Nasal Vaccine May Aid Fight Against New Viral Variants
Akiko Iwasaki and her colleagues found that intranasal vaccination provided broad-based protection against heterologous respiratory viruses in mice, while so-called systemic immunization, which uses an injection to elicit body-wide protection, did not.Source: YaleNews
Improving the Diagnosis of Heart Disease in Women
Dr. Samit Shah is leading a team to demonstrate the effectiveness of validated, but not widely administered procedures for the many women who have reduced blood flow to the heart without blocked arteries or cholesterol build-up often associated with heart disease.
Virtual Reality Game Is an Effective Tool for Vaping Prevention Among Teens
The game prompts students to practice navigating peer pressure situations involving vaping. By encouraging teens to use their own voices in simulated situations, the researchers hoped they would become better prepared to face real-world scenarios.
Sex-specific Immune Response in COVID-19 Linked to Cellular Metabolism
Researchers studying COVID-19 patients have found a metabolic pathway that is highly correlated with immune responses only in male patients, a group known to be more likely to suffer severe cases and die of the disease, representing a potential target for therapeutic intervention.Source: Yale News
WHRY Launches Studies on Endometrial Cancer, Addiction to Opioids, and Stroke
While continuing to focus on the impacts of COVID-19, the center has enlarged its research portfolio to include new projects on the prevention of endometrial cancer in a growing cohort of women at high risk, non-opioid pain management following a cesarean section for women with opioid use disorder who are in recovery, and sex differences in stroke.
Caroline Johnson Receives American Cancer Society Research Scholar Grant
Caroline Johnson, Ph.D., Assistant Professor of Epidemiology in the Department of Environmental Health Sciences at Yale School of Public Health and a member of Yale Cancer Center’s Cancer Microbiology Research Program, has received a four-year, $792,000 Research Scholar Grant from the American Cancer Society (ACS).
Deadlier Colon Cancer Develops Differently in Women and Men
WHRY-affiliated researchers have found that colon cancer tumor cells produce energy for growth differently in women and men, and that this difference is associated with a more aggressive form of tumor growth with a higher incidence in women.
Small: Yale study may help resolve bitter debate over low-cal sweeteners
Several studies in recent years have reported that low-calorie sweeteners in foods and beverages disrupt the human metabolism, promoting the development of diabetes and obesity. But other studies have found that consuming low-calorie drinks and food has little impact on metabolism and might actually aid in weight loss. A new study by Yale researchers published March 3 in the journal Cell Metabolism may help reconcile these conflicting findings.
National Academy of Medicine Elects Six Yale Faculty Members
Six Yale School of Medicine faculty members have been elected to the National Academy of Medicine (NAM). The six are among 100 new members elected by the organization to receive the honor, which recognizes individuals who have demonstrated outstanding professional achievement and commitment to service in the fields of health and medicine.Source: YaleNews
Yale Launches Comprehensive DNA Sequencing Project, With Aim of Predicting, Preventing, and Treating Gene-related Diseases
Generations, a collaboration between Yale School of Medicine and Yale New Haven Health System, is one of the largest DNA sequencing projects of its kind in the United States.
Yale-developed Scorecard Promotes Better Clinical Trial Data Sharing
A tool developed by researchers at Yale, Stanford, and Bioethics International can promote greater sharing of clinical trial data by pharmaceutical companies. While nearly one-third of the companies that the researchers assessed met standards for sharing data, others could be more transparent to the benefit of science and the public, the researchers said.
Department of Neurology Receives Major Grant to Evaluate Blood Thinners and Stroke Prevention
Yale School of Medicine has received a 5-year, $20 million grant from the National Institute of Neurological Disorders and Stroke (NINDS) to administer a Phase III trial measuring the effectiveness of using a blood thinner to prevent new strokes in patients who suffered brain hemorrhages and have atrial fibrillation, or irregular heartbeat.
Chen and Team Win Award from 2019 NIDA $100K SUD Startup Challenge
Kevin Chen, MD, fellow, National Clinical Scholars Program, and his team recently won an award as part of the 2019 NIDA $100K SUD Startup Challenge. Sponsored by the National Institute on Drug Abuse, the award is given to 10 winners for their startup projects to improve the well-being of those with substance use disorders.
Implementation Science: Putting Important Discoveries to Their Best Use
Scientific innovations are created every day, but how do we ensure that they are used efficiently and reach the people who need them most? David Chambers, DPhil, deputy director for implementation science in the Division of Cancer Control & Population Sciences at the National Cancer Institute, tackled that question during his June 25 grand rounds lecture titled “Advancing the Science of Implementation in Cancer Control: An NCI Perspective."
Yale Cancer Center Partners in Fight to Help Eliminate HPV-related Cancers
Yale Cancer Center joins the Association of American Cancer Institutes (AACI) and its partner organizations to endorse a Call to Action for our nation to work together toward the elimination of human papillomavirus (HPV)-related cancers.