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Charles Lockwood, MD

Professor (Adjunct) of Obstetrics, Gynecology, and Reproductive Sciences

About

Titles

Professor (Adjunct) of Obstetrics, Gynecology, and Reproductive Sciences

Biography

Dr. Charles J. Lockwood is Senior Vice President for USF Health, Dean of the Morsani College of Medicine and Professor of Ob/Gyn and Public Health at the University of South Florida. He also serves as an Executive Vice President at Tampa General Hospital. Previously he was Dean at The Ohio State University College of Medicine and chaired Ob/Gyn departments at Yale and NYU. He graduated magna cum laude from Brown University, received his M.D. from the University of Pennsylvania and a Master’s in Healthcare Management from the Harvard School of Public Health. Lockwood served his Ob/Gyn residency at Pennsylvania Hospital and a Maternal-Fetal Medicine fellowship at Yale. His research has been funded by two decades of federal and foundation support. He has published over 300 peer-reviewed publications (Google H-index of 83; 24,511 citations), 280 editorials, chapters and invited reviews, co-authored 5 monographs and co-edited 6 textbooks, 3 with multiple editions. He has also served on multiple journal editorial boards and is the long-standing Editor-in-Chief of Contemporary OB/GYN where his editorials have won five national publication awards. Lockwood has chaired and/or serve on numerous NIH and FDA review panels, been an examiner for the American Board of Obstetrics and Gynecology, a reviewer for LCME, and held leadership roles in multiple Ob/Gyn professional societies including serving as the President of the Society for Reproductive Investigation (SRI) and the American Gynecological and Obstetrical Society. He currently serves on the National Board of the March of Dimes Foundation. He is a member of the Sigma Xi and Alpha Omega Alpha research and medical honor societies, respectively, been named to national and/or regional “Best Doctors” lists annually since 1995, and has received multiple teaching and research awards including the SRI’s Pardi Distinguished Scientist Award, the NICHD Frontiers in Reproduction Beacon Award and the Society for Maternal-Fetal Medicine Lifetime Achievement Award. He has been elected to the American Association for the Advancement of Science (AAAS) and of the National Academy of Medicine.

Education & Training

Post Doctoral
Mount Sinai Medical School (1991)
Fellow
Yale-New Haven Hospital (1989)
Resident
Pennsylvania Hospital (1985)
MD
University of Pennsylvania Medical School (1981)
MS
Harvard School of Public Health, Healthcare Management

Research

Overview

Dr. Lockwood is the Anita O'Keefe Young Professor of Women’s Health and Chair, Department of Obstetrics Gynecology and Reproductive Sciences, Yale University School of Medicine. His clinical interests include: recurrent pregnancy loss, prematurity prevention, multi-fetal pregnancies, maternal thrombophilias and thrombosis, and prenatal diagnosis. His clinical research interests include uncovering genetic predispositions to prematurity and fetal growth restriction. His translational research is devoted to understanding the basic mechanisms underlying the maintenance of hemostasis during blastocyst invasion and the establishment of the uteroplacental circulation as well as the causes of placental abruption and abruption-related preterm delivery.

His lab has also focused on the pathophysiology of abnormal uterine bleeding (AUB) associated with the idiopathic menorrhagia, anovulation, myomas, endometrial polyps and long-term progestin-only contraceptive therapy. Of key interest to these studies is the identification of pathways which may lead to aberrant angiogenesis. Recently he has examined aberrant tissue factor expression in endometriotic endothelium as a target for therapy using the immunoconjugate molecule, ICON. He has over 220 peer reviewed publications, 39 chapters in distinguished text books, is editor of four text books, UpToDate - Obstetrics and Contemporary Ob/Gyn, the nation’s must widely read Ob/Gyn journal. He serves on the editorial board of several journals and is a former President of the the Society for Gynecologic Investigation
  • Citations: 5983
  • Citations/year: 426
  • Average citations/paper: 22.7
  • H-index: 40

Targeting tissue factor expression in endometriosis and endometrial cancer with an immunoconjugate molecule.

Uncovering the causes of abnormal uterine bleeding in patients receiving long-term progestin-only contraceptives.

Dissecting the mechanisms for progesterone receptor withdrawal in infection and abruption-associated preterm deliveries.

Uncovering the control of leukocyte traffiking in the placental bed and the role of decidual macrophages in impairning endovascular extravillous trophoblast invasion.

Research at a Glance

Yale Co-Authors

Frequent collaborators of Charles Lockwood's published research.

Publications

2024

2023

2009

Academic Achievements & Community Involvement

  • honor

    Member, Institute of Medicine

  • activity

    NICHD Reproductive Scientist Development Program,

  • activity

    American Board of Obstetrics and Gynecology

  • activity

    March of Dimes

  • activity

    Fetal endocrine system

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