Participant-centric Trial Will Test if Antiviral Paxlovid Can Help With Long COVID
Researchers are still in the dark on the mechanisms underlying and how to treat long COVID. A new clinical trial using the oral antiviral Paxlovid will provide urgently needed insights for COVID long-haulers and their providers.
Long-covid symptoms are less common now than earlier in the pandemic
Americans infected with the coronavirus’s omicron variant are less likely to develop symptoms typical of long covid than those who had covid-19 earlier in the pandemic, according to the largest-ever study of who is most vulnerable to being sickened — or debilitated — by the virus’s lingering effects.Source: The Washington Post
Will Long COVID Research Provide Answers for Poorly Understood Diseases Like ME/CFS?
ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) is a highly disabling, severe condition that has been largely overlooked and even questioned as an illness by physicians and biomedical researchers for decades. But now, scientists including Yale's Akiko Iwasaki and Harlan Krumholz are finding parallels between post-infection long COVID and ME/CFS.
COVID-19 Virus Increases Risk for Other Infections by Disrupting Normal Mix of Gut Bacteria
Infection with the pandemic virus, SARS-CoV-2, can reduce the number of bacterial species in a patient’s gut, with the lesser diversity creating space for dangerous microbes to thrive, a new study finds.Source: NYU Langone Health
Vaccine Used in Much of the World No Match for Omicron Variant
An analysis of blood serum from 101 individuals from the Dominican Republic showed that omicron infection produced no neutralizing antibodies among those who received the standard two-shot regimen of the Sinovac vaccine. Antibody levels against omicron rose among those who had also received a booster shot of the mRNA vaccine made by Pfizer-BioNTech.Source: YaleNews
‘Triple-demic’ of respiratory illnesses launches vaccination season. Have you gotten yours?
We are amid the “triple-demic” of respiratory illnesses season that includes a significant increase in U.S. COVID-19 hospitalizations alongside annual seasonal surges in respiratory viruses like influenza and respiratory syncytial virus (RSV). YSPH Professor Sten Vermund offers timely guidance on how people can best protect themselves in this opinion piece.Source: The Baltimore Sun
COVID Likely to Peak in Colder Months as Virus Becomes Endemic in the US
As COVID-19 becomes endemic in the U.S., it will likely settle into a seasonable rhythm like influenza, becoming most active during the colder months in northern climes and subsiding in summer, according to a new study by researchers at the Yale School of Public Health and the University of North Carolina at Charlotte.
The Long History of Long COVID and Other Chronic Illnesses
The term post-acute infection syndrome refers to chronic diseases that occur after an acute viral, bacterial, or parasitic infection, including chronic Lyme and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Yale School of Medicine is investigating the many questions surrounding post-acute infection syndromes in its new Center for Infection & Immunity.
Will Uninsured Americans Be Able to Get Their COVID Shot?
The government created the Bridge Access program to help those without insurance. Does anyone care about it? Associate Professor Jason Schwartz says the public is fatigued when it comes to news about another COVID shot.Source: The Messenger
As Childhood Vaccination Rates Continue to Fall, Are We Doing Enough to Stop Anti-Vaxxers? These Doctors Say No
Pakistan made headlines around the world when officials announced they’re considering throwing parents in jail for failing to vaccinate their kids among a resurgence in polio cases. While such draconian measures are unthinkable in the United States, it’s not hard to imagine a future where the re-emergence of once-eradicated diseases becomes increasingly common.Source: The Messenger
From appointments to insurance, COVID-19 vaccine issues continue in CT
Yale School of Public Health Professor Gregg Gonsalves says that during the pandemic the American public health system and welfare system had been bolstered to the point where we had a semi-functional public health and social services apparatus. These programs have all been dismantled with the end of the public health emergency, returning us to the normal of "the unfulfilled promise of public health."Source: CT Insider
CDC will invest $262.5 million to forecast the spread of infectious diseases
The CDC, through its new Center for Forecasting and Outbreak Analytics, is doling out some $262.5 million over five years to 13 centers around the country, including to researchers in Massachusetts.Source: The Boston Globe