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For Patients & Clinicians

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The Yale Center for Clinical Investigation (YCCI) provides the infrastructure, expertise, and oversight that enable Yale investigators to conduct hundreds of high-quality clinical trials each year. These studies span every area of medicine—from oncology and immunology to cardiovascular disease, neurology, behavioral health, and precision medicine—reflecting Yale’s mission to improve health through science and collaboration.

Clinical Trial Participants

Participating in a clinical trial offers the opportunity to play an active role in your care and contribute to the future of medicine. Participants may:

  • Gain access to promising new therapies not yet widely available
  • Receive care from leading Yale physicians and research specialists
  • Help advance scientific knowledge and improve care for others
  • Contribute to discoveries that can change how diseases are treated

All studies are reviewed and monitored to ensure participant safety and ethical conduct, and participation is always voluntary.

Find an Open Clinical Trial

Our clinical trials span every area of medicine—from oncology and immunology to cardiovascular disease, neurology, behavioral health, and precision medicine—reflecting Yale’s mission to improve health through science and collaboration.

Referring Physician Information

Yale’s clinical trials program welcomes collaboration with physicians and care teams who wish to connect their patients with emerging treatment options. Our investigators conduct studies across a broad spectrum of specialties and maintain clear, timely communication with referring clinicians throughout each patient’s participation.

Partnering with YCCI gives your patients access to:

  • Innovative, evidence-based treatments and investigational therapies
  • Multidisciplinary expertise and advanced research facilities
  • Coordinated follow-up and continuity of care within Yale’s system

Clinical Research Operations

The YCCI clinical trials operations unit is comprised of clinical research professionals that provide exceptional support and service to investigators conducting clinical research studies at Yale.