Jonathan Borak, MD
About
Biography
Jonathan Borak is Clinical Professor of Medicine at Yale School of Medicine. He received his BA with Honors from Amherst College and earned his MD at New York University. He completed a residency in internal medicine at Montreal’s Royal Victoria Hospital, was a Robert Wood Johnson Foundation Clinical Scholar at McGill University, and a Postdoctoral Fellow in Internal Medicine at Yale University. He is board certified in Internal Medicine, Occupational Medicine, and Toxicology and is a Fellow of the American College of Physicians, the American College of Occupational and Environmental Medicine, the Royal College of Physicians of Canada, the American Industrial Hygiene Association and the Academy of Toxicological Sciences.
Dr. Borak is a member of the Editorial Boards of Journal of Occupational and Environmental Medicine, Journal of Occupational and Environmental Hygiene, and Occupational Medicine. He served for ten years as Chair of the Council on Scientific Affairs of the American College of Occupational and Environmental Medicine (ACOEM) and has received numerous awards from ACOEM including the Adolph G. Kammer Merit in Authorship Award, the Robert A. Kehoe Award of Merit Recognition, and the George H. Gerchman Memorial Prize. He has also received the Harriet Hardy Award of the New England College of Occupational and Environmental Medicine.
Appointments
General Internal Medicine
Clinical ProfessorPrimary
Other Departments & Organizations
- General Internal Medicine
- Internal Medicine
- Occupational & Environmental Medicine Program
Education & Training
- MD
- New York University (1972)
- BA
- Amherst College (1968)
- Fellow
- American College of Physicians
- Fellow
- American College of Occupational and Environmental Medicine
- Fellow
- Royal College of Physicians (Canada)
Research
Overview
Dr. Borak’s research interests are in the areas of environmental and industrial toxicology, biological and clinical surveillance of toxic exposures, environmental and workplace exposure assessments, and the epidemiology of roxic exposures. Recent research projects have focused on issues such as the assessment of occupational exposures to elemental mercury, historical reconstructions of silica particulate exposures, respiratory sensitization by reactive monomers, and the clinical assessment of beryllium-related diseases. For further information on Dr. Borak and his research, please see www.jborak.com.
Medical Research Interests
Research at a Glance
Yale Co-Authors
Publications Timeline
Mark Russi, MD, MPH
Martin Slade, MPH, PhD
Publications
2018
Bronchial hyper-responsiveness: a technical update
Borak J, Lefkowitz R, Linde B. Bronchial hyper-responsiveness: a technical update. Occupational Medicine 2018, 68: 519-522. PMID: 30192977, DOI: 10.1093/occmed/kqy122.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsMethacholine challenge testingEuropean Respiratory SocietyAmerican Thoracic SocietyDiagnosis of asthmaNew guidelinesAsymptomatic asthmaticsBronchoprovocation testingPD20 valuesATS guidelinesDeep inspirationRespiratory SocietyThoracic SocietyTidal breathingChallenge testingHand searchSystematic reviewClinical testsLongitudinal assessmentBreath holdingAsthmaPD20CliniciansGuidelinesDelivery systemTechnical update
2017
Persistence of mercury-induced motor and sensory neurotoxicity: systematic review of workers previously exposed to mercury vapor
Fields CA, Borak J, Louis ED. Persistence of mercury-induced motor and sensory neurotoxicity: systematic review of workers previously exposed to mercury vapor. Critical Reviews In Toxicology 2017, 47: 849-870. PMID: 28722535, PMCID: PMC5962347, DOI: 10.1080/10408444.2017.1342599.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsPhysical examinationElectrophysiological studiesSystematic reviewCessation of exposureHigh-dose exposurePrevious exposure studiesMercury workersSensory neurotoxicityNeurological findingsHistorical groupNeurobehavioral testsNeurotoxic effectsNB testingNeurotoxicityLimited available dataLongitudinal studyExposureFunctional significanceSensory effectsReviewHgCohortWorkersYearsStudyMercury-induced motor and sensory neurotoxicity: systematic review of workers currently exposed to mercury vapor
Fields CA, Borak J, Louis ED. Mercury-induced motor and sensory neurotoxicity: systematic review of workers currently exposed to mercury vapor. Critical Reviews In Toxicology 2017, 47: 815-848. PMID: 28718354, PMCID: PMC5931703, DOI: 10.1080/10408444.2017.1342598.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsPhysical examinationMercury workersUrine mercury levelsStudy of neurotoxicityDental cohortNB outcomesSensory neurotoxicityAbnormal reflexesEligible studiesImpaired coordinationNeurobehavioral testsPE findingsNeurological effectsElectrophysiological studiesSystematic reviewNeurotoxicityNB testingManual dexterityNB testsTremorExposureOutcomesHistorical exposureMercury levelsTextbook chapters
2016
Chronic Beryllium Disease
Borak J. Chronic Beryllium Disease. Journal Of Occupational And Environmental Medicine 2016, 58: e355-e361. PMID: 27820771, DOI: 10.1097/jom.0000000000000869.Peer-Reviewed Original ResearchCitationsAltmetric
2015
Bronchial hyperresponsiveness
Borak J, Lefkowitz RY. Bronchial hyperresponsiveness. Occupational Medicine 2015, 66: 95-105. PMID: 26590957, DOI: 10.1093/occmed/kqv158.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsBronchial hyperresponsivenessBronchoprovocation testingChronic obstructive pulmonary disease patientsVariety of stimuliAssessment of BHRPrevalence of BHRObstructive pulmonary disease patientsPulmonary disease patientsDiagnosis of asthmaStudy of smokersGreat clinical valueBHR testingAirway diseaseLung diseaseDisease patientsClinical valueGeneral populationPathological mechanismsAsthmaHand searchSystematic reviewClinical patientsPatientsWorking populationHyperresponsiveness
2013
Is Diacetyl a Respiratory Sensitizer? A Reconsideration Using QSAR, QMM, and Competition Experiments
Dworak J, Roberts D, Calter M, Fields C, Borak J. Is Diacetyl a Respiratory Sensitizer? A Reconsideration Using QSAR, QMM, and Competition Experiments. Chemical Research In Toxicology 2013, 26: 631-633. PMID: 23593960, DOI: 10.1021/tx400097v.Peer-Reviewed Original ResearchCitationsMeSH Keywords and Concepts
2012
Ecological Bias and Data Entry Errors
Borak J, Slade M, Allen R, Salipante-Zaidel C, Fields C. Ecological Bias and Data Entry Errors. Journal Of Occupational And Environmental Medicine 2012, 54: 770-773. DOI: 10.1097/jom.0b013e31825cb7c4.Peer-Reviewed Original ResearchCitationsAltmetricMortality Disparities in Appalachia
Borak J, Salipante-Zaidel C, Slade MD, Fields CA. Mortality Disparities in Appalachia. Journal Of Occupational And Environmental Medicine 2012, 54: 146-156. PMID: 22258162, DOI: 10.1097/jom.0b013e318246f395.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and Concepts
2011
Heavy Metals
Fields C, Borak J. Heavy Metals. Journal Of Occupational And Environmental Medicine 2011, 53: 587. DOI: 10.1097/jom.0b013e318216d0f5.Peer-Reviewed Original ResearchMethyl methacrylate and respiratory sensitization: A Critical review
Borak J, Fields C, Andrews LS, Pemberton MA. Methyl methacrylate and respiratory sensitization: A Critical review. Critical Reviews In Toxicology 2011, 41: 230-268. PMID: 21401327, PMCID: PMC3072694, DOI: 10.3109/10408444.2010.532768.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsRespiratory sensitizersRespiratory sensitizationLocal lymph nodesUpper respiratory tractIrritation of eyesShort-term peak exposuresOccupational asthmaLymph nodesHypersensitivity pneumonitisCase reportRespiratory tractRespiratory effectsGuinea pigsNonspecific cytotoxicityRespiratory irritantsMedicine reportWorker studiesAsthmaSensitization testSkin sensitizationPeak exposuresDermal sensitizerVivo studiesToxicology literatureSensitization
News & Links
News
- February 16, 2010Source: Yale Daily News
What's in your water?
- September 15, 2002
Jonathan B. Borak, M.D.
- January 15, 2002
Lessons from anthrax
- December 15, 1999
Jonathan B. Borak, M.D.