About
Titles
Research Scientist
Appointments
Anesthesiology
Research ScientistPrimary
Other Departments & Organizations
- Anesthesiology
- Magnetic Resonance Research Center
Research
Research at a Glance
Yale Co-Authors
Frequent collaborators of Hedok Lee's published research.
Helene Benveniste, MD, PhD
Sunil Koundal
Zachary Gursky, PhD
Publications
2024
Divergent brain solute clearance in rat models of cerebral amyloid angiopathy and Alzheimer’s disease
Koundal S, Chen X, Gursky Z, Lee H, Xu K, Liang F, Xie Z, Xu F, Lin H, Van Nostrand W, Gu X, Elkin R, Tannenbaum A, Benveniste H. Divergent brain solute clearance in rat models of cerebral amyloid angiopathy and Alzheimer’s disease. IScience 2024, 111463. DOI: 10.1016/j.isci.2024.111463.Peer-Reviewed Original ResearchAltmetricCerebral Proteomic Changes in the rTg-D Rat Model of Cerebral Amyloid Angiopathy Type-2 With Cortical Microhemorrhages and Cognitive Impairments
Schrader J, Majchrzak M, Xu F, Lee H, Agostinucci K, Davis J, Benveniste H, Van Nostrand W. Cerebral Proteomic Changes in the rTg-D Rat Model of Cerebral Amyloid Angiopathy Type-2 With Cortical Microhemorrhages and Cognitive Impairments. Neuroscience Insights 2024, 19: 26331055241288172. PMID: 39386146, PMCID: PMC11462563, DOI: 10.1177/26331055241288172.Peer-Reviewed Original ResearchAltmetricConceptsCerebral amyloid angiopathyPathogenesis of cerebral amyloid angiopathyTGF-b1Rat modelTGF-b1 levelsType 2Few proteinsSmooth muscle cell lossTransforming growth factor beta 1Wild-type ratsProteomic changesB proteinProteomic analysisPeptidase ATransgenic rat modelPathway analysisMolecular insightsMagnetic resonance imagingCognitive impairmentAlzheimer's diseaseCell lossAmyloid depositsRatsAmyloid angiopathyCortical microhemorrhages
2023
Author Correction: Cerebral amyloid angiopathy is associated with glymphatic transport reduction and time-delayed solute drainage along the neck arteries
Chen X, Liu X, Koundal S, Elkin R, Zhu X, Monte B, Xu F, Dai F, Pedram M, Lee H, Kipnis J, Tannenbaum A, Van Nostrand W, Benveniste H. Author Correction: Cerebral amyloid angiopathy is associated with glymphatic transport reduction and time-delayed solute drainage along the neck arteries. Nature Aging 2023, 3: 1603-1603. PMID: 38001312, DOI: 10.1038/s43587-023-00544-5.Peer-Reviewed Original ResearchAltmetric
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