multicenter DISCOVER-FLOW (Diagnosis of Ischemia-Causing Stenoses Obtained Via Noninvasive Fractional Flow Reserve) Study. Journal Of The American College Of Cardiology 2011, 58: 1989-1997. PMID: 22032711, DOI: 10.1016/j.jacc.2011.06.066.Peer-Reviewed Original ResearchConceptsFractional flow reserveCoronary artery diseaseComputation of FFRInvasive coronary angiographyNoninvasive fractional flow reserveCCTA stenosisCoronary angiographyDiagnostic performanceFlow reserveCCTA dataPredictive valueObstructive coronary artery diseaseMeasurement of FFRComputed Tomographic AngiogramsIschemia-causing stenosisPercent of patientsCoronary artery lesionsIndependent core laboratoryInvasive fractional flow reserve